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The echocardiography in the cardiovascular laboratory: a guide to research with animals.

Abduch MC, Assad RS, Mathias W, Aiello VD - Arq. Bras. Cardiol. (2013)

Bottom Line: The feasibility and potential for the morphological and hemodynamic investigation of the heart has been increasing the use of the echocardiography in the research setting.Additionally, the development of new technologies, like the real time 3D echocardiography and speckle tracking, demands validation throughout experimental studies before being instituted in the clinical setting.This paper aims to provide information concerning the particularities of the echocardiographic examination in quadruped mammals, targeting the experimental research.

View Article: PubMed Central - PubMed

Affiliation: Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São PauloSP, Brasil.

ABSTRACT
The feasibility and potential for the morphological and hemodynamic investigation of the heart has been increasing the use of the echocardiography in the research setting. Additionally, the development of new technologies, like the real time 3D echocardiography and speckle tracking, demands validation throughout experimental studies before being instituted in the clinical setting. This paper aims to provide information concerning the particularities of the echocardiographic examination in quadruped mammals, targeting the experimental research.

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Customized stretcher for animals with kneel-shaped chest, in order to obtainthe parasternal echocardiographic views.
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Related In: Results  -  Collection

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getmorefigures.php?uid=PMC3987390&req=5

f01: Customized stretcher for animals with kneel-shaped chest, in order to obtainthe parasternal echocardiographic views.

Mentions: In order to acquire images of optimal quality, the animal should have its fur chestremoved, avoiding the presence of air between the transducer and the body surface,once it represents a barrier to the echo beam penetration. Besides that, sedation oranesthesia is crucial to the accuracy of the test; choosing the proper drug anddosage, according to the species, and the appraisal of possible alterations in thecardiovascular system should be scrutinized11. The positioning varies according to the animal model: fordogs and pigs, left lateral decubitus is indicated; rabbits and little rodents shouldbe kept in dorsal decubitus while ruminants need a customized stretcher due to theirextremely kneel-shaped chest. (Figure 1)


The echocardiography in the cardiovascular laboratory: a guide to research with animals.

Abduch MC, Assad RS, Mathias W, Aiello VD - Arq. Bras. Cardiol. (2013)

Customized stretcher for animals with kneel-shaped chest, in order to obtainthe parasternal echocardiographic views.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3987390&req=5

f01: Customized stretcher for animals with kneel-shaped chest, in order to obtainthe parasternal echocardiographic views.
Mentions: In order to acquire images of optimal quality, the animal should have its fur chestremoved, avoiding the presence of air between the transducer and the body surface,once it represents a barrier to the echo beam penetration. Besides that, sedation oranesthesia is crucial to the accuracy of the test; choosing the proper drug anddosage, according to the species, and the appraisal of possible alterations in thecardiovascular system should be scrutinized11. The positioning varies according to the animal model: fordogs and pigs, left lateral decubitus is indicated; rabbits and little rodents shouldbe kept in dorsal decubitus while ruminants need a customized stretcher due to theirextremely kneel-shaped chest. (Figure 1)

Bottom Line: The feasibility and potential for the morphological and hemodynamic investigation of the heart has been increasing the use of the echocardiography in the research setting.Additionally, the development of new technologies, like the real time 3D echocardiography and speckle tracking, demands validation throughout experimental studies before being instituted in the clinical setting.This paper aims to provide information concerning the particularities of the echocardiographic examination in quadruped mammals, targeting the experimental research.

View Article: PubMed Central - PubMed

Affiliation: Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, São PauloSP, Brasil.

ABSTRACT
The feasibility and potential for the morphological and hemodynamic investigation of the heart has been increasing the use of the echocardiography in the research setting. Additionally, the development of new technologies, like the real time 3D echocardiography and speckle tracking, demands validation throughout experimental studies before being instituted in the clinical setting. This paper aims to provide information concerning the particularities of the echocardiographic examination in quadruped mammals, targeting the experimental research.

Show MeSH