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Papillary thyroid cancer and ulcerative colitis.

Casella G, Antonelli E, Di Bella C, Villanacci V, Rostami Nejad M, Baldini V, Bassotti G - Gastroenterol Hepatol Bed Bench (2013)

Bottom Line: Ulcerative colitis is associated with several malignancies.Here we report one such association, a rare one, with papillary thyroid carcinoma, and discuss the possible risk factors of such an association.

View Article: PubMed Central - PubMed

Affiliation: Division of Internal Medicine, Desio General Hospital, Italy.

ABSTRACT
Ulcerative colitis is associated with several malignancies. Here we report one such association, a rare one, with papillary thyroid carcinoma, and discuss the possible risk factors of such an association.

No MeSH data available.


Related in: MedlinePlus

A. Ultrasound appearance of right papillary thyroid carcinoma. B. Surgical specimen showing papillary thyroid carcinoma: complex and branching papillae, optical clear, with overlapping and grooved nuclei (hematoxylin and eosin, original magnification x20) C. Papillary carcinoma metastatic to a lymph node (hematoxylin and eosin, original magnification x4). D.Papillary thyroid carcinoma: vascular invasion (hematoxylin and eosin, original magnification x10)
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Figure 0001: A. Ultrasound appearance of right papillary thyroid carcinoma. B. Surgical specimen showing papillary thyroid carcinoma: complex and branching papillae, optical clear, with overlapping and grooved nuclei (hematoxylin and eosin, original magnification x20) C. Papillary carcinoma metastatic to a lymph node (hematoxylin and eosin, original magnification x4). D.Papillary thyroid carcinoma: vascular invasion (hematoxylin and eosin, original magnification x10)

Mentions: A 35 year old man was admitted in our department for a UC flare characterized by fever, abdominal pain and diarrhea associated to bloody stools; colonoscopy revealed severe pancolitis, confirmed by histology. The clinical picture gradually resolved after steroid treatment (prednisone 60 mg/day); mesalazine was started when tapering steroid therapy but it was stopped after some days due to abdominal pain associated to increased levels of pancreatic enzymes (amylase 160 U/L, normal upper value 100 U/L, lipase 160 U/L, normal upper value 60 U/L). Physical examination revealed a right thyroid nodule, confirmed by neck ultrasonography that showed a nodule 1.4 cm diameter with heterogeneous hypoechoic echogenic pattern associated with intra-parenchymal hyperechogenic microspots (Figure 1A). Cytological material obtained by ultrasound guided needle (25 gauge) aspiration revealed papillary thyroid carcinoma. Total thyroidectomy was performed; histological examination confirmed the diagnosis of papillary thyroid cancer (Figure 1B), also showing metastatic involvement in 5 out 13 latero-cervical lymph nodes removed and vascular invasion (Figures 1C and D). At present, the patient enjoys good health and is treated with salazopyrin, 1.5 g/day.


Papillary thyroid cancer and ulcerative colitis.

Casella G, Antonelli E, Di Bella C, Villanacci V, Rostami Nejad M, Baldini V, Bassotti G - Gastroenterol Hepatol Bed Bench (2013)

A. Ultrasound appearance of right papillary thyroid carcinoma. B. Surgical specimen showing papillary thyroid carcinoma: complex and branching papillae, optical clear, with overlapping and grooved nuclei (hematoxylin and eosin, original magnification x20) C. Papillary carcinoma metastatic to a lymph node (hematoxylin and eosin, original magnification x4). D.Papillary thyroid carcinoma: vascular invasion (hematoxylin and eosin, original magnification x10)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4017492&req=5

Figure 0001: A. Ultrasound appearance of right papillary thyroid carcinoma. B. Surgical specimen showing papillary thyroid carcinoma: complex and branching papillae, optical clear, with overlapping and grooved nuclei (hematoxylin and eosin, original magnification x20) C. Papillary carcinoma metastatic to a lymph node (hematoxylin and eosin, original magnification x4). D.Papillary thyroid carcinoma: vascular invasion (hematoxylin and eosin, original magnification x10)
Mentions: A 35 year old man was admitted in our department for a UC flare characterized by fever, abdominal pain and diarrhea associated to bloody stools; colonoscopy revealed severe pancolitis, confirmed by histology. The clinical picture gradually resolved after steroid treatment (prednisone 60 mg/day); mesalazine was started when tapering steroid therapy but it was stopped after some days due to abdominal pain associated to increased levels of pancreatic enzymes (amylase 160 U/L, normal upper value 100 U/L, lipase 160 U/L, normal upper value 60 U/L). Physical examination revealed a right thyroid nodule, confirmed by neck ultrasonography that showed a nodule 1.4 cm diameter with heterogeneous hypoechoic echogenic pattern associated with intra-parenchymal hyperechogenic microspots (Figure 1A). Cytological material obtained by ultrasound guided needle (25 gauge) aspiration revealed papillary thyroid carcinoma. Total thyroidectomy was performed; histological examination confirmed the diagnosis of papillary thyroid cancer (Figure 1B), also showing metastatic involvement in 5 out 13 latero-cervical lymph nodes removed and vascular invasion (Figures 1C and D). At present, the patient enjoys good health and is treated with salazopyrin, 1.5 g/day.

Bottom Line: Ulcerative colitis is associated with several malignancies.Here we report one such association, a rare one, with papillary thyroid carcinoma, and discuss the possible risk factors of such an association.

View Article: PubMed Central - PubMed

Affiliation: Division of Internal Medicine, Desio General Hospital, Italy.

ABSTRACT
Ulcerative colitis is associated with several malignancies. Here we report one such association, a rare one, with papillary thyroid carcinoma, and discuss the possible risk factors of such an association.

No MeSH data available.


Related in: MedlinePlus