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Duodenal adenocarcinoma might be the cause of intractable nausea and vomiting in patient with coeliac disease.

Rajabalinia H, Dabiri R, Shahbazi S, Ghobakhlou M, Bahreiny R, Molaei M, Rostami Nejad M, Fatemi SR - Gastroenterol Hepatol Bed Bench (2012)

Bottom Line: Subsequently, a duodenal segment resection was performed.After surgery, the patient recovered well and left our hospital in good condition.Clinicians should take into small bowel adenocarcinoma is rare but associated with CD particularly in CD patients with worrying symptoms such as nausea and vomiting unresponsiveness to treatment and these patients should be screened for long term complications like malignancy.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology and Liver diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Coeliac disease (CD) is an autoimmune disorder which leads to chronic inflammation of the gut. Untreated CD is associated with upper gastrointestinal malignancies, Small-bowel lymphoma and adenocarcinoma are recognized complications of untreated coeliac disease (CD). We report the case of a 43-year-old male suffering from CD who was treated with a gluten-free diet one year, presenting with complaints of intractable nausea and vomiting. After several studies, He underwent push enteroscopy, which identified one large mass lesion in the third part of duodenum. However, histopathological examination showed adenocarcinoma. Subsequently, a duodenal segment resection was performed. After surgery, the patient recovered well and left our hospital in good condition. Clinicians should take into small bowel adenocarcinoma is rare but associated with CD particularly in CD patients with worrying symptoms such as nausea and vomiting unresponsiveness to treatment and these patients should be screened for long term complications like malignancy.

No MeSH data available.


Related in: MedlinePlus

Mild atrophic folds and scalloping in D2
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Figure 0001: Mild atrophic folds and scalloping in D2

Mentions: A 43-year-old man with intractable nausea and vomiting 2-3 hours after eating and anemia had been worked up. In primary evaluation laboratory data showed: Hemoglobin = 11.2g/dl, MCV = 72.8fl, Serum Iron = 23micg/dl, Ferritin = 10.3ng/ml, Stool exam: Occult blood , Anti-Tissue-Transglutaminase IgA = 26.5(+), Esophagogastroduodenoscopy (EGD): Mild antral gastritis, Mild atrophic folds + scalloping in the second part of duodenum (D2) (Figure 1).


Duodenal adenocarcinoma might be the cause of intractable nausea and vomiting in patient with coeliac disease.

Rajabalinia H, Dabiri R, Shahbazi S, Ghobakhlou M, Bahreiny R, Molaei M, Rostami Nejad M, Fatemi SR - Gastroenterol Hepatol Bed Bench (2012)

Mild atrophic folds and scalloping in D2
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4017469&req=5

Figure 0001: Mild atrophic folds and scalloping in D2
Mentions: A 43-year-old man with intractable nausea and vomiting 2-3 hours after eating and anemia had been worked up. In primary evaluation laboratory data showed: Hemoglobin = 11.2g/dl, MCV = 72.8fl, Serum Iron = 23micg/dl, Ferritin = 10.3ng/ml, Stool exam: Occult blood , Anti-Tissue-Transglutaminase IgA = 26.5(+), Esophagogastroduodenoscopy (EGD): Mild antral gastritis, Mild atrophic folds + scalloping in the second part of duodenum (D2) (Figure 1).

Bottom Line: Subsequently, a duodenal segment resection was performed.After surgery, the patient recovered well and left our hospital in good condition.Clinicians should take into small bowel adenocarcinoma is rare but associated with CD particularly in CD patients with worrying symptoms such as nausea and vomiting unresponsiveness to treatment and these patients should be screened for long term complications like malignancy.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology and Liver diseases Research center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

ABSTRACT
Coeliac disease (CD) is an autoimmune disorder which leads to chronic inflammation of the gut. Untreated CD is associated with upper gastrointestinal malignancies, Small-bowel lymphoma and adenocarcinoma are recognized complications of untreated coeliac disease (CD). We report the case of a 43-year-old male suffering from CD who was treated with a gluten-free diet one year, presenting with complaints of intractable nausea and vomiting. After several studies, He underwent push enteroscopy, which identified one large mass lesion in the third part of duodenum. However, histopathological examination showed adenocarcinoma. Subsequently, a duodenal segment resection was performed. After surgery, the patient recovered well and left our hospital in good condition. Clinicians should take into small bowel adenocarcinoma is rare but associated with CD particularly in CD patients with worrying symptoms such as nausea and vomiting unresponsiveness to treatment and these patients should be screened for long term complications like malignancy.

No MeSH data available.


Related in: MedlinePlus