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Daily rest-activity patterns in the bipolar phenotype: A controlled actigraphy study.

Rock P, Goodwin G, Harmer C, Wulff K - Chronobiol. Int. (2013)

Bottom Line: This study assessed daily rest-activity patterns in euthymic, medication-naïve bipolar phenotype individuals.Participants wore an Actiwatch-L for 2 weeks to assess their sleep behaviour and circadian rest-activity rhythmicity.Higher activity levels during sleep affecting circadian amplitude in young adults with the bipolar phenotype may be associated with vulnerability for developing mood disorder.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, University of Oxford , Oxford , UK .

ABSTRACT
This study assessed daily rest-activity patterns in euthymic, medication-naïve bipolar phenotype individuals. The Mood Disorder Questionnaire was used to identify 19 bipolar phenotype individuals and 21 controls. Participants wore an Actiwatch-L for 2 weeks to assess their sleep behaviour and circadian rest-activity rhythmicity. Bipolar phenotype individuals had increased movement during sleep, as assessed by the fragmentation index, greater activity levels during their least active 5 h (2 am-7 am), and lower circadian relative amplitude compared to controls. Higher activity levels during sleep affecting circadian amplitude in young adults with the bipolar phenotype may be associated with vulnerability for developing mood disorder.

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Related in: MedlinePlus

Representative examples of rest-activity patterns derived from 2 weeks’ wrist activity monitoring in control (upper panel) and bipolar phenotype (lower panel) female individuals. Actigraphic data are 48-h double plotted with successive days on vertical axis. Midline indicates midnight between day 1 and day 2. Edited data are highlighted with “___”.
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f1: Representative examples of rest-activity patterns derived from 2 weeks’ wrist activity monitoring in control (upper panel) and bipolar phenotype (lower panel) female individuals. Actigraphic data are 48-h double plotted with successive days on vertical axis. Midline indicates midnight between day 1 and day 2. Edited data are highlighted with “___”.

Mentions: The bipolar phenotype participants had 9–15 days of actigraphy data and the control participants had 9–16 days of actigraphy data. Representative examples of rest-activity patterns in bipolar phenotype and control individuals are shown in Figure 1.Figure 1.


Daily rest-activity patterns in the bipolar phenotype: A controlled actigraphy study.

Rock P, Goodwin G, Harmer C, Wulff K - Chronobiol. Int. (2013)

Representative examples of rest-activity patterns derived from 2 weeks’ wrist activity monitoring in control (upper panel) and bipolar phenotype (lower panel) female individuals. Actigraphic data are 48-h double plotted with successive days on vertical axis. Midline indicates midnight between day 1 and day 2. Edited data are highlighted with “___”.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3934377&req=5

f1: Representative examples of rest-activity patterns derived from 2 weeks’ wrist activity monitoring in control (upper panel) and bipolar phenotype (lower panel) female individuals. Actigraphic data are 48-h double plotted with successive days on vertical axis. Midline indicates midnight between day 1 and day 2. Edited data are highlighted with “___”.
Mentions: The bipolar phenotype participants had 9–15 days of actigraphy data and the control participants had 9–16 days of actigraphy data. Representative examples of rest-activity patterns in bipolar phenotype and control individuals are shown in Figure 1.Figure 1.

Bottom Line: This study assessed daily rest-activity patterns in euthymic, medication-naïve bipolar phenotype individuals.Participants wore an Actiwatch-L for 2 weeks to assess their sleep behaviour and circadian rest-activity rhythmicity.Higher activity levels during sleep affecting circadian amplitude in young adults with the bipolar phenotype may be associated with vulnerability for developing mood disorder.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychiatry, University of Oxford , Oxford , UK .

ABSTRACT
This study assessed daily rest-activity patterns in euthymic, medication-naïve bipolar phenotype individuals. The Mood Disorder Questionnaire was used to identify 19 bipolar phenotype individuals and 21 controls. Participants wore an Actiwatch-L for 2 weeks to assess their sleep behaviour and circadian rest-activity rhythmicity. Bipolar phenotype individuals had increased movement during sleep, as assessed by the fragmentation index, greater activity levels during their least active 5 h (2 am-7 am), and lower circadian relative amplitude compared to controls. Higher activity levels during sleep affecting circadian amplitude in young adults with the bipolar phenotype may be associated with vulnerability for developing mood disorder.

Show MeSH
Related in: MedlinePlus