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Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials.

Dombrowski SU, Knittle K, Avenell A, Araújo-Soares V, Sniehotta FF - BMJ (2014)

Bottom Line: Orlistat combined with behavioural interventions resulted in a -1.80 kg (-2.54 to -1.06; eight comparisons, 1738 participants) difference compared with placebo at 12 months.All orlistat studies reported higher frequencies of adverse gastrointestinal events in the experimental compared with placebo control groups.Behavioural interventions that deal with both diet and physical activity show small but significant benefits on weight loss maintenance.

View Article: PubMed Central - PubMed

Affiliation: Institute of Health and Society, Newcastle University, Baddiley-Clark Building, Newcastle upon Tyne NE2 4AX, UK School of Natural Sciences, University of Stirling, Cottrell Building, Stirling FK9 4LA, UK.

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Fig 3 Mean difference in weight change at 12 months after initial weight loss in behavioural/lifestyle studies. BC=behaviour therapy + post-treatment therapy contact condition; BCA=behaviour therapy + post-treatment therapy contact + aerobic exercise maintenance condition; BCAS=behaviour therapy + post treatment therapy contact + aerobic exercise maintenance + social influence maintenance programme condition; F2F=face to face condition, FIPS=frequent in-person support condition; MIPS=minimal in-person support condition; Int=internet condition; PST=problem solving therapy condition; RPT=relapse prevention training condition; SF=skill focus condition, phone=telephone condition; WF=weight focus condition
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fig3: Fig 3 Mean difference in weight change at 12 months after initial weight loss in behavioural/lifestyle studies. BC=behaviour therapy + post-treatment therapy contact condition; BCA=behaviour therapy + post-treatment therapy contact + aerobic exercise maintenance condition; BCAS=behaviour therapy + post treatment therapy contact + aerobic exercise maintenance + social influence maintenance programme condition; F2F=face to face condition, FIPS=frequent in-person support condition; MIPS=minimal in-person support condition; Int=internet condition; PST=problem solving therapy condition; RPT=relapse prevention training condition; SF=skill focus condition, phone=telephone condition; WF=weight focus condition

Mentions: At 12 months, 15 behavioural/lifestyle studies including 25 comparisons202324363839404142434445464748 showed a mean difference in weight change of −1.56 kg (95% confidence interval −2.27 to −0.86 kg; I2=36%; fig 3).


Long term maintenance of weight loss with non-surgical interventions in obese adults: systematic review and meta-analyses of randomised controlled trials.

Dombrowski SU, Knittle K, Avenell A, Araújo-Soares V, Sniehotta FF - BMJ (2014)

Fig 3 Mean difference in weight change at 12 months after initial weight loss in behavioural/lifestyle studies. BC=behaviour therapy + post-treatment therapy contact condition; BCA=behaviour therapy + post-treatment therapy contact + aerobic exercise maintenance condition; BCAS=behaviour therapy + post treatment therapy contact + aerobic exercise maintenance + social influence maintenance programme condition; F2F=face to face condition, FIPS=frequent in-person support condition; MIPS=minimal in-person support condition; Int=internet condition; PST=problem solving therapy condition; RPT=relapse prevention training condition; SF=skill focus condition, phone=telephone condition; WF=weight focus condition
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4020585&req=5

fig3: Fig 3 Mean difference in weight change at 12 months after initial weight loss in behavioural/lifestyle studies. BC=behaviour therapy + post-treatment therapy contact condition; BCA=behaviour therapy + post-treatment therapy contact + aerobic exercise maintenance condition; BCAS=behaviour therapy + post treatment therapy contact + aerobic exercise maintenance + social influence maintenance programme condition; F2F=face to face condition, FIPS=frequent in-person support condition; MIPS=minimal in-person support condition; Int=internet condition; PST=problem solving therapy condition; RPT=relapse prevention training condition; SF=skill focus condition, phone=telephone condition; WF=weight focus condition
Mentions: At 12 months, 15 behavioural/lifestyle studies including 25 comparisons202324363839404142434445464748 showed a mean difference in weight change of −1.56 kg (95% confidence interval −2.27 to −0.86 kg; I2=36%; fig 3).

Bottom Line: Orlistat combined with behavioural interventions resulted in a -1.80 kg (-2.54 to -1.06; eight comparisons, 1738 participants) difference compared with placebo at 12 months.All orlistat studies reported higher frequencies of adverse gastrointestinal events in the experimental compared with placebo control groups.Behavioural interventions that deal with both diet and physical activity show small but significant benefits on weight loss maintenance.

View Article: PubMed Central - PubMed

Affiliation: Institute of Health and Society, Newcastle University, Baddiley-Clark Building, Newcastle upon Tyne NE2 4AX, UK School of Natural Sciences, University of Stirling, Cottrell Building, Stirling FK9 4LA, UK.

Show MeSH
Related in: MedlinePlus