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Effect of nitrogen atomic percentage on N+-bombarded MWCNTs in cytocompatibility and hemocompatibility.

Zhao M, Cao Y, Liu X, Deng J, Li D, Gu H - Nanoscale Res Lett (2014)

Bottom Line: The results showed that the presence of nitrogen in MWCNTs accelerated cell growth and proliferation of cell culture.The higher nitrogen content of N+-bombarded MWCNTs, the better cytocompatibility.These results proved that higher N atomic percentage led N+-bombarded MWCNTs to better hemocompatibility.

View Article: PubMed Central - HTML - PubMed

Affiliation: College of Physics and Materials Science, Tianjin Normal University, Tianjin 300387, China. dejunli@mail.tjnu.edu.cn.

ABSTRACT
N+-bombarded multi-walled carbon nanotubes (N+-bombarded MWCNTs), with different nitrogen atomic percentages, were achieved by different N ion beam currents using ion beam-assisted deposition (IBAD) on MWCNTs synthesized by chemical vapor deposition (CVD). Characterizations of N+-bombarded MWCNTs were evaluated by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), Raman spectroscopy, and contact angle. For comparison, the in vitro cytocompatibility of the N+-bombarded MWCNTs with different N atomic percentages was assessed by cellular adhesion investigation using human endothelial cells (EAHY926) and mouse fibroblast cells (L929), respectively. The results showed that the presence of nitrogen in MWCNTs accelerated cell growth and proliferation of cell culture. The higher nitrogen content of N+-bombarded MWCNTs, the better cytocompatibility. In addition, N+-bombarded MWCNTs with higher N atomic percentage displayed lower platelet adhesion rate. No hemolysis can be observed on the surfaces. These results proved that higher N atomic percentage led N+-bombarded MWCNTs to better hemocompatibility.

No MeSH data available.


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Raman spectra for N+-bombarded MWCNTs with three N atomic percentages.
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Figure 3: Raman spectra for N+-bombarded MWCNTs with three N atomic percentages.

Mentions: The Raman spectra of N+-bombarded MWCNTs at three N atomic percentages are shown in Figure 3. As can be observed, the samples show the typical D-mode (1,350 cm-1) and G-mode (1,590 cm-1) vibration bands and overtone of the D-mode (G′ 2,680 cm-1). A major effect of N introduction is increase clustering of the sp2 phase, which is indicated by the D peak [29]. In this study, we refer to I(D)/I(G) as the ratio of peak heights. In amorphous carbons, the development of a D peak indicates ordering [30]. So, it is noticeable that the ratio of I(D)/I(G) for N+-bombarded MWCNTs with N 8.67% atomic percentage is higher than those of the other samples, implying that nanotube destruction and creation of amorphous carbon impurities are introduced in the N ion bombardment.


Effect of nitrogen atomic percentage on N+-bombarded MWCNTs in cytocompatibility and hemocompatibility.

Zhao M, Cao Y, Liu X, Deng J, Li D, Gu H - Nanoscale Res Lett (2014)

Raman spectra for N+-bombarded MWCNTs with three N atomic percentages.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3987098&req=5

Figure 3: Raman spectra for N+-bombarded MWCNTs with three N atomic percentages.
Mentions: The Raman spectra of N+-bombarded MWCNTs at three N atomic percentages are shown in Figure 3. As can be observed, the samples show the typical D-mode (1,350 cm-1) and G-mode (1,590 cm-1) vibration bands and overtone of the D-mode (G′ 2,680 cm-1). A major effect of N introduction is increase clustering of the sp2 phase, which is indicated by the D peak [29]. In this study, we refer to I(D)/I(G) as the ratio of peak heights. In amorphous carbons, the development of a D peak indicates ordering [30]. So, it is noticeable that the ratio of I(D)/I(G) for N+-bombarded MWCNTs with N 8.67% atomic percentage is higher than those of the other samples, implying that nanotube destruction and creation of amorphous carbon impurities are introduced in the N ion bombardment.

Bottom Line: The results showed that the presence of nitrogen in MWCNTs accelerated cell growth and proliferation of cell culture.The higher nitrogen content of N+-bombarded MWCNTs, the better cytocompatibility.These results proved that higher N atomic percentage led N+-bombarded MWCNTs to better hemocompatibility.

View Article: PubMed Central - HTML - PubMed

Affiliation: College of Physics and Materials Science, Tianjin Normal University, Tianjin 300387, China. dejunli@mail.tjnu.edu.cn.

ABSTRACT
N+-bombarded multi-walled carbon nanotubes (N+-bombarded MWCNTs), with different nitrogen atomic percentages, were achieved by different N ion beam currents using ion beam-assisted deposition (IBAD) on MWCNTs synthesized by chemical vapor deposition (CVD). Characterizations of N+-bombarded MWCNTs were evaluated by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), Raman spectroscopy, and contact angle. For comparison, the in vitro cytocompatibility of the N+-bombarded MWCNTs with different N atomic percentages was assessed by cellular adhesion investigation using human endothelial cells (EAHY926) and mouse fibroblast cells (L929), respectively. The results showed that the presence of nitrogen in MWCNTs accelerated cell growth and proliferation of cell culture. The higher nitrogen content of N+-bombarded MWCNTs, the better cytocompatibility. In addition, N+-bombarded MWCNTs with higher N atomic percentage displayed lower platelet adhesion rate. No hemolysis can be observed on the surfaces. These results proved that higher N atomic percentage led N+-bombarded MWCNTs to better hemocompatibility.

No MeSH data available.


Related in: MedlinePlus