Limits...
The relationship between the 24 h blood pressure variability and carotid intima-media thickness: a compared study.

Xiong H, Wu D, Tian X, Lin WH, Li C, Zhang H, Cai Y, Zhang YT - Comput Math Methods Med (2014)

Bottom Line: The results show that both the daytime, and 24 h systolic BPV evaluated by three indices are positively associated with IMT.Among them, daytime systolic BPV evaluated with ARV is the best variable to represent the increasing of carotid IMT.In addition, after adjusting by age, sex, smoking, hypertension, and mean BP and PP values, 24 h diastolic BPV evaluated with SD also presents the favorable performance.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, The Second Peoples' Hospital of Shenzhen, Shenzhen 518029, China.

ABSTRACT
Large blood pressure variability (BPV) will not only harm the target organ but also increase the possibility of the cardiovascular events. Since the damage of vascular system always leads to the alteration of the carotid wall, the structure and function of the carotid artery have been extensively examined in previous studies. In this work we conduct a study (60 subjects, aged 33-79) to evaluate the relationship between BPV and carotid intima-media thickness (IMT) in Shenzhen, which is one large city in the southern area of China. In our study, the blood pressure (BP) was collected using the 24 h ambulatory BP monitoring, and the BPV was evaluated using standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) during 24 h, daytime and nighttime. All the IMT measurements are collected by ultrasound. The results show that both the daytime, and 24 h systolic BPV evaluated by three indices are positively associated with IMT. Among them, daytime systolic BPV evaluated with ARV is the best variable to represent the increasing of carotid IMT. In addition, after adjusting by age, sex, smoking, hypertension, and mean BP and PP values, 24 h diastolic BPV evaluated with SD also presents the favorable performance.

Show MeSH

Related in: MedlinePlus

Linear correlation between common carotid artery intima-media thickness (IMT) and 24 h systolic blood pressure variability (SBPV) (SD), 24 h diastolic blood pressure variability (DBPV) (CV) and daytime systolic blood pressure variability (SBPV) (ARV).
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3934393&req=5

fig2: Linear correlation between common carotid artery intima-media thickness (IMT) and 24 h systolic blood pressure variability (SBPV) (SD), 24 h diastolic blood pressure variability (DBPV) (CV) and daytime systolic blood pressure variability (SBPV) (ARV).

Mentions: Before evaluating the effects of different indices of BPV on the carotid IMT, a simple linear regression analysis was performed for each BPV index. 24 h SBPV (SD), 24 h DBPV (CV), and daytime SBPV (ARV) presented the highly linear correlations with carotid IMT, which were shown in Figure 2.


The relationship between the 24 h blood pressure variability and carotid intima-media thickness: a compared study.

Xiong H, Wu D, Tian X, Lin WH, Li C, Zhang H, Cai Y, Zhang YT - Comput Math Methods Med (2014)

Linear correlation between common carotid artery intima-media thickness (IMT) and 24 h systolic blood pressure variability (SBPV) (SD), 24 h diastolic blood pressure variability (DBPV) (CV) and daytime systolic blood pressure variability (SBPV) (ARV).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3934393&req=5

fig2: Linear correlation between common carotid artery intima-media thickness (IMT) and 24 h systolic blood pressure variability (SBPV) (SD), 24 h diastolic blood pressure variability (DBPV) (CV) and daytime systolic blood pressure variability (SBPV) (ARV).
Mentions: Before evaluating the effects of different indices of BPV on the carotid IMT, a simple linear regression analysis was performed for each BPV index. 24 h SBPV (SD), 24 h DBPV (CV), and daytime SBPV (ARV) presented the highly linear correlations with carotid IMT, which were shown in Figure 2.

Bottom Line: The results show that both the daytime, and 24 h systolic BPV evaluated by three indices are positively associated with IMT.Among them, daytime systolic BPV evaluated with ARV is the best variable to represent the increasing of carotid IMT.In addition, after adjusting by age, sex, smoking, hypertension, and mean BP and PP values, 24 h diastolic BPV evaluated with SD also presents the favorable performance.

View Article: PubMed Central - PubMed

Affiliation: Department of Ultrasound, The Second Peoples' Hospital of Shenzhen, Shenzhen 518029, China.

ABSTRACT
Large blood pressure variability (BPV) will not only harm the target organ but also increase the possibility of the cardiovascular events. Since the damage of vascular system always leads to the alteration of the carotid wall, the structure and function of the carotid artery have been extensively examined in previous studies. In this work we conduct a study (60 subjects, aged 33-79) to evaluate the relationship between BPV and carotid intima-media thickness (IMT) in Shenzhen, which is one large city in the southern area of China. In our study, the blood pressure (BP) was collected using the 24 h ambulatory BP monitoring, and the BPV was evaluated using standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) during 24 h, daytime and nighttime. All the IMT measurements are collected by ultrasound. The results show that both the daytime, and 24 h systolic BPV evaluated by three indices are positively associated with IMT. Among them, daytime systolic BPV evaluated with ARV is the best variable to represent the increasing of carotid IMT. In addition, after adjusting by age, sex, smoking, hypertension, and mean BP and PP values, 24 h diastolic BPV evaluated with SD also presents the favorable performance.

Show MeSH
Related in: MedlinePlus