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Fetomaternal outcome in severe preeclamptic women undergoing emergency cesarean section under either general or spinal anesthesia.

Chattopadhyay S, Das A, Pahari S - J Pregnancy (2014)

Bottom Line: Significantly more neonates of patients receiving GA were found to be preterm (77.8% versus 44.5%; P < 0.01) and required advanced resuscitation.To conclude, severe preeclamptic mothers receiving general anesthesia and their babies required more critical care support.Maternal as well as neonatal mortality was significantly higher with general anesthesia.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesiology, Medical College & Hospital, 88 College Street, Kolkata 700073, India ; BC 103, Salt Lake, Kolkata 700064, India.

ABSTRACT
This prospective observational study compared the effects of general and spinal anesthesia in 173 severe preeclamptic women undergoing emergency cesarean section. 146 (84.5%) patients underwent spinal anesthesia (SA) and 27 (15.5%) patients had general anesthesia (GA). Most of the patients were primigravid and iparous. Intraoperatively SA group required more intravenous fluid and vasopressor support, while GA group required more preoperative labetalol injection for blood pressure control. Overall 13.3% of patients required critical care, particularly GA group (44.4% versus 7.5%; P < 0.001). Patients receiving GA had a higher mortality (25.9% versus 1.4%; P < 0.001). The length of hospital stay was comparable. Significantly more neonates of patients receiving GA were found to be preterm (77.8% versus 44.5%; P < 0.01) and required advanced resuscitation. GA group also had higher neonatal mortality (29.6% versus 11%; P < 0.05). To conclude, severe preeclamptic mothers receiving general anesthesia and their babies required more critical care support. Maternal as well as neonatal mortality was significantly higher with general anesthesia.

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Related in: MedlinePlus

Fetal mortality comparisons. GA was associated with higher fetal deaths.
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Related In: Results  -  Collection


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fig3: Fetal mortality comparisons. GA was associated with higher fetal deaths.

Mentions: Of all the 24 babies who died 8 (29.6%) were from the GA group and 16 (11%) were from the spinal group. Intergroup comparison shows that fetal mortality was significantly higher in GA group (P < 0.01), Figure 3.


Fetomaternal outcome in severe preeclamptic women undergoing emergency cesarean section under either general or spinal anesthesia.

Chattopadhyay S, Das A, Pahari S - J Pregnancy (2014)

Fetal mortality comparisons. GA was associated with higher fetal deaths.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4016895&req=5

fig3: Fetal mortality comparisons. GA was associated with higher fetal deaths.
Mentions: Of all the 24 babies who died 8 (29.6%) were from the GA group and 16 (11%) were from the spinal group. Intergroup comparison shows that fetal mortality was significantly higher in GA group (P < 0.01), Figure 3.

Bottom Line: Significantly more neonates of patients receiving GA were found to be preterm (77.8% versus 44.5%; P < 0.01) and required advanced resuscitation.To conclude, severe preeclamptic mothers receiving general anesthesia and their babies required more critical care support.Maternal as well as neonatal mortality was significantly higher with general anesthesia.

View Article: PubMed Central - PubMed

Affiliation: Department of Anaesthesiology, Medical College & Hospital, 88 College Street, Kolkata 700073, India ; BC 103, Salt Lake, Kolkata 700064, India.

ABSTRACT
This prospective observational study compared the effects of general and spinal anesthesia in 173 severe preeclamptic women undergoing emergency cesarean section. 146 (84.5%) patients underwent spinal anesthesia (SA) and 27 (15.5%) patients had general anesthesia (GA). Most of the patients were primigravid and iparous. Intraoperatively SA group required more intravenous fluid and vasopressor support, while GA group required more preoperative labetalol injection for blood pressure control. Overall 13.3% of patients required critical care, particularly GA group (44.4% versus 7.5%; P < 0.001). Patients receiving GA had a higher mortality (25.9% versus 1.4%; P < 0.001). The length of hospital stay was comparable. Significantly more neonates of patients receiving GA were found to be preterm (77.8% versus 44.5%; P < 0.01) and required advanced resuscitation. GA group also had higher neonatal mortality (29.6% versus 11%; P < 0.05). To conclude, severe preeclamptic mothers receiving general anesthesia and their babies required more critical care support. Maternal as well as neonatal mortality was significantly higher with general anesthesia.

Show MeSH
Related in: MedlinePlus