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T1 values in discrimination between health and disease using different T1 sequences: comparison between 3'3'5-MOLLI, 3'5-MOLLI, shMOLLI and SASHA

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Several shorter sequences (3'5MOLLI, shMOLLI and SASHA) have been proposed for acquisition of T1 values... Statistical analysis was performed using SPSS... For native septal T1 imaging there was a significant difference between the health and disease using all sequences (Area under the curve, p-value: 3'3'5MOLLI vs 3'5MOLLI vs. shMOLLI vs SASHA: 0.92, p < 0.01 vs 0.89, p < 0.01, vs. 0.85, p < 0.01, 0.70, p < 0.04, Figure 1)... In discrimination between ischaemic and nonischaemic cardiomyopathy, shMOLLI and SASHA could not discriminate against ischaemic cardiomyopathy... For postcontrast T1 imaging SASHA could not discriminate between health and disease (Figure 2)... Interobserver mean differences for native septal T1 values for 3'3'5 MOLLI, 3'5 MOLLI, shMOLLI and SASHA were 1, 10, 10 and 16 (ms), respectively, whereas for post-contrast septal T1 values were 0.3, 3, 3 and 5 (ms), respectively... Intraobserver mean differences for native septal T1 values were 1, 1, 3 and 4 (ms), respectively, and post-contrast septal T1 values were 7, 10, 5 and 2 (ms), respectively... All sequences are able to discriminate between health and disease within the given sample size, where original 3'3'5 MOLLI retains superior discriminatory accuracy for native and postcontrast acquisition. 3'5MOLLI shows the nearest approximation to original 3'3'5 MOLLI values. 3'3'5 MOLLI shows superior inter and intra-observer agreement in compared to 3'5 MOLLI, shMOLLI and SASHA sequence.

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Mentions: For native septal T1 imaging there was a significant difference between the health and disease using all sequences (Area under the curve, p-value: 3'3'5MOLLI vs 3'5MOLLI vs. shMOLLI vs SASHA: 0.92, p < 0.01 vs 0.89, p < 0.01, vs. 0.85, p < 0.01, 0.70, p < 0.04, Figure 1). In discrimination between ischaemic and nonischaemic cardiomyopathy, shMOLLI and SASHA could not discriminate against ischaemic cardiomyopathy. For postcontrast T1 imaging SASHA could not discriminate between health and disease (Figure 2). Interobserver mean differences for native septal T1 values for 3'3'5 MOLLI, 3'5 MOLLI, shMOLLI and SASHA were 1, 10, 10 and 16 (ms), respectively, whereas for post-contrast septal T1 values were 0.3, 3, 3 and 5 (ms), respectively. Intraobserver mean differences for native septal T1 values were 1, 1, 3 and 4 (ms), respectively, and post-contrast septal T1 values were 7, 10, 5 and 2 (ms), respectively.


T1 values in discrimination between health and disease using different T1 sequences: comparison between 3'3'5-MOLLI, 3'5-MOLLI, shMOLLI and SASHA
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4042893&req=5

Mentions: For native septal T1 imaging there was a significant difference between the health and disease using all sequences (Area under the curve, p-value: 3'3'5MOLLI vs 3'5MOLLI vs. shMOLLI vs SASHA: 0.92, p < 0.01 vs 0.89, p < 0.01, vs. 0.85, p < 0.01, 0.70, p < 0.04, Figure 1). In discrimination between ischaemic and nonischaemic cardiomyopathy, shMOLLI and SASHA could not discriminate against ischaemic cardiomyopathy. For postcontrast T1 imaging SASHA could not discriminate between health and disease (Figure 2). Interobserver mean differences for native septal T1 values for 3'3'5 MOLLI, 3'5 MOLLI, shMOLLI and SASHA were 1, 10, 10 and 16 (ms), respectively, whereas for post-contrast septal T1 values were 0.3, 3, 3 and 5 (ms), respectively. Intraobserver mean differences for native septal T1 values were 1, 1, 3 and 4 (ms), respectively, and post-contrast septal T1 values were 7, 10, 5 and 2 (ms), respectively.

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AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Several shorter sequences (3'5MOLLI, shMOLLI and SASHA) have been proposed for acquisition of T1 values... Statistical analysis was performed using SPSS... For native septal T1 imaging there was a significant difference between the health and disease using all sequences (Area under the curve, p-value: 3'3'5MOLLI vs 3'5MOLLI vs. shMOLLI vs SASHA: 0.92, p < 0.01 vs 0.89, p < 0.01, vs. 0.85, p < 0.01, 0.70, p < 0.04, Figure 1)... In discrimination between ischaemic and nonischaemic cardiomyopathy, shMOLLI and SASHA could not discriminate against ischaemic cardiomyopathy... For postcontrast T1 imaging SASHA could not discriminate between health and disease (Figure 2)... Interobserver mean differences for native septal T1 values for 3'3'5 MOLLI, 3'5 MOLLI, shMOLLI and SASHA were 1, 10, 10 and 16 (ms), respectively, whereas for post-contrast septal T1 values were 0.3, 3, 3 and 5 (ms), respectively... Intraobserver mean differences for native septal T1 values were 1, 1, 3 and 4 (ms), respectively, and post-contrast septal T1 values were 7, 10, 5 and 2 (ms), respectively... All sequences are able to discriminate between health and disease within the given sample size, where original 3'3'5 MOLLI retains superior discriminatory accuracy for native and postcontrast acquisition. 3'5MOLLI shows the nearest approximation to original 3'3'5 MOLLI values. 3'3'5 MOLLI shows superior inter and intra-observer agreement in compared to 3'5 MOLLI, shMOLLI and SASHA sequence.

No MeSH data available.