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Childhood Adversities are Associated with Diabetes Management in Working Age in Finland.

Pisto L, Vadén A, Sillanmäki L, Mattila K - Int J Family Med (2014)

Bottom Line: No connection was found between childhood adversities and insulin use.Cumulative adversities did not markedly increase the association.Conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of General Practice, Medical School, University of Tampere, Lääkärinkatu 1, 33520 Tampere, Finland.

ABSTRACT
Backgrounds. Research findings suggest that the mind can cause physical disease. To plan the best quality of care, general practitioner needs to understand an individual's health problems in physical, social, and psychological dimensions. This study sought to establish whether adverse life events occurring in childhood and adolescence are associated with diabetes. Methods. The cohort was collected from the health and social support (HeSSup) study-a postal follow-up survey of randomized working-aged Finns initiated in 1998. The response rate was 40.0% and the final cohort size 24057. Data on reimbursed diabetes medication during the years 1998-2006 were obtained from the Social Insurance Institute of Finland registers. Subjects were divided into insulin, tablet, combination therapy, and drug-naive groups together with a control group without diabetes. The prevalence of childhood adversities was assessed based on answers to six survey questions. Results. Childhood adversities showed predominant linkage to diabetes type 2 groups, especially to the combination therapy group requiring combined insulin and tablet treatment. No connection was found between childhood adversities and insulin use. Cumulative adversities did not markedly increase the association. Conclusions. Stressful events in childhood are associated with diabetes combination therapy in working age. The meaning of the relationship remains unsolved.

No MeSH data available.


Related in: MedlinePlus

Flow chart illustrating the formation of study groups.
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Related In: Results  -  Collection


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fig1: Flow chart illustrating the formation of study groups.

Mentions: With the help of data from both the survey questionnaire and the SII registers, patients with diabetes were classified into five study groups (Figure 1), each patient with diabetes belonging to one group only. Those using only insulin medication (ATC code A10A) were classified into the insulin group (n = 190). It is likely that this group would be strongly weighted among those having diabetes type 1. People using oral diabetes medicine (ATC code A10B) were classified into the tablet group (n = 508) and consisted mostly of type 2 patients with diabetes. The third study group comprised those using both insulin (A10A) and tablet-form treatment (A10B) and was named as the combination therapy group (n = 188).


Childhood Adversities are Associated with Diabetes Management in Working Age in Finland.

Pisto L, Vadén A, Sillanmäki L, Mattila K - Int J Family Med (2014)

Flow chart illustrating the formation of study groups.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4020449&req=5

fig1: Flow chart illustrating the formation of study groups.
Mentions: With the help of data from both the survey questionnaire and the SII registers, patients with diabetes were classified into five study groups (Figure 1), each patient with diabetes belonging to one group only. Those using only insulin medication (ATC code A10A) were classified into the insulin group (n = 190). It is likely that this group would be strongly weighted among those having diabetes type 1. People using oral diabetes medicine (ATC code A10B) were classified into the tablet group (n = 508) and consisted mostly of type 2 patients with diabetes. The third study group comprised those using both insulin (A10A) and tablet-form treatment (A10B) and was named as the combination therapy group (n = 188).

Bottom Line: No connection was found between childhood adversities and insulin use.Cumulative adversities did not markedly increase the association.Conclusions.

View Article: PubMed Central - PubMed

Affiliation: Department of General Practice, Medical School, University of Tampere, Lääkärinkatu 1, 33520 Tampere, Finland.

ABSTRACT
Backgrounds. Research findings suggest that the mind can cause physical disease. To plan the best quality of care, general practitioner needs to understand an individual's health problems in physical, social, and psychological dimensions. This study sought to establish whether adverse life events occurring in childhood and adolescence are associated with diabetes. Methods. The cohort was collected from the health and social support (HeSSup) study-a postal follow-up survey of randomized working-aged Finns initiated in 1998. The response rate was 40.0% and the final cohort size 24057. Data on reimbursed diabetes medication during the years 1998-2006 were obtained from the Social Insurance Institute of Finland registers. Subjects were divided into insulin, tablet, combination therapy, and drug-naive groups together with a control group without diabetes. The prevalence of childhood adversities was assessed based on answers to six survey questions. Results. Childhood adversities showed predominant linkage to diabetes type 2 groups, especially to the combination therapy group requiring combined insulin and tablet treatment. No connection was found between childhood adversities and insulin use. Cumulative adversities did not markedly increase the association. Conclusions. Stressful events in childhood are associated with diabetes combination therapy in working age. The meaning of the relationship remains unsolved.

No MeSH data available.


Related in: MedlinePlus