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Testis scintigraphy in a patient with acute lymphoblastic leukemia.

Eren MS, Koç M, Oren H, Ozkal S, Durak H - Mol Imaging Radionucl Ther (2014)

Bottom Line: Acute lymphoblastic leukemia (ALL) is a pediatric malignancy associated with remissions and relapses.There is only one interesting image on leukemic infiltration with scrotal scintigraphy in the literature.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Dokuz Eylül University School of Medicine, Department of Nuclear Medicine, İzmir, Turkey.

ABSTRACT

Unlabelled: Acute lymphoblastic leukemia (ALL) is a pediatric malignancy associated with remissions and relapses. Common relapsing sitesare meninges, testis and ovary. Testicular scintigraphy is a highly specific modality used mainly in the differential diagnosis of testicular torsion and epidydimitis/epidydimo-orchitis. There is only one interesting image on leukemic infiltration with scrotal scintigraphy in the literature. The aim of this case presentation is to report that although the scintigraphic appearance of testicular torsion was observed in a patient with the diagnosis of ALL, testicular ALL infiltration was revealed in pathologic examination.

Conflict of interest: None declared.

No MeSH data available.


Related in: MedlinePlus

The anterior pinhole view of testis scintigraphy showing hypoactive left testicular area surrounded by an hyperactive halo.
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f2: The anterior pinhole view of testis scintigraphy showing hypoactive left testicular area surrounded by an hyperactive halo.

Mentions: Penis was elevated upwards and fixed to pelvic bone with adhesive band. Imaging was performed with Low Energy General Purpose (LEGP) collimator. Following intravenous administration of 10 mCi Tc-99m pertechnetate, dynamic perfusion images were obtained in order to examine blood supply of testis, followed by pinhole and static images. In dynamic images, perfusion in the area suggestive of left testis was decreased. In static images, the left testicular area was hypoactive and a hyperactive halo surrounding this area was noted (Figure 1). Those findings were observed better in pinhole images (Figure 2). In the light of those findings, patient was considered to have subacute left testicular torsion. Patient underwent left orchidectomy. In the histopathological examination, lymphoblastic lymphoma infiltration was observed in testicular tissue. Diffuse lymphoblastic cells in the testicular tissue had replaced the entire testicular structure (Figure 3). Immunohistochemical staining revealed Terminal Deoxynucleotidyl Transferase (TDT) (Figure 4) and CD-10 (Figure 5) positivity in lymphoblastic cells.


Testis scintigraphy in a patient with acute lymphoblastic leukemia.

Eren MS, Koç M, Oren H, Ozkal S, Durak H - Mol Imaging Radionucl Ther (2014)

The anterior pinhole view of testis scintigraphy showing hypoactive left testicular area surrounded by an hyperactive halo.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3957971&req=5

f2: The anterior pinhole view of testis scintigraphy showing hypoactive left testicular area surrounded by an hyperactive halo.
Mentions: Penis was elevated upwards and fixed to pelvic bone with adhesive band. Imaging was performed with Low Energy General Purpose (LEGP) collimator. Following intravenous administration of 10 mCi Tc-99m pertechnetate, dynamic perfusion images were obtained in order to examine blood supply of testis, followed by pinhole and static images. In dynamic images, perfusion in the area suggestive of left testis was decreased. In static images, the left testicular area was hypoactive and a hyperactive halo surrounding this area was noted (Figure 1). Those findings were observed better in pinhole images (Figure 2). In the light of those findings, patient was considered to have subacute left testicular torsion. Patient underwent left orchidectomy. In the histopathological examination, lymphoblastic lymphoma infiltration was observed in testicular tissue. Diffuse lymphoblastic cells in the testicular tissue had replaced the entire testicular structure (Figure 3). Immunohistochemical staining revealed Terminal Deoxynucleotidyl Transferase (TDT) (Figure 4) and CD-10 (Figure 5) positivity in lymphoblastic cells.

Bottom Line: Acute lymphoblastic leukemia (ALL) is a pediatric malignancy associated with remissions and relapses.There is only one interesting image on leukemic infiltration with scrotal scintigraphy in the literature.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Dokuz Eylül University School of Medicine, Department of Nuclear Medicine, İzmir, Turkey.

ABSTRACT

Unlabelled: Acute lymphoblastic leukemia (ALL) is a pediatric malignancy associated with remissions and relapses. Common relapsing sitesare meninges, testis and ovary. Testicular scintigraphy is a highly specific modality used mainly in the differential diagnosis of testicular torsion and epidydimitis/epidydimo-orchitis. There is only one interesting image on leukemic infiltration with scrotal scintigraphy in the literature. The aim of this case presentation is to report that although the scintigraphic appearance of testicular torsion was observed in a patient with the diagnosis of ALL, testicular ALL infiltration was revealed in pathologic examination.

Conflict of interest: None declared.

No MeSH data available.


Related in: MedlinePlus