Limits...
Human health risk analysis from disinfection by-products (DBPs) in drinking and bathing water of some Indian cities.

Mishra BK, Gupta SK, Sinha A - J Environ Health Sci Eng (2014)

Bottom Line: The corresponding lifetime cancer risk of the formed THMs to human beings was estimated by the USEPA and IRIS method as per Indian population.The total cancer risk reached 8.99 E-04 and 8.92 E-04 for males and females, respectively, the highest risk from THMs seems to be from the inhalation route followed by ingestion and dermal contacts.Results reveals that water containing THMs of the selected water treatment plant of the eastern part of India was unsafe in terms of risk evaluation through inhalation and ingestion, while dermal route of risk was found very close to permissible limit of USEPA.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Environmental Science and Engineering, Indian School of Mines, Dhanbad 826004, India.

ABSTRACT

Background: Human health risk assessment from exposure to disinfection by-products (DBPs) during drinking and bathing water vary from country to country as per life expectancy, body mass index, water consumption pattern and individual concentration of DBPs component, etc.

Methods: Present study considered average direct water intake per person for adult males and females as 4 & 3 L/day, respectively as per Indian literature for risk evaluation from another component of pollutant. While other important factor like average life expectancy, body weight & body surface area for male and female were considered 64 & 67 years, 51.9 & 45.4 Kg and 1.54 & 1.38 m(2) respectively as per Indian Council of Medical Research and WHO report. The corresponding lifetime cancer risk of the formed THMs to human beings was estimated by the USEPA and IRIS method as per Indian population.

Results: The total cancer risk reached 8.99 E-04 and 8.92 E-04 for males and females, respectively, the highest risk from THMs seems to be from the inhalation route followed by ingestion and dermal contacts.

Conclusions: The multipath way evaluations of lifetime cancer risks for THMs exposure through ingestion, dermal absorption, and inhalation exposure were examined at the highest degree of danger. Results reveals that water containing THMs of the selected water treatment plant of the eastern part of India was unsafe in terms of risk evaluation through inhalation and ingestion, while dermal route of risk was found very close to permissible limit of USEPA. Sensitivity analysis shows that every input parameter is sole responsible for total risk potential, whereas exposure duration playing important role for estimation of total risk.

No MeSH data available.


Related in: MedlinePlus

Route cancer risk for females from THMs in the drinking water.
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Figure 3: Route cancer risk for females from THMs in the drinking water.

Mentions: The potency factor of the all THMs that are linked up with lifetime cancer risk for the exposed individuals is changing from individual THMs. The cumulative cancer risk through ingestion route for THMs were found 3.18E-04 and 2.60E-04 for male and female respectively, which is 318 and 260 times more than the prescribed limit given by USEPA. The cancer risk through oral consumption is shown in Figures 2 and 3 for male and female respectively. The lifetime cancer risks from Chloroform was found maximum in supply water, which was found 1.81E-04 and 1.48E-04 for male and female respectively, which is 56% of total contributor in cancer risk through the ingestion system. This higher risk factor from chloroform revealed that the concentration of chloroform is much higher than the prescribed limit as per IS 10500 and USEPA. Researches also reported that chloroform made the highest percentage contribution to total risks [34,35].


Human health risk analysis from disinfection by-products (DBPs) in drinking and bathing water of some Indian cities.

Mishra BK, Gupta SK, Sinha A - J Environ Health Sci Eng (2014)

Route cancer risk for females from THMs in the drinking water.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4020354&req=5

Figure 3: Route cancer risk for females from THMs in the drinking water.
Mentions: The potency factor of the all THMs that are linked up with lifetime cancer risk for the exposed individuals is changing from individual THMs. The cumulative cancer risk through ingestion route for THMs were found 3.18E-04 and 2.60E-04 for male and female respectively, which is 318 and 260 times more than the prescribed limit given by USEPA. The cancer risk through oral consumption is shown in Figures 2 and 3 for male and female respectively. The lifetime cancer risks from Chloroform was found maximum in supply water, which was found 1.81E-04 and 1.48E-04 for male and female respectively, which is 56% of total contributor in cancer risk through the ingestion system. This higher risk factor from chloroform revealed that the concentration of chloroform is much higher than the prescribed limit as per IS 10500 and USEPA. Researches also reported that chloroform made the highest percentage contribution to total risks [34,35].

Bottom Line: The corresponding lifetime cancer risk of the formed THMs to human beings was estimated by the USEPA and IRIS method as per Indian population.The total cancer risk reached 8.99 E-04 and 8.92 E-04 for males and females, respectively, the highest risk from THMs seems to be from the inhalation route followed by ingestion and dermal contacts.Results reveals that water containing THMs of the selected water treatment plant of the eastern part of India was unsafe in terms of risk evaluation through inhalation and ingestion, while dermal route of risk was found very close to permissible limit of USEPA.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Environmental Science and Engineering, Indian School of Mines, Dhanbad 826004, India.

ABSTRACT

Background: Human health risk assessment from exposure to disinfection by-products (DBPs) during drinking and bathing water vary from country to country as per life expectancy, body mass index, water consumption pattern and individual concentration of DBPs component, etc.

Methods: Present study considered average direct water intake per person for adult males and females as 4 & 3 L/day, respectively as per Indian literature for risk evaluation from another component of pollutant. While other important factor like average life expectancy, body weight & body surface area for male and female were considered 64 & 67 years, 51.9 & 45.4 Kg and 1.54 & 1.38 m(2) respectively as per Indian Council of Medical Research and WHO report. The corresponding lifetime cancer risk of the formed THMs to human beings was estimated by the USEPA and IRIS method as per Indian population.

Results: The total cancer risk reached 8.99 E-04 and 8.92 E-04 for males and females, respectively, the highest risk from THMs seems to be from the inhalation route followed by ingestion and dermal contacts.

Conclusions: The multipath way evaluations of lifetime cancer risks for THMs exposure through ingestion, dermal absorption, and inhalation exposure were examined at the highest degree of danger. Results reveals that water containing THMs of the selected water treatment plant of the eastern part of India was unsafe in terms of risk evaluation through inhalation and ingestion, while dermal route of risk was found very close to permissible limit of USEPA. Sensitivity analysis shows that every input parameter is sole responsible for total risk potential, whereas exposure duration playing important role for estimation of total risk.

No MeSH data available.


Related in: MedlinePlus