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Vascular calcification is not associated with increased ambulatory central aortic systolic pressure in prevalent dialysis patients.

Freercks RJ, Swanepool CR, Turest-Swartz KL, Carrara HR, El Moosa S, Lachman AS, Rayner BL - Cardiovasc J Afr (2014 Jan-Feb)

Bottom Line: HealthStats was able to convert standard BPro SOFT(®) data into ambulatory CASP.Inter-dialytic office blood pressure and CASP correlated excellently with ambulatory measurements (r = 0.9 for both).Inter-dialytic blood pressure and CASP correlated very well with ambulatory measurement.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1.Renal Unit, Groote Schuur Hospital, University of Cape Town, South Africa.

ABSTRACT

Introduction: Central aortic systolic pressure (CASP) strongly predicts cardiovascular outcomes. We undertook to measure ambulatory CASP in 74 prevalent dialysis patients using the BPro (HealthStats, Singapore) device. We also determined whether coronary or abdominal aortic calcification was associated with changes in CASP and whether interdialytic CASP predicted ambulatory measurement.

Methods: All patients underwent computed tomography for coronary calcium score, lateral abdominal radiography for aortic calcium score, echocardiography for left ventricular mass index and ambulatory blood pressure measurement using BPro calibrated to brachial blood pressure. HealthStats was able to convert standard BPro SOFT(®) data into ambulatory CASP.

Results: Ambulatory CASP was not different in those without and with coronary (137.6 vs 141.8 mmHg, respectively, p = 0.6) or aortic (136.6 vs 145.6 mmHg, respectively, p = 0.2) calcification. Furthermore, when expressed as a percentage of brachial systolic blood pressure to control for peripheral blood pressure, any difference in CASP was abolished: CASP: brachial systolic blood pressure ratio = 0.9 across all categories regardless of the presence of coronary or aortic calcification (p = 0.2 and 0.4, respectively). Supporting this finding, left ventricular mass index was also not different in those with or without vascular calcification (p = 0.7 and 0.8 for coronary and aortic calcification). Inter-dialytic office blood pressure and CASP correlated excellently with ambulatory measurements (r = 0.9 for both).

Conclusion: Vascular calcification was not associated with changes in ambulatory central aortic systolic pressure in this cohort of prevalent dialysis patients. Inter-dialytic blood pressure and CASP correlated very well with ambulatory measurement.

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Related in: MedlinePlus

Correlation between office and ambulatory systolic blood pressures.
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Figure 1: Correlation between office and ambulatory systolic blood pressures.

Mentions: Fig. 1. shows the correlation of office with ambulatory systolic blood pressure. Office systolic blood pressure and CASP correlated well with their ambulatory measurement (both r = 0.90).


Vascular calcification is not associated with increased ambulatory central aortic systolic pressure in prevalent dialysis patients.

Freercks RJ, Swanepool CR, Turest-Swartz KL, Carrara HR, El Moosa S, Lachman AS, Rayner BL - Cardiovasc J Afr (2014 Jan-Feb)

Correlation between office and ambulatory systolic blood pressures.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3959179&req=5

Figure 1: Correlation between office and ambulatory systolic blood pressures.
Mentions: Fig. 1. shows the correlation of office with ambulatory systolic blood pressure. Office systolic blood pressure and CASP correlated well with their ambulatory measurement (both r = 0.90).

Bottom Line: HealthStats was able to convert standard BPro SOFT(®) data into ambulatory CASP.Inter-dialytic office blood pressure and CASP correlated excellently with ambulatory measurements (r = 0.9 for both).Inter-dialytic blood pressure and CASP correlated very well with ambulatory measurement.

View Article: PubMed Central - HTML - PubMed

Affiliation: 1.Renal Unit, Groote Schuur Hospital, University of Cape Town, South Africa.

ABSTRACT

Introduction: Central aortic systolic pressure (CASP) strongly predicts cardiovascular outcomes. We undertook to measure ambulatory CASP in 74 prevalent dialysis patients using the BPro (HealthStats, Singapore) device. We also determined whether coronary or abdominal aortic calcification was associated with changes in CASP and whether interdialytic CASP predicted ambulatory measurement.

Methods: All patients underwent computed tomography for coronary calcium score, lateral abdominal radiography for aortic calcium score, echocardiography for left ventricular mass index and ambulatory blood pressure measurement using BPro calibrated to brachial blood pressure. HealthStats was able to convert standard BPro SOFT(®) data into ambulatory CASP.

Results: Ambulatory CASP was not different in those without and with coronary (137.6 vs 141.8 mmHg, respectively, p = 0.6) or aortic (136.6 vs 145.6 mmHg, respectively, p = 0.2) calcification. Furthermore, when expressed as a percentage of brachial systolic blood pressure to control for peripheral blood pressure, any difference in CASP was abolished: CASP: brachial systolic blood pressure ratio = 0.9 across all categories regardless of the presence of coronary or aortic calcification (p = 0.2 and 0.4, respectively). Supporting this finding, left ventricular mass index was also not different in those with or without vascular calcification (p = 0.7 and 0.8 for coronary and aortic calcification). Inter-dialytic office blood pressure and CASP correlated excellently with ambulatory measurements (r = 0.9 for both).

Conclusion: Vascular calcification was not associated with changes in ambulatory central aortic systolic pressure in this cohort of prevalent dialysis patients. Inter-dialytic blood pressure and CASP correlated very well with ambulatory measurement.

Show MeSH
Related in: MedlinePlus