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Updating the evidence for the effect of radiofrequency catheter ablation on left atrial volume and function in patients with atrial fibrillation: a meta-analysis.

Zhuang Y, Yong YH, Chen ML - JRSM Open (2014)

Bottom Line: LA ejection fraction/LA active emptying fraction did not decrease in patients without AF recurrence, whereas they decreased in patients with AF recurrence.As for LA strain, it seems that LA strain increases in patients without AF recurrence, with less fibrosis and with more LA volumes decrease, but the differences were not significant.Successful RFCA in patients with AF significantly decreases LA size and volumes and does not seem to adversely affect LA function.

View Article: PubMed Central - PubMed

Affiliation: Intensive Care Unit, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China.

ABSTRACT

Objectives: To systematically review the effects of radiofrequency catheter ablation (RFCA) on left atrial (LA) size, volumes and function in patients with atrial fibrillation (AF).

Methods: We searched MEDLINE, EMBASE, ScienceDirect, Highwire, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and the reference lists of retrieved reports in July 2012.

Setting: China.

Participants: Twenty-six studies (enrolling 1821 patients) were included in the final analysis.

Main outcome measures: Changes of LA size or volumes and/or function in patients with AF after RFCA.

Results: Compared to pre-ablation values, there were significant decreases in LA diameter and LA volumes at post-ablation follow-up. However, compared to pre-ablation values, there were no significant differences in LA ejection fraction/LA active emptying fraction and LA strain at post-ablation follow-up. Decreases in LA diameter and LA volumes remained significant in those without AF recurrence but not in those with AF recurrence. LA ejection fraction/LA active emptying fraction did not decrease in patients without AF recurrence, whereas they decreased in patients with AF recurrence. As for LA strain, it seems that LA strain increases in patients without AF recurrence, with less fibrosis and with more LA volumes decrease, but the differences were not significant.

Conclusions: Successful RFCA in patients with AF significantly decreases LA size and volumes and does not seem to adversely affect LA function.

No MeSH data available.


Related in: MedlinePlus

Forest plot of comparison of change in LAEF/LAAEF before ablation and after ablation.
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fig5-2054270414521185: Forest plot of comparison of change in LAEF/LAAEF before ablation and after ablation.

Mentions: Compared to pre-ablation values, there were no significant differences in the LAEF/LAAEF (WMD − 0.58%, 95% CI − 3.64% to 2.47%; Figure 5) after RFCA during follow-up. However, when analysed on the basis of AF recurrence, there were significant decreases in the LAEF/LAAEF in patients with AF recurrence, whereas there were no significant decreases in the LAEF/LAAEF in those with no AF recurrence (Figure 5).Figure 5.


Updating the evidence for the effect of radiofrequency catheter ablation on left atrial volume and function in patients with atrial fibrillation: a meta-analysis.

Zhuang Y, Yong YH, Chen ML - JRSM Open (2014)

Forest plot of comparison of change in LAEF/LAAEF before ablation and after ablation.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License 1 - License 2 - License 3
Show All Figures
getmorefigures.php?uid=PMC4012673&req=5

fig5-2054270414521185: Forest plot of comparison of change in LAEF/LAAEF before ablation and after ablation.
Mentions: Compared to pre-ablation values, there were no significant differences in the LAEF/LAAEF (WMD − 0.58%, 95% CI − 3.64% to 2.47%; Figure 5) after RFCA during follow-up. However, when analysed on the basis of AF recurrence, there were significant decreases in the LAEF/LAAEF in patients with AF recurrence, whereas there were no significant decreases in the LAEF/LAAEF in those with no AF recurrence (Figure 5).Figure 5.

Bottom Line: LA ejection fraction/LA active emptying fraction did not decrease in patients without AF recurrence, whereas they decreased in patients with AF recurrence.As for LA strain, it seems that LA strain increases in patients without AF recurrence, with less fibrosis and with more LA volumes decrease, but the differences were not significant.Successful RFCA in patients with AF significantly decreases LA size and volumes and does not seem to adversely affect LA function.

View Article: PubMed Central - PubMed

Affiliation: Intensive Care Unit, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029, China.

ABSTRACT

Objectives: To systematically review the effects of radiofrequency catheter ablation (RFCA) on left atrial (LA) size, volumes and function in patients with atrial fibrillation (AF).

Methods: We searched MEDLINE, EMBASE, ScienceDirect, Highwire, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews and the reference lists of retrieved reports in July 2012.

Setting: China.

Participants: Twenty-six studies (enrolling 1821 patients) were included in the final analysis.

Main outcome measures: Changes of LA size or volumes and/or function in patients with AF after RFCA.

Results: Compared to pre-ablation values, there were significant decreases in LA diameter and LA volumes at post-ablation follow-up. However, compared to pre-ablation values, there were no significant differences in LA ejection fraction/LA active emptying fraction and LA strain at post-ablation follow-up. Decreases in LA diameter and LA volumes remained significant in those without AF recurrence but not in those with AF recurrence. LA ejection fraction/LA active emptying fraction did not decrease in patients without AF recurrence, whereas they decreased in patients with AF recurrence. As for LA strain, it seems that LA strain increases in patients without AF recurrence, with less fibrosis and with more LA volumes decrease, but the differences were not significant.

Conclusions: Successful RFCA in patients with AF significantly decreases LA size and volumes and does not seem to adversely affect LA function.

No MeSH data available.


Related in: MedlinePlus