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Evaluation of through-time radial GRAPPA for functional cardiac imaging in a patient population

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Real-time cardiac imaging with through-time radial GRAPPA has been shown to yield high quality functional images [Seiberlich, et al... The goal of this work is to evaluate through-time radial GRAPPA in terms of overall scan time, quantitative measures of ESV, EDV, and EF, and image quality in a patient population. 63 patients scheduled for routine CMR examinations were scanned on a 1.5T Siemens Avanto scanner with 12-18 receiver coils in this IRB and HIPPA-compliant study... Either 26 (23 patients) or 6 (40 patients) calibration frames were collected for the through-time radial GRAPPA scan... Images were rated for specific features on a scale of 1 (no visibility) to 4 (excellent) by two board-certified cardiac imagers... The distributions of review ratings were compared using the Wilcoxon test... Examples images are shown in Figure 1... The results of the statistical analyses are shown in Table 1... The raters weakly preferred the standard images for visualizing papillary muscle when only 6 calibration frames were used, and strongly preferred the standard images for blood pool and mitral valve visualization in all cases... Scan time was significantly shorter when using through-time radial GRAPPA with either 6 or 26 calibration frames, where the averages were 5.7 min with gold-standard imaging vs. 4.7 min with radial GRAPPA using 26 calibration frames and 2.8 min with 6 calibration frames... Real-time, free-breathing functional cardiac imaging using through-time radial GRAPPA offers EF values equivalent to gold-standard cine imaging with shorter overall scan times in a general patient population... While the use of more calibration frames for through-time radial GRAPPA slightly improves the image quality, as few as 6 calibration frames per slice can be used to reduce functional imaging time to less than 3 min.

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Example images generated using standard functional imaging (first, third rows) and free-breathing, ungated through-time radial GRAPPA with 6 calibration frames (second, fourth rows) in both diastole (top) and systole (bottom) for three different slice positions.
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Figure 1: Example images generated using standard functional imaging (first, third rows) and free-breathing, ungated through-time radial GRAPPA with 6 calibration frames (second, fourth rows) in both diastole (top) and systole (bottom) for three different slice positions.

Mentions: Examples images are shown in Figure 1. The results of the statistical analyses are shown in Table 1. The measures of ESV, EDV, and EF based on the breathhold gold-standard images and the real-time radial GRAPPA images are statistically equivalent. Similarly, statistical analysis showed that the image quality scores for the endocardial border definition, myocardium, cardiac motion were equivalent for the two methods. The raters weakly preferred the standard images for visualizing papillary muscle when only 6 calibration frames were used, and strongly preferred the standard images for blood pool and mitral valve visualization in all cases. Scan time was significantly shorter when using through-time radial GRAPPA with either 6 or 26 calibration frames, where the averages were 5.7 min with gold-standard imaging vs. 4.7 min with radial GRAPPA using 26 calibration frames and 2.8 min with 6 calibration frames.


Evaluation of through-time radial GRAPPA for functional cardiac imaging in a patient population
Example images generated using standard functional imaging (first, third rows) and free-breathing, ungated through-time radial GRAPPA with 6 calibration frames (second, fourth rows) in both diastole (top) and systole (bottom) for three different slice positions.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4043333&req=5

Figure 1: Example images generated using standard functional imaging (first, third rows) and free-breathing, ungated through-time radial GRAPPA with 6 calibration frames (second, fourth rows) in both diastole (top) and systole (bottom) for three different slice positions.
Mentions: Examples images are shown in Figure 1. The results of the statistical analyses are shown in Table 1. The measures of ESV, EDV, and EF based on the breathhold gold-standard images and the real-time radial GRAPPA images are statistically equivalent. Similarly, statistical analysis showed that the image quality scores for the endocardial border definition, myocardium, cardiac motion were equivalent for the two methods. The raters weakly preferred the standard images for visualizing papillary muscle when only 6 calibration frames were used, and strongly preferred the standard images for blood pool and mitral valve visualization in all cases. Scan time was significantly shorter when using through-time radial GRAPPA with either 6 or 26 calibration frames, where the averages were 5.7 min with gold-standard imaging vs. 4.7 min with radial GRAPPA using 26 calibration frames and 2.8 min with 6 calibration frames.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Real-time cardiac imaging with through-time radial GRAPPA has been shown to yield high quality functional images [Seiberlich, et al... The goal of this work is to evaluate through-time radial GRAPPA in terms of overall scan time, quantitative measures of ESV, EDV, and EF, and image quality in a patient population. 63 patients scheduled for routine CMR examinations were scanned on a 1.5T Siemens Avanto scanner with 12-18 receiver coils in this IRB and HIPPA-compliant study... Either 26 (23 patients) or 6 (40 patients) calibration frames were collected for the through-time radial GRAPPA scan... Images were rated for specific features on a scale of 1 (no visibility) to 4 (excellent) by two board-certified cardiac imagers... The distributions of review ratings were compared using the Wilcoxon test... Examples images are shown in Figure 1... The results of the statistical analyses are shown in Table 1... The raters weakly preferred the standard images for visualizing papillary muscle when only 6 calibration frames were used, and strongly preferred the standard images for blood pool and mitral valve visualization in all cases... Scan time was significantly shorter when using through-time radial GRAPPA with either 6 or 26 calibration frames, where the averages were 5.7 min with gold-standard imaging vs. 4.7 min with radial GRAPPA using 26 calibration frames and 2.8 min with 6 calibration frames... Real-time, free-breathing functional cardiac imaging using through-time radial GRAPPA offers EF values equivalent to gold-standard cine imaging with shorter overall scan times in a general patient population... While the use of more calibration frames for through-time radial GRAPPA slightly improves the image quality, as few as 6 calibration frames per slice can be used to reduce functional imaging time to less than 3 min.

No MeSH data available.