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Endoscopic imaging in Barrett's esophagus: current practice and future applications.

Gill RS, Singh R - Ann Gastroenterol (2012)

Bottom Line: Barrett's esophagus (BE) is a condition that develops as a consequence of chronic gastroesophageal reflux disease in which stratified squamous epithelium is replaced by metaplastic columnar epithelium which in turn predisposes to the development of adenocarcinoma of esophagus.In this review article, we discuss recent advances in the endoscopic imaging techniques for the detection of dysplasia and early carcinoma in BE.This will include some of the current available novel technologies as well as future applications specifically concentrating on high-resolution endoscopy, narrow band imaging, chromoendoscopy, confocal laser endomicroscopy and autofluorescence imaging.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology Advanced Trainee, Gosford Hospital, Division of Gastroenterology, NSW, Australia (Raghubinder Singh Gill).

ABSTRACT
Barrett's esophagus (BE) is a condition that develops as a consequence of chronic gastroesophageal reflux disease in which stratified squamous epithelium is replaced by metaplastic columnar epithelium which in turn predisposes to the development of adenocarcinoma of esophagus. In this review article, we discuss recent advances in the endoscopic imaging techniques for the detection of dysplasia and early carcinoma in BE. This will include some of the current available novel technologies as well as future applications specifically concentrating on high-resolution endoscopy, narrow band imaging, chromoendoscopy, confocal laser endomicroscopy and autofluorescence imaging.

No MeSH data available.


Related in: MedlinePlus

(A) Overview with high-resolution white light endoscopy: nodule in Barrett’s esophagus
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Figure 1: (A) Overview with high-resolution white light endoscopy: nodule in Barrett’s esophagus

Mentions: High-resolution endoscopes (HRE) are endoscopes equipped with high-density charged coupled device (CCD) chips enabling improved optics and images to be displayed at up to 850,000 pixels [39] (Fig. 1A). Magnification endoscopy enables the images to be magnified by up to 115 times by optical magnification [39]. These are major advancements in technology allowing for better visualization of the mucosa. Magnification endoscopy is best used in conjunction with chromoendoscopy [40-43]. A study by Sharma et al demonstrated that magnification chromoendoscopy helped to identify areas with IM and HGD [44]. The issue with this modality of imaging has been the high interbserver variability [45]. A study by Mayinger et al suggested that one reason for this is the difficulty in differentiating gastric cardiac mucosa from non-dysplastic Barrett’s mucosa [46].


Endoscopic imaging in Barrett's esophagus: current practice and future applications.

Gill RS, Singh R - Ann Gastroenterol (2012)

(A) Overview with high-resolution white light endoscopy: nodule in Barrett’s esophagus
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3959381&req=5

Figure 1: (A) Overview with high-resolution white light endoscopy: nodule in Barrett’s esophagus
Mentions: High-resolution endoscopes (HRE) are endoscopes equipped with high-density charged coupled device (CCD) chips enabling improved optics and images to be displayed at up to 850,000 pixels [39] (Fig. 1A). Magnification endoscopy enables the images to be magnified by up to 115 times by optical magnification [39]. These are major advancements in technology allowing for better visualization of the mucosa. Magnification endoscopy is best used in conjunction with chromoendoscopy [40-43]. A study by Sharma et al demonstrated that magnification chromoendoscopy helped to identify areas with IM and HGD [44]. The issue with this modality of imaging has been the high interbserver variability [45]. A study by Mayinger et al suggested that one reason for this is the difficulty in differentiating gastric cardiac mucosa from non-dysplastic Barrett’s mucosa [46].

Bottom Line: Barrett's esophagus (BE) is a condition that develops as a consequence of chronic gastroesophageal reflux disease in which stratified squamous epithelium is replaced by metaplastic columnar epithelium which in turn predisposes to the development of adenocarcinoma of esophagus.In this review article, we discuss recent advances in the endoscopic imaging techniques for the detection of dysplasia and early carcinoma in BE.This will include some of the current available novel technologies as well as future applications specifically concentrating on high-resolution endoscopy, narrow band imaging, chromoendoscopy, confocal laser endomicroscopy and autofluorescence imaging.

View Article: PubMed Central - PubMed

Affiliation: Gastroenterology Advanced Trainee, Gosford Hospital, Division of Gastroenterology, NSW, Australia (Raghubinder Singh Gill).

ABSTRACT
Barrett's esophagus (BE) is a condition that develops as a consequence of chronic gastroesophageal reflux disease in which stratified squamous epithelium is replaced by metaplastic columnar epithelium which in turn predisposes to the development of adenocarcinoma of esophagus. In this review article, we discuss recent advances in the endoscopic imaging techniques for the detection of dysplasia and early carcinoma in BE. This will include some of the current available novel technologies as well as future applications specifically concentrating on high-resolution endoscopy, narrow band imaging, chromoendoscopy, confocal laser endomicroscopy and autofluorescence imaging.

No MeSH data available.


Related in: MedlinePlus