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Potent health effects of pomegranate.

Zarfeshany A, Asgary S, Javanmard SH - Adv Biomed Res (2014)

Bottom Line: Pomegranate juice can reduce macrophage oxidative stress, free radicals, and lipid peroxidation.Moreover, pomegranate fruit extract prevents cell growth and induces apoptosis, which can lead to its anticarcinogenic effects.In this article, we highlight different studies on the therapeutic effects of pomegranate and their suggested mechanisms of actions.

View Article: PubMed Central - PubMed

Affiliation: Physiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan, Iran.

ABSTRACT
Accumulating data clearly claimed that Punica granatum L. (pomegranate) has several health benefits. Pomegranates can help prevent or treat various disease risk factors including high blood pressure, high cholesterol, oxidative stress, hyperglycemia, and inflammatory activities. It is demonstrated that certain components of pomegranate such as polyphenols have potential antioxidant, anti-inflammatory, and anticarcinogenic effects. The antioxidant potential of pomegranate juice is more than that of red wine and green tea, which is induced through ellagitannins and hydrosable tannins. Pomegranate juice can reduce macrophage oxidative stress, free radicals, and lipid peroxidation. Moreover, pomegranate fruit extract prevents cell growth and induces apoptosis, which can lead to its anticarcinogenic effects. In addition, promoter inhibition of some inflammatory markers and their production are blocked via ellagitannins. In this article, we highlight different studies on the therapeutic effects of pomegranate and their suggested mechanisms of actions.

No MeSH data available.


Related in: MedlinePlus

Chemical structure of punicic acid (9Z,11E,13Z-octadeca- 9,11,13-trienoic acid)
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Figure 1: Chemical structure of punicic acid (9Z,11E,13Z-octadeca- 9,11,13-trienoic acid)

Mentions: About 18% of dried and cleaned white seeds are oil. The oil is rich in punicic acid (65%), which is a triple conjugated 18-carbon fatty acid [Figure 1]. There are some phytoestrogen compounds in pomegranate seeds that have sex steroid hormones similar to those in humankind. The 17-alpha-estradiol is a mirror-image version of estrogen.[3]


Potent health effects of pomegranate.

Zarfeshany A, Asgary S, Javanmard SH - Adv Biomed Res (2014)

Chemical structure of punicic acid (9Z,11E,13Z-octadeca- 9,11,13-trienoic acid)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4007340&req=5

Figure 1: Chemical structure of punicic acid (9Z,11E,13Z-octadeca- 9,11,13-trienoic acid)
Mentions: About 18% of dried and cleaned white seeds are oil. The oil is rich in punicic acid (65%), which is a triple conjugated 18-carbon fatty acid [Figure 1]. There are some phytoestrogen compounds in pomegranate seeds that have sex steroid hormones similar to those in humankind. The 17-alpha-estradiol is a mirror-image version of estrogen.[3]

Bottom Line: Pomegranate juice can reduce macrophage oxidative stress, free radicals, and lipid peroxidation.Moreover, pomegranate fruit extract prevents cell growth and induces apoptosis, which can lead to its anticarcinogenic effects.In this article, we highlight different studies on the therapeutic effects of pomegranate and their suggested mechanisms of actions.

View Article: PubMed Central - PubMed

Affiliation: Physiology Research Center, Isfahan Cardiovascular Research Institute, Isfahan, Iran.

ABSTRACT
Accumulating data clearly claimed that Punica granatum L. (pomegranate) has several health benefits. Pomegranates can help prevent or treat various disease risk factors including high blood pressure, high cholesterol, oxidative stress, hyperglycemia, and inflammatory activities. It is demonstrated that certain components of pomegranate such as polyphenols have potential antioxidant, anti-inflammatory, and anticarcinogenic effects. The antioxidant potential of pomegranate juice is more than that of red wine and green tea, which is induced through ellagitannins and hydrosable tannins. Pomegranate juice can reduce macrophage oxidative stress, free radicals, and lipid peroxidation. Moreover, pomegranate fruit extract prevents cell growth and induces apoptosis, which can lead to its anticarcinogenic effects. In addition, promoter inhibition of some inflammatory markers and their production are blocked via ellagitannins. In this article, we highlight different studies on the therapeutic effects of pomegranate and their suggested mechanisms of actions.

No MeSH data available.


Related in: MedlinePlus