Limits...
Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.

Carvajal-Zarrabal O, Nolasco-Hipolito C, Aguilar-Uscanga MG, Melo Santiesteban G, Hayward-Jones PM, Barradas-Dermitz DM - Biomed Res Int (2014)

Bottom Line: We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats.In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels.AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors.

View Article: PubMed Central - PubMed

Affiliation: Biochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, VER., Mexico.

ABSTRACT
Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α -amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.

Show MeSH

Related in: MedlinePlus

Blood serum profile levels of liver function markers in rats fed with different oil diets: a) total protein; b) albumin; c) globulin; d) direct bilirubin. Corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4016882&req=5

fig1: Blood serum profile levels of liver function markers in rats fed with different oil diets: a) total protein; b) albumin; c) globulin; d) direct bilirubin. Corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.

Mentions: The effect of olive and avocado oils on liver function indicators is shown in Figure 1. S, S-OO, S-AOC, and S-AOS study groups showed changes in total protein levels, all of them significantly higher (P < 0.05) than control group (CG). Additionally, direct bilirubin levels in S-OO and S-AOC groups decreased (P < 0.05) in relation to CG and S groups, but not for the S-AOS group, where a nonsignificant decrease was observed. Albumin and globulin levels in S-OO, S-AOC, and S-AOS study groups were not found to be significantly different either from S or CG groups.


Effect of dietary intake of avocado oil and olive oil on biochemical markers of liver function in sucrose-fed rats.

Carvajal-Zarrabal O, Nolasco-Hipolito C, Aguilar-Uscanga MG, Melo Santiesteban G, Hayward-Jones PM, Barradas-Dermitz DM - Biomed Res Int (2014)

Blood serum profile levels of liver function markers in rats fed with different oil diets: a) total protein; b) albumin; c) globulin; d) direct bilirubin. Corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4016882&req=5

fig1: Blood serum profile levels of liver function markers in rats fed with different oil diets: a) total protein; b) albumin; c) globulin; d) direct bilirubin. Corn-canola diet plus 30% sucrose in drinking water (S group, n = 5); olive oil diet plus 30% sucrose in drinking water (S-OO group, n = 5); avocado oil diet extracted by centrifugation plus 30% sucrose in drinking water (S-AOC group, n = 5); avocado oil diet extracted by solvent plus 30% sucrose in drinking water (S-AOS group, n = 5). Values are mean ± SD. *P < 0.05; **P < 0.01 versus corresponding data in CG group.
Mentions: The effect of olive and avocado oils on liver function indicators is shown in Figure 1. S, S-OO, S-AOC, and S-AOS study groups showed changes in total protein levels, all of them significantly higher (P < 0.05) than control group (CG). Additionally, direct bilirubin levels in S-OO and S-AOC groups decreased (P < 0.05) in relation to CG and S groups, but not for the S-AOS group, where a nonsignificant decrease was observed. Albumin and globulin levels in S-OO, S-AOC, and S-AOS study groups were not found to be significantly different either from S or CG groups.

Bottom Line: We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats.In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels.AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors.

View Article: PubMed Central - PubMed

Affiliation: Biochemical and Nutrition Chemistry Area, University of Veracruz, SS Juan Pablo II s/n, 94294 Boca del Río, VER., Mexico.

ABSTRACT
Metabolic changes, along with cardiovascular and hepatic factors, are associated with the development of diseases such as diabetes, dyslipidemia, and obesity. We evaluated the effect of avocado oil supplementation (centrifuged and solvent extracted), compared with olive oil, upon the hepatic function in sucrose-fed rats. Twenty-five rats were divided into five groups: control (basal diet), a sucrose-fed group (basal diet plus 30% sucrose solution), and three other groups (S-OO, S-AOC, and S-AOS, indicating basal diet plus 30% sucrose solution plus olive oil OO, avocado oil extracted by centrifugation AOC or using solvent AOS, resp.). Glucose, total cholesterol, triglycerides, total protein, albumin, globulin, direct bilirubin, glutamic pyruvic transaminase, glutamic oxaloacetic transaminase, alkaline phosphatase, cholinesterase, and α -amylase concentrations were determined and avocado oil effect on them was studied. In some cases the induced metabolic alteration significantly affected total protein and bilirubin levels and also had a highly significant effect on α -amylase levels. AOC and AOS exhibited effects similar to those of olive oil, according to the nonsignificant difference in fatty acid profile observed by other authors. Avocado oil consumption could be beneficial in the control of altered metabolic profile illnesses as it presents effects on hepatic function biochemical markers similar to olive oil.

Show MeSH
Related in: MedlinePlus