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Effect of essential oil of Rosa Damascena on human colon cancer cell line SW742.

Rezaie-Tavirani M, Fayazfar S, Heydari-Keshel S, Rezaee MB, Zamanian-Azodi M, Rezaei-Tavirani M, Khodarahmi R - Gastroenterol Hepatol Bed Bench (2013)

Bottom Line: The essential oil of Rosa Damascena was obtained by distillation and its effect on SW742 cell-line and fibroblast cells were investigated with cell culture.This study showed that soluble part of Rosa Damascena oil increases cell proliferation in high volumes and the non-soluble component decreases cell proliferation.The effects of essential oils, such as Rosa Damascena, on cell proliferation require more thorough investigation.

View Article: PubMed Central - PubMed

Affiliation: Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT

Aim: In this study, we report the effect of the essential oil of Rosa Damascena on human colon cancer cell line (SW742) and human fibroblast cells.

Background: Colon cancer is the second most common fatal malignancy. Owing to the existence of many side effects and problems related to common treatments such as surgery, chemotherapy and radiotherapy, alternative treatments are being investigated. Some herbal medicines have shown promising results against different types of cancers. Herbal medicines used have included the use naturally occurring essential oils.

Patients and methods: The essential oil of Rosa Damascena was obtained by distillation and its effect on SW742 cell-line and fibroblast cells were investigated with cell culture. The cells were cultured and different volumes of essential oil were induced to the cells. After48hincubation, cell survival was measured and using statistical analysis, the findings were evaluated and reported.

Results: This study showed that soluble part of Rosa Damascena oil increases cell proliferation in high volumes and the non-soluble component decreases cell proliferation.

Conclusion: The effects of essential oils, such as Rosa Damascena, on cell proliferation require more thorough investigation.

No MeSH data available.


Related in: MedlinePlus

SW742 cell survival in the presence of different volumes of herbalessential oil after 48h incubation time using MTT assay.Cells populations that are cultured in another plate in the absence of essential oil are used as outer control.All amounts are different from control (P value ≤ 0.001).
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Figure 0003: SW742 cell survival in the presence of different volumes of herbalessential oil after 48h incubation time using MTT assay.Cells populations that are cultured in another plate in the absence of essential oil are used as outer control.All amounts are different from control (P value ≤ 0.001).

Mentions: From Figures 3 and 4 it can be inferred that survival percentage of cancer and normal cells in presence of various volumes of essential oil (control, 0, 1, 2, 3, 4, 5 and 10 µl) after 48h incubation using MTT method has been presented. For better understanding the data that are presented in Figures 3 and 4 are plotted again without outer control in Figures 5 and 6.


Effect of essential oil of Rosa Damascena on human colon cancer cell line SW742.

Rezaie-Tavirani M, Fayazfar S, Heydari-Keshel S, Rezaee MB, Zamanian-Azodi M, Rezaei-Tavirani M, Khodarahmi R - Gastroenterol Hepatol Bed Bench (2013)

SW742 cell survival in the presence of different volumes of herbalessential oil after 48h incubation time using MTT assay.Cells populations that are cultured in another plate in the absence of essential oil are used as outer control.All amounts are different from control (P value ≤ 0.001).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4017490&req=5

Figure 0003: SW742 cell survival in the presence of different volumes of herbalessential oil after 48h incubation time using MTT assay.Cells populations that are cultured in another plate in the absence of essential oil are used as outer control.All amounts are different from control (P value ≤ 0.001).
Mentions: From Figures 3 and 4 it can be inferred that survival percentage of cancer and normal cells in presence of various volumes of essential oil (control, 0, 1, 2, 3, 4, 5 and 10 µl) after 48h incubation using MTT method has been presented. For better understanding the data that are presented in Figures 3 and 4 are plotted again without outer control in Figures 5 and 6.

Bottom Line: The essential oil of Rosa Damascena was obtained by distillation and its effect on SW742 cell-line and fibroblast cells were investigated with cell culture.This study showed that soluble part of Rosa Damascena oil increases cell proliferation in high volumes and the non-soluble component decreases cell proliferation.The effects of essential oils, such as Rosa Damascena, on cell proliferation require more thorough investigation.

View Article: PubMed Central - PubMed

Affiliation: Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT

Aim: In this study, we report the effect of the essential oil of Rosa Damascena on human colon cancer cell line (SW742) and human fibroblast cells.

Background: Colon cancer is the second most common fatal malignancy. Owing to the existence of many side effects and problems related to common treatments such as surgery, chemotherapy and radiotherapy, alternative treatments are being investigated. Some herbal medicines have shown promising results against different types of cancers. Herbal medicines used have included the use naturally occurring essential oils.

Patients and methods: The essential oil of Rosa Damascena was obtained by distillation and its effect on SW742 cell-line and fibroblast cells were investigated with cell culture. The cells were cultured and different volumes of essential oil were induced to the cells. After48hincubation, cell survival was measured and using statistical analysis, the findings were evaluated and reported.

Results: This study showed that soluble part of Rosa Damascena oil increases cell proliferation in high volumes and the non-soluble component decreases cell proliferation.

Conclusion: The effects of essential oils, such as Rosa Damascena, on cell proliferation require more thorough investigation.

No MeSH data available.


Related in: MedlinePlus