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A rare presentation of lymphoma of the cervix with cross-sectional imaging correlation.

Korivi BR, Jensen CT, Patnana M, Patel KP, Bathala TK - Case Rep Radiol (2014)

Bottom Line: Non-Hodgkin's lymphoma of the cervix is an extremely uncommon entity, with no standard established treatment protocol.A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT).She then underwent radiation to the cervix with significant improvement in the cervical lymphoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, Houston, TX 77030-4009, USA.

ABSTRACT
Non-Hodgkin's lymphoma of the cervix is an extremely uncommon entity, with no standard established treatment protocol. A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT). It was further evaluated with ultrasound, biopsy, and positron emission tomography-computed tomography (PET-CT), which demonstrated a growing biopsy-proven lymphomatous mass and new humeral head lesion. The patient was started on chemotherapy to control the newly diagnosed humeral head lesion, which then regressed. She then underwent radiation to the cervix with significant improvement in the cervical lymphoma. A review of cross-sectional imaging findings of lymphoma of the cervix is provided, including how to differentiate it from other more common diseases of the cervix. Clinical awareness of rare cervical masses such as lymphoma is very important in order to achieve timely diagnosis and appropriate treatment.

No MeSH data available.


Related in: MedlinePlus

Axial PET-CT fusion image demonstrates an FDG-avid lesion in the left humeral head, consistent with a metastasis, labeled with an arrow (a). Postchemotherapy PET-CT axial image obtained just a few months later demonstrates complete metabolic response to the left humeral head lesion, labelled with an arrow (b).
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fig4: Axial PET-CT fusion image demonstrates an FDG-avid lesion in the left humeral head, consistent with a metastasis, labeled with an arrow (a). Postchemotherapy PET-CT axial image obtained just a few months later demonstrates complete metabolic response to the left humeral head lesion, labelled with an arrow (b).

Mentions: A PET-CT obtained 10 days later again demonstrated the new metastatic lesion in the left humeral head (Figure 4(a)). It also depicted the large biopsy-proven lymphomatous cervical mass which had grown since the CT to 8.4 × 5.3 cm, with a maximum standard uptake value (SUV) of 20.7 (Figures 5(a) and 5(b)).


A rare presentation of lymphoma of the cervix with cross-sectional imaging correlation.

Korivi BR, Jensen CT, Patnana M, Patel KP, Bathala TK - Case Rep Radiol (2014)

Axial PET-CT fusion image demonstrates an FDG-avid lesion in the left humeral head, consistent with a metastasis, labeled with an arrow (a). Postchemotherapy PET-CT axial image obtained just a few months later demonstrates complete metabolic response to the left humeral head lesion, labelled with an arrow (b).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4016868&req=5

fig4: Axial PET-CT fusion image demonstrates an FDG-avid lesion in the left humeral head, consistent with a metastasis, labeled with an arrow (a). Postchemotherapy PET-CT axial image obtained just a few months later demonstrates complete metabolic response to the left humeral head lesion, labelled with an arrow (b).
Mentions: A PET-CT obtained 10 days later again demonstrated the new metastatic lesion in the left humeral head (Figure 4(a)). It also depicted the large biopsy-proven lymphomatous cervical mass which had grown since the CT to 8.4 × 5.3 cm, with a maximum standard uptake value (SUV) of 20.7 (Figures 5(a) and 5(b)).

Bottom Line: Non-Hodgkin's lymphoma of the cervix is an extremely uncommon entity, with no standard established treatment protocol.A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT).She then underwent radiation to the cervix with significant improvement in the cervical lymphoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Pickens Academic Tower, 1400 Pressler Street, Unit 1473, Houston, TX 77030-4009, USA.

ABSTRACT
Non-Hodgkin's lymphoma of the cervix is an extremely uncommon entity, with no standard established treatment protocol. A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT). It was further evaluated with ultrasound, biopsy, and positron emission tomography-computed tomography (PET-CT), which demonstrated a growing biopsy-proven lymphomatous mass and new humeral head lesion. The patient was started on chemotherapy to control the newly diagnosed humeral head lesion, which then regressed. She then underwent radiation to the cervix with significant improvement in the cervical lymphoma. A review of cross-sectional imaging findings of lymphoma of the cervix is provided, including how to differentiate it from other more common diseases of the cervix. Clinical awareness of rare cervical masses such as lymphoma is very important in order to achieve timely diagnosis and appropriate treatment.

No MeSH data available.


Related in: MedlinePlus