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The morphometry of soft tissue insertions on the tibial plateau: data acquisition and statistical shape analysis.

Zheng L, Harner CD, Zhang X - PLoS ONE (2014)

Bottom Line: The analyses resulted in statistical morphometric representations for Procrustes-superimposed cruciate ligament and meniscus insertions, and identified only a few moderate correlations (R2: 0.37-0.49).The study provided evidence challenging the isometric scaling based on a single dimension frequently employed in related morphometric studies, and data for evaluating cruciate ligament reconstruction strategies in terms of re-creating the native anatomy and minimizing the risk of iatrogenic injury.It paved the way for future development of computer-aided personalized orthopaedic surgery applications improving the quality of care and patient safety, and biomechanical models with a better population or average representation.

View Article: PubMed Central - PubMed

Affiliation: Departments of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

ABSTRACT
This study characterized the soft tissue insertion morphometrics on the tibial plateau and their inter-relationships as well as variabilities. The outlines of the cruciate ligament and meniscal root insertions along with the medial and lateral cartilage on 20 cadaveric tibias (10 left and 10 right knees) were digitized and co-registered with corresponding CT-based 3D bone models. Generalized Procrustes Analysis was employed in conjunction with Principal Components Analysis to first create a geometric consensus based on tibial cartilage and then determine the means and variations of insertion morphometrics including shape, size, location, and inter-relationship measures. Step-wise regression analysis was conducted in search of parsimonious models relating the morphometric measures to the tibial plateau width and depth, and basic anthropometric and gender factors. The analyses resulted in statistical morphometric representations for Procrustes-superimposed cruciate ligament and meniscus insertions, and identified only a few moderate correlations (R2: 0.37-0.49). The study provided evidence challenging the isometric scaling based on a single dimension frequently employed in related morphometric studies, and data for evaluating cruciate ligament reconstruction strategies in terms of re-creating the native anatomy and minimizing the risk of iatrogenic injury. It paved the way for future development of computer-aided personalized orthopaedic surgery applications improving the quality of care and patient safety, and biomechanical models with a better population or average representation.

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Related in: MedlinePlus

Statistical representations of tibial cartilage, cruciate ligament and meniscus insertion location and shape variability.The thick outlines are the mean or “most representative” shapes (the black thick outlines for tibial cartilage and the colored thick lines in the upper and lower subplots for six insertion sites); the color ellipses are 99% confidence ellipses for the insertion centroid locations resulting from PCA; the thin ellipses centered at the equidistant landmarks (20 on each outline) quantify the landmark position variability individually and the shape variability collectively.
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pone-0096515-g004: Statistical representations of tibial cartilage, cruciate ligament and meniscus insertion location and shape variability.The thick outlines are the mean or “most representative” shapes (the black thick outlines for tibial cartilage and the colored thick lines in the upper and lower subplots for six insertion sites); the color ellipses are 99% confidence ellipses for the insertion centroid locations resulting from PCA; the thin ellipses centered at the equidistant landmarks (20 on each outline) quantify the landmark position variability individually and the shape variability collectively.

Mentions: The Principal Components Analysis (PCA) of the insertion centroid location variability on the Procrustes-superimposed tibial plateaus resulted in 99% confidence ellipses quantifying the variability (Fig. 4). The major and minor axis lengths of the ellipses were 13.8 mm and 11.5 mm for ACL, 9.6 mm and 9.1 mm for PCL, 19.8 mm and 10.7 mm for AMMR, 11.8 mm and 6.1 mm for ALMR, 11.8 mm and 9.9 mm for PMMR, and 11.6 mm and 9.1 mm for PLMR. The PCA of equidistant landmarks on the contours of cartilage and insertion sites (on each) generated 99% confidence ellipses centered on the landmarks and thus quantified the variability of landmark locations individually and the variability of contour shape collectively (Fig. 4). Overall, the tibial cartilage contour shape varied more towards the anterior-posterior centerline. The shape variability of the insertion sites, especially of the meniscus roots, was much greater than that of the cartilage, as reflected by the relative sizes between the 99% confidence ellipses and the average shapes.


The morphometry of soft tissue insertions on the tibial plateau: data acquisition and statistical shape analysis.

Zheng L, Harner CD, Zhang X - PLoS ONE (2014)

Statistical representations of tibial cartilage, cruciate ligament and meniscus insertion location and shape variability.The thick outlines are the mean or “most representative” shapes (the black thick outlines for tibial cartilage and the colored thick lines in the upper and lower subplots for six insertion sites); the color ellipses are 99% confidence ellipses for the insertion centroid locations resulting from PCA; the thin ellipses centered at the equidistant landmarks (20 on each outline) quantify the landmark position variability individually and the shape variability collectively.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4008582&req=5

pone-0096515-g004: Statistical representations of tibial cartilage, cruciate ligament and meniscus insertion location and shape variability.The thick outlines are the mean or “most representative” shapes (the black thick outlines for tibial cartilage and the colored thick lines in the upper and lower subplots for six insertion sites); the color ellipses are 99% confidence ellipses for the insertion centroid locations resulting from PCA; the thin ellipses centered at the equidistant landmarks (20 on each outline) quantify the landmark position variability individually and the shape variability collectively.
Mentions: The Principal Components Analysis (PCA) of the insertion centroid location variability on the Procrustes-superimposed tibial plateaus resulted in 99% confidence ellipses quantifying the variability (Fig. 4). The major and minor axis lengths of the ellipses were 13.8 mm and 11.5 mm for ACL, 9.6 mm and 9.1 mm for PCL, 19.8 mm and 10.7 mm for AMMR, 11.8 mm and 6.1 mm for ALMR, 11.8 mm and 9.9 mm for PMMR, and 11.6 mm and 9.1 mm for PLMR. The PCA of equidistant landmarks on the contours of cartilage and insertion sites (on each) generated 99% confidence ellipses centered on the landmarks and thus quantified the variability of landmark locations individually and the variability of contour shape collectively (Fig. 4). Overall, the tibial cartilage contour shape varied more towards the anterior-posterior centerline. The shape variability of the insertion sites, especially of the meniscus roots, was much greater than that of the cartilage, as reflected by the relative sizes between the 99% confidence ellipses and the average shapes.

Bottom Line: The analyses resulted in statistical morphometric representations for Procrustes-superimposed cruciate ligament and meniscus insertions, and identified only a few moderate correlations (R2: 0.37-0.49).The study provided evidence challenging the isometric scaling based on a single dimension frequently employed in related morphometric studies, and data for evaluating cruciate ligament reconstruction strategies in terms of re-creating the native anatomy and minimizing the risk of iatrogenic injury.It paved the way for future development of computer-aided personalized orthopaedic surgery applications improving the quality of care and patient safety, and biomechanical models with a better population or average representation.

View Article: PubMed Central - PubMed

Affiliation: Departments of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

ABSTRACT
This study characterized the soft tissue insertion morphometrics on the tibial plateau and their inter-relationships as well as variabilities. The outlines of the cruciate ligament and meniscal root insertions along with the medial and lateral cartilage on 20 cadaveric tibias (10 left and 10 right knees) were digitized and co-registered with corresponding CT-based 3D bone models. Generalized Procrustes Analysis was employed in conjunction with Principal Components Analysis to first create a geometric consensus based on tibial cartilage and then determine the means and variations of insertion morphometrics including shape, size, location, and inter-relationship measures. Step-wise regression analysis was conducted in search of parsimonious models relating the morphometric measures to the tibial plateau width and depth, and basic anthropometric and gender factors. The analyses resulted in statistical morphometric representations for Procrustes-superimposed cruciate ligament and meniscus insertions, and identified only a few moderate correlations (R2: 0.37-0.49). The study provided evidence challenging the isometric scaling based on a single dimension frequently employed in related morphometric studies, and data for evaluating cruciate ligament reconstruction strategies in terms of re-creating the native anatomy and minimizing the risk of iatrogenic injury. It paved the way for future development of computer-aided personalized orthopaedic surgery applications improving the quality of care and patient safety, and biomechanical models with a better population or average representation.

Show MeSH
Related in: MedlinePlus