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Use of progestagens during early pregnancy.

Dante G, Vaccaro V, Facchinetti F - Facts Views Vis Obgyn (2013)

Bottom Line: The term "progestagens" covers a group of molecules including both the natural female sex hormones Progesterone and 17-hydroxy Progesterone as well as several synthetic forms, all displaying the ability to bind Progesterone receptors.Several studies have used Progesterone and related steroids in the attempt to prevent spontaneous miscarriage, and treat recurrent miscarriage.The present paper aims to provide a comprehensive review of the literature on progestagens effects during early pregnancy.

View Article: PubMed Central - PubMed

Affiliation: Mother-Infant Department, Unit of Obstetrics, University of Modena and Reggio Emilia, Italy.

ABSTRACT
The term "progestagens" covers a group of molecules including both the natural female sex hormones Progesterone and 17-hydroxy Progesterone as well as several synthetic forms, all displaying the ability to bind Progesterone receptors. Several studies have used Progesterone and related steroids in the attempt to prevent spontaneous miscarriage, and treat recurrent miscarriage. The present paper aims to provide a comprehensive review of the literature on progestagens effects during early pregnancy. We looked only at the results from randomized controlled trials. We found and analyzed 15 trials on the prevention of recurrent miscarriage and 2 trials on the treatment of miscarriage. The results demonstrated that there is no evidence to support the routine use of progestagens for the treatment of threatened miscarriage.

No MeSH data available.


Related in: MedlinePlus

Progesterone and Progestagens
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Related In: Results  -  Collection

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Figure 1: Progesterone and Progestagens

Mentions: Progesterone (Fig. 1) is a steroid hormone which plays a crucial role in each step of human pregnancy.


Use of progestagens during early pregnancy.

Dante G, Vaccaro V, Facchinetti F - Facts Views Vis Obgyn (2013)

Progesterone and Progestagens
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3987350&req=5

Figure 1: Progesterone and Progestagens
Mentions: Progesterone (Fig. 1) is a steroid hormone which plays a crucial role in each step of human pregnancy.

Bottom Line: The term "progestagens" covers a group of molecules including both the natural female sex hormones Progesterone and 17-hydroxy Progesterone as well as several synthetic forms, all displaying the ability to bind Progesterone receptors.Several studies have used Progesterone and related steroids in the attempt to prevent spontaneous miscarriage, and treat recurrent miscarriage.The present paper aims to provide a comprehensive review of the literature on progestagens effects during early pregnancy.

View Article: PubMed Central - PubMed

Affiliation: Mother-Infant Department, Unit of Obstetrics, University of Modena and Reggio Emilia, Italy.

ABSTRACT
The term "progestagens" covers a group of molecules including both the natural female sex hormones Progesterone and 17-hydroxy Progesterone as well as several synthetic forms, all displaying the ability to bind Progesterone receptors. Several studies have used Progesterone and related steroids in the attempt to prevent spontaneous miscarriage, and treat recurrent miscarriage. The present paper aims to provide a comprehensive review of the literature on progestagens effects during early pregnancy. We looked only at the results from randomized controlled trials. We found and analyzed 15 trials on the prevention of recurrent miscarriage and 2 trials on the treatment of miscarriage. The results demonstrated that there is no evidence to support the routine use of progestagens for the treatment of threatened miscarriage.

No MeSH data available.


Related in: MedlinePlus