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Biosynthesis and Antimicrobial Activity of Semiconductor Nanoparticles against Oral Pathogens.

Malarkodi C, Rajeshkumar S, Paulkumar K, Vanaja M, Gnanajobitha G, Annadurai G - Bioinorg Chem Appl (2014)

Bottom Line: The results indicated that the proteins, which contain amine groups, played a reducing and controlling responsibility during the formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles in the colloidal solution.Staphylococcus sp.Lactobacillus sp., and Candida albicans and these results confirmed that the sulphide nanoparticles are exhibiting good bactericidal activity.

View Article: PubMed Central - PubMed

Affiliation: Environmental Nanotechnology Division, Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamilnadu 627412, India.

ABSTRACT
Dental care is an essential phenomenon in human health. Oral pathogens can cause severe break which may show the way to serious issues in human disease like blood circulation and coronary disease. In the current study, we demonstrated the synthesis and antimicrobial activity of cadmium sulphide and zinc sulphide nanoparticles against oral pathogens. The process for the synthesis of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles is fast, novel, and ecofriendly. Formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was confirmed by surface plasmon spectra using UV-Vis spectrophotometer. The morphology of crystalline phase of nanoparticles was determined from transmission electron microscopy (TEM) and X-ray diffraction (XRD) spectra. The average size of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was in the range of 10 nm to 25 nm and 65 nm, respectively, and the observed morphology was spherical. The results indicated that the proteins, which contain amine groups, played a reducing and controlling responsibility during the formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles in the colloidal solution. The antimicrobial activity was assessed against oral pathogens such as Streptococcus sp. Staphylococcus sp. Lactobacillus sp., and Candida albicans and these results confirmed that the sulphide nanoparticles are exhibiting good bactericidal activity.

No MeSH data available.


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Fluorescence image of (a) CdS nanoparticles and (b) ZnS nanoparticles synthesized from K. pneumoniae.
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fig7: Fluorescence image of (a) CdS nanoparticles and (b) ZnS nanoparticles synthesized from K. pneumoniae.

Mentions: CdS and ZnS also known as colloidal semiconductor nanocrystals are novel inorganic fluorescence labeling agents [44, 45]. The results obtained clearly exhibit the fluorescent intensity of CdS and ZnS nanoparticles. Figures 7(a) and 7(b) show the characteristic “green” and “red” fluorescence image of CdS nanoparticle in aqueous colloidal solution excited by laser source at 442 nm. Figures 7(c) and 7(d) represent the image of synthesized ZnS nanoparticles with a bright green fluorescence when exposed to ultraviolet radiation.The results have given support for considering this novel system based on CdS to be potentially used in biolabeling applications. Mansur et al. [46] suggest that synthesis of CdS and ZnS nanocrystals represents hybrid inorganic-organic materials that can be both fabricated and functionalized with biomolecules in a relative facile synthetic route. In the present study, the synthesis of semiconductor nanoparticles opens a wide window of possibilities in biomedical research and applications for producing water soluble inorganic fluorophores based on quantum dots.


Biosynthesis and Antimicrobial Activity of Semiconductor Nanoparticles against Oral Pathogens.

Malarkodi C, Rajeshkumar S, Paulkumar K, Vanaja M, Gnanajobitha G, Annadurai G - Bioinorg Chem Appl (2014)

Fluorescence image of (a) CdS nanoparticles and (b) ZnS nanoparticles synthesized from K. pneumoniae.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4016845&req=5

fig7: Fluorescence image of (a) CdS nanoparticles and (b) ZnS nanoparticles synthesized from K. pneumoniae.
Mentions: CdS and ZnS also known as colloidal semiconductor nanocrystals are novel inorganic fluorescence labeling agents [44, 45]. The results obtained clearly exhibit the fluorescent intensity of CdS and ZnS nanoparticles. Figures 7(a) and 7(b) show the characteristic “green” and “red” fluorescence image of CdS nanoparticle in aqueous colloidal solution excited by laser source at 442 nm. Figures 7(c) and 7(d) represent the image of synthesized ZnS nanoparticles with a bright green fluorescence when exposed to ultraviolet radiation.The results have given support for considering this novel system based on CdS to be potentially used in biolabeling applications. Mansur et al. [46] suggest that synthesis of CdS and ZnS nanocrystals represents hybrid inorganic-organic materials that can be both fabricated and functionalized with biomolecules in a relative facile synthetic route. In the present study, the synthesis of semiconductor nanoparticles opens a wide window of possibilities in biomedical research and applications for producing water soluble inorganic fluorophores based on quantum dots.

Bottom Line: The results indicated that the proteins, which contain amine groups, played a reducing and controlling responsibility during the formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles in the colloidal solution.Staphylococcus sp.Lactobacillus sp., and Candida albicans and these results confirmed that the sulphide nanoparticles are exhibiting good bactericidal activity.

View Article: PubMed Central - PubMed

Affiliation: Environmental Nanotechnology Division, Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamilnadu 627412, India.

ABSTRACT
Dental care is an essential phenomenon in human health. Oral pathogens can cause severe break which may show the way to serious issues in human disease like blood circulation and coronary disease. In the current study, we demonstrated the synthesis and antimicrobial activity of cadmium sulphide and zinc sulphide nanoparticles against oral pathogens. The process for the synthesis of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles is fast, novel, and ecofriendly. Formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was confirmed by surface plasmon spectra using UV-Vis spectrophotometer. The morphology of crystalline phase of nanoparticles was determined from transmission electron microscopy (TEM) and X-ray diffraction (XRD) spectra. The average size of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles was in the range of 10 nm to 25 nm and 65 nm, respectively, and the observed morphology was spherical. The results indicated that the proteins, which contain amine groups, played a reducing and controlling responsibility during the formation of cadmium sulphide (CdS) and zinc sulphide (ZnS) nanoparticles in the colloidal solution. The antimicrobial activity was assessed against oral pathogens such as Streptococcus sp. Staphylococcus sp. Lactobacillus sp., and Candida albicans and these results confirmed that the sulphide nanoparticles are exhibiting good bactericidal activity.

No MeSH data available.


Related in: MedlinePlus