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Small bowel enteroscopy in Crohn's disease.

Moreels TG - Ann Gastroenterol (2012)

Bottom Line: Endoscopic assessment of the small bowel is difficult because of its long and tortuous anatomy.It may be of help in the diagnostic assessment of intestinal disease extent and severity and complications, with an impact on the therapeutic management.Moreover, local treatment within the small bowel is also feasible with DAE.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology & Hepatology, Antwerp University Hospital, Belgium.

ABSTRACT
Endoscopic assessment of the small bowel is difficult because of its long and tortuous anatomy. However, recent developments have greatly improved the insertion depth and diagnostic yield, by means of device-assisted enteroscopy (DAE). Therefore, DAE may be of specific interest in the diagnostic and therapeutic approach of patients with inflammatory bowel disease. It may be of help in the diagnostic assessment of intestinal disease extent and severity and complications, with an impact on the therapeutic management. Moreover, local treatment within the small bowel is also feasible with DAE. This review aims to provide an overview of the currently available literature data on the use of enteroscopy in inflammatory bowel disease, and Crohn's disease in particular.

No MeSH data available.


Related in: MedlinePlus

A Gastrografin small bowel follow-through showing a retained wired videocapsule at an ileal Crohn’s disease stricture, B Single-balloon enteroscopy to retrieve the retained wireless videocapsule.
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Figure 2: A Gastrografin small bowel follow-through showing a retained wired videocapsule at an ileal Crohn’s disease stricture, B Single-balloon enteroscopy to retrieve the retained wireless videocapsule.

Mentions: Current literature: Recent studies also suggest that endoscopic small bowel assessment may have impact on future therapy, both medically and surgically. Local therapy appears feasible under the form of intestinal stricture balloon dilation or submucosal injection of anti-inflammatory drugs in strictures. Finally, enteroscopic retrieval of a retained WCE capsule has been described several times due to CD intestinal stricture (Fig. 2). Most published patient series on DAE focus on small bowel pathology in general and obscure GI bleeding in particular. Therefore, they also include some patients with IBD and (suspected) CD. Only a limited number of studies was specifically designed (both retrospectively and prospectively) to assess the role of DAE in CD. An overview is provided in Table 1.


Small bowel enteroscopy in Crohn's disease.

Moreels TG - Ann Gastroenterol (2012)

A Gastrografin small bowel follow-through showing a retained wired videocapsule at an ileal Crohn’s disease stricture, B Single-balloon enteroscopy to retrieve the retained wireless videocapsule.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3959356&req=5

Figure 2: A Gastrografin small bowel follow-through showing a retained wired videocapsule at an ileal Crohn’s disease stricture, B Single-balloon enteroscopy to retrieve the retained wireless videocapsule.
Mentions: Current literature: Recent studies also suggest that endoscopic small bowel assessment may have impact on future therapy, both medically and surgically. Local therapy appears feasible under the form of intestinal stricture balloon dilation or submucosal injection of anti-inflammatory drugs in strictures. Finally, enteroscopic retrieval of a retained WCE capsule has been described several times due to CD intestinal stricture (Fig. 2). Most published patient series on DAE focus on small bowel pathology in general and obscure GI bleeding in particular. Therefore, they also include some patients with IBD and (suspected) CD. Only a limited number of studies was specifically designed (both retrospectively and prospectively) to assess the role of DAE in CD. An overview is provided in Table 1.

Bottom Line: Endoscopic assessment of the small bowel is difficult because of its long and tortuous anatomy.It may be of help in the diagnostic assessment of intestinal disease extent and severity and complications, with an impact on the therapeutic management.Moreover, local treatment within the small bowel is also feasible with DAE.

View Article: PubMed Central - PubMed

Affiliation: Division of Gastroenterology & Hepatology, Antwerp University Hospital, Belgium.

ABSTRACT
Endoscopic assessment of the small bowel is difficult because of its long and tortuous anatomy. However, recent developments have greatly improved the insertion depth and diagnostic yield, by means of device-assisted enteroscopy (DAE). Therefore, DAE may be of specific interest in the diagnostic and therapeutic approach of patients with inflammatory bowel disease. It may be of help in the diagnostic assessment of intestinal disease extent and severity and complications, with an impact on the therapeutic management. Moreover, local treatment within the small bowel is also feasible with DAE. This review aims to provide an overview of the currently available literature data on the use of enteroscopy in inflammatory bowel disease, and Crohn's disease in particular.

No MeSH data available.


Related in: MedlinePlus