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Psoriasiform keratosis - case report.

Pires CA, Sousa BA, Nascimento Cdo S, Moutinho AT, Miranda MF, Carneiro FR - An Bras Dermatol (2014 Mar-Apr)

Bottom Line: The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities.Histopathological features closely resemble those of psoriasis.We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids.

View Article: PubMed Central - PubMed

Affiliation: Universidade do Estado do Pará, Belém, PA, Brazil.

ABSTRACT
Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.

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Single, keratotic plaque, located on the posterior surface of the left leg
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f01: Single, keratotic plaque, located on the posterior surface of the left leg

Mentions: This is a seventy year-old female patient, retired, born and raised in the city ofInhangapi (state of Pará). She complained of the appearance of a single and asymptomaticlesion on the posterior surface of the left leg, three months ago (Figure 1). She had used neomycin cream and betamethasonedipropionate ointment without any improvement. Histopathological examination revealedsections of skin showing epidermis with pronounced psoriasiform hyperplasia associatedwith hyperkeratosis, intra-corneal neutrophilic aggregates, vacuolated and pale aspectof more superficial keratinocytes and suprapapillary epidermal atrophy. In the upperdermal compartment, ectasic/congested vessels and perivascular and diffuse lymphocyticinflammatory infiltrate were observed. Absence of atypias was noted (Figures 2 and 3). Mycological examination and culture for fungi were negative. Excisionalbiopsy of the lesion was performed, without recurrence until present.


Psoriasiform keratosis - case report.

Pires CA, Sousa BA, Nascimento Cdo S, Moutinho AT, Miranda MF, Carneiro FR - An Bras Dermatol (2014 Mar-Apr)

Single, keratotic plaque, located on the posterior surface of the left leg
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4008064&req=5

f01: Single, keratotic plaque, located on the posterior surface of the left leg
Mentions: This is a seventy year-old female patient, retired, born and raised in the city ofInhangapi (state of Pará). She complained of the appearance of a single and asymptomaticlesion on the posterior surface of the left leg, three months ago (Figure 1). She had used neomycin cream and betamethasonedipropionate ointment without any improvement. Histopathological examination revealedsections of skin showing epidermis with pronounced psoriasiform hyperplasia associatedwith hyperkeratosis, intra-corneal neutrophilic aggregates, vacuolated and pale aspectof more superficial keratinocytes and suprapapillary epidermal atrophy. In the upperdermal compartment, ectasic/congested vessels and perivascular and diffuse lymphocyticinflammatory infiltrate were observed. Absence of atypias was noted (Figures 2 and 3). Mycological examination and culture for fungi were negative. Excisionalbiopsy of the lesion was performed, without recurrence until present.

Bottom Line: The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities.Histopathological features closely resemble those of psoriasis.We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids.

View Article: PubMed Central - PubMed

Affiliation: Universidade do Estado do Pará, Belém, PA, Brazil.

ABSTRACT
Psoriasiform Keratosis is a rare clinic entity. The etiopathogenesis remains unknown and the disease is characterized by a solitary, scaly or keratotic papule, or plaque mainly located on the extremities. Histopathological features closely resemble those of psoriasis. We report the case of a 70-year-old woman presenting a solitary and asymptomatic keratotic plaque, located on the back of the left leg, unresponsive to topical corticosteroids. We performed an excisional biopsy and histopathology was consistent with psoriasiform keratosis.

Show MeSH
Related in: MedlinePlus