Limits...
Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.

Carvajal-Zarrabal O, Nolasco-Hipolito C, Aguilar-Uscanga MG, Melo Santiesteban G, Hayward-Jones PM, Barradas-Dermitz DM - Biomed Res Int (2014)

Bottom Line: We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats.In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels.AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors.

View Article: PubMed Central - PubMed

Affiliation: Biochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, VER., Mexico.

ABSTRACT
Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α -amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.

Show MeSH

Related in: MedlinePlus

Blood serum profile levels of liver function markers in rats fed with different oil diets: a) GOT; b) GPT; c) Alkaline phosphatase; d) Cholinesterase; e) α-amylase. Corn-canola diet (CG group, n = 5); corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase. Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4016882&req=5

fig2: Blood serum profile levels of liver function markers in rats fed with different oil diets: a) GOT; b) GPT; c) Alkaline phosphatase; d) Cholinesterase; e) α-amylase. Corn-canola diet (CG group, n = 5); corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase. Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.

Mentions: The effect of dietary olive and avocado oils on pancreatic function indicators is shown in Figure 2. Levels of glutamic oxaloacetic transaminase (GOT) in S-AOC and S-AOS groups were similar and not significantly different than either the S or CG group. Significantly lower levels were observed in the S-OO group (P < 0.05) in comparison with all the groups in the study. In the cases of glutamic pyruvic transaminase (GPT) and alkaline phosphatase (ALP), no significant results were observed among the study groups. The S-AOS group showed similar, nonsignificant values for cholinesterase in comparison with CG. In contrast, S and S-AOC groups both presented significantly lower results (P < 0.05), but in the case of S-OO group these levels decreased in a highly significant manner (P < 0.01) when compared to CG and S-AOS. Levels of α-amylase were all similar for S, S-OO, S-AOC, and S-AOS groups; however, when compared to control group CG, the results were all very significantly higher (P < 0.01).


Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.

Carvajal-Zarrabal O, Nolasco-Hipolito C, Aguilar-Uscanga MG, Melo Santiesteban G, Hayward-Jones PM, Barradas-Dermitz DM - Biomed Res Int (2014)

Blood serum profile levels of liver function markers in rats fed with different oil diets: a) GOT; b) GPT; c) Alkaline phosphatase; d) Cholinesterase; e) α-amylase. Corn-canola diet (CG group, n = 5); corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase. Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4016882&req=5

fig2: Blood serum profile levels of liver function markers in rats fed with different oil diets: a) GOT; b) GPT; c) Alkaline phosphatase; d) Cholinesterase; e) α-amylase. Corn-canola diet (CG group, n = 5); corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase. Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
Mentions: The effect of dietary olive and avocado oils on pancreatic function indicators is shown in Figure 2. Levels of glutamic oxaloacetic transaminase (GOT) in S-AOC and S-AOS groups were similar and not significantly different than either the S or CG group. Significantly lower levels were observed in the S-OO group (P < 0.05) in comparison with all the groups in the study. In the cases of glutamic pyruvic transaminase (GPT) and alkaline phosphatase (ALP), no significant results were observed among the study groups. The S-AOS group showed similar, nonsignificant values for cholinesterase in comparison with CG. In contrast, S and S-AOC groups both presented significantly lower results (P < 0.05), but in the case of S-OO group these levels decreased in a highly significant manner (P < 0.01) when compared to CG and S-AOS. Levels of α-amylase were all similar for S, S-OO, S-AOC, and S-AOS groups; however, when compared to control group CG, the results were all very significantly higher (P < 0.01).

Bottom Line: We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats.In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels.AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors.

View Article: PubMed Central - PubMed

Affiliation: Biochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, VER., Mexico.

ABSTRACT
Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α -amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.

Show MeSH
Related in: MedlinePlus