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Patient adherence issues in the treatment of hepatitis C.

Larrey D, Ripault MP, Pageaux GP - Patient Prefer Adherence (2014)

Bottom Line: For hepatitis C, therapeutic education may be separated into three phases: a first phase corresponding to the educative diagnosis; a second phase corresponding to support during treatment; and the third phase corresponding to support after treatment.Therapeutic education is performed using various instruments and methods specifically adapted to the needs and expectations of individual patients.Upcoming treatments for hepatitis C, with evidence for high efficacy, few side effects, and shorter duration, will certainly change the landscape of adherence and the management of therapeutic education.

View Article: PubMed Central - PubMed

Affiliation: Département d'Hépato-Gastroentérologie et Transplantation, Hôpital Saint Eloi, France ; IRB-INSERM1040, Montpellier, France.

ABSTRACT
The current standard-of-care treatments for chronic hepatitis C, based on a bitherapy that combines peginterferon alpha-2a or -2b and ribavirin for all genotypes, and on a triple therapy with the addition of an antiprotease specifically for genotype 1, are associated with a limited adherence that decreases their efficacy. The main factors limiting adherence are difficulties in taking the treatment and side effects that worsen the quality of life of the patients. Programs of therapeutic education are essential to improve adherence, quality of life, likelihood of viral suppression, improvement of liver disease, and decrease of late complications. Therapeutic education should be understood as an acquisition of decisional, technical, and social competency with the purpose of making the patient able to make health choices, realize their own life plans, and use health care resources in the best manner. The patient should be placed in the center of an organization, comprising various care workers who include social service professionals and medical staff. For hepatitis C, therapeutic education may be separated into three phases: a first phase corresponding to the educative diagnosis; a second phase corresponding to support during treatment; and the third phase corresponding to support after treatment. Therapeutic education is performed using various instruments and methods specifically adapted to the needs and expectations of individual patients. Upcoming treatments for hepatitis C, with evidence for high efficacy, few side effects, and shorter duration, will certainly change the landscape of adherence and the management of therapeutic education.

No MeSH data available.


Related in: MedlinePlus

Organization of TE.Abbreviations: HRQOL, health-related quality of life; TE, therapeutic education.
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f1-ppa-8-763: Organization of TE.Abbreviations: HRQOL, health-related quality of life; TE, therapeutic education.

Mentions: This period starts just after the discovery and announcement of HCV infection to the patient. The TE team may make the first evaluation of the patient, with parameters shown in Figure 1 and Table 1, and perform the educative diagnosis (for example, providing knowledge to the patient of the disease and treatment; evaluation of their professional and social environment; and evaluation of the hepatic and extrahepatic consequences of HCV infection, comorbidities, potential addictions, and their will with regards to the TE team).73–75


Patient adherence issues in the treatment of hepatitis C.

Larrey D, Ripault MP, Pageaux GP - Patient Prefer Adherence (2014)

Organization of TE.Abbreviations: HRQOL, health-related quality of life; TE, therapeutic education.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4043798&req=5

f1-ppa-8-763: Organization of TE.Abbreviations: HRQOL, health-related quality of life; TE, therapeutic education.
Mentions: This period starts just after the discovery and announcement of HCV infection to the patient. The TE team may make the first evaluation of the patient, with parameters shown in Figure 1 and Table 1, and perform the educative diagnosis (for example, providing knowledge to the patient of the disease and treatment; evaluation of their professional and social environment; and evaluation of the hepatic and extrahepatic consequences of HCV infection, comorbidities, potential addictions, and their will with regards to the TE team).73–75

Bottom Line: For hepatitis C, therapeutic education may be separated into three phases: a first phase corresponding to the educative diagnosis; a second phase corresponding to support during treatment; and the third phase corresponding to support after treatment.Therapeutic education is performed using various instruments and methods specifically adapted to the needs and expectations of individual patients.Upcoming treatments for hepatitis C, with evidence for high efficacy, few side effects, and shorter duration, will certainly change the landscape of adherence and the management of therapeutic education.

View Article: PubMed Central - PubMed

Affiliation: Département d'Hépato-Gastroentérologie et Transplantation, Hôpital Saint Eloi, France ; IRB-INSERM1040, Montpellier, France.

ABSTRACT
The current standard-of-care treatments for chronic hepatitis C, based on a bitherapy that combines peginterferon alpha-2a or -2b and ribavirin for all genotypes, and on a triple therapy with the addition of an antiprotease specifically for genotype 1, are associated with a limited adherence that decreases their efficacy. The main factors limiting adherence are difficulties in taking the treatment and side effects that worsen the quality of life of the patients. Programs of therapeutic education are essential to improve adherence, quality of life, likelihood of viral suppression, improvement of liver disease, and decrease of late complications. Therapeutic education should be understood as an acquisition of decisional, technical, and social competency with the purpose of making the patient able to make health choices, realize their own life plans, and use health care resources in the best manner. The patient should be placed in the center of an organization, comprising various care workers who include social service professionals and medical staff. For hepatitis C, therapeutic education may be separated into three phases: a first phase corresponding to the educative diagnosis; a second phase corresponding to support during treatment; and the third phase corresponding to support after treatment. Therapeutic education is performed using various instruments and methods specifically adapted to the needs and expectations of individual patients. Upcoming treatments for hepatitis C, with evidence for high efficacy, few side effects, and shorter duration, will certainly change the landscape of adherence and the management of therapeutic education.

No MeSH data available.


Related in: MedlinePlus