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Report of two cases of fluorodeoxyglucose positron emission tomography/computed tomography appearance of hibernoma: A rare benign tumor.

Agrawal A, Kembhavi S, Purandare N, Shah S, Rangarajan V - Indian J Nucl Med (2014)

Bottom Line: False-positive findings are commonly seen in positron emission tomography computed tomography imaging.One of the most common false positive finding is uptake of fluorodeoxyglucose in brown adipose tissue.Herein, we report two cases with incidentally detected hibernomas-a brown fat containing tumor with metabolic activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.

ABSTRACT
False-positive findings are commonly seen in positron emission tomography computed tomography imaging. One of the most common false positive finding is uptake of fluorodeoxyglucose in brown adipose tissue. Herein, we report two cases with incidentally detected hibernomas-a brown fat containing tumor with metabolic activity.

No MeSH data available.


Related in: MedlinePlus

Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan, maximum intensity projection image showing metabolically active right breast mass (block arrow), right axillary nodes (arrow) and in the left lower thorax-the hypermetabolic hibernoma (notched arrow). Unenhanced axial CT image (a) shows a low attenuating, well-defined mass lesion in the left postero-lateral chest wall (arrow). The contrast enhanced CT (b) shows mild homogenous enhancement. FDG PET (c) and fused images (d) show an intensely FDG avid mass
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Figure 1: Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan, maximum intensity projection image showing metabolically active right breast mass (block arrow), right axillary nodes (arrow) and in the left lower thorax-the hypermetabolic hibernoma (notched arrow). Unenhanced axial CT image (a) shows a low attenuating, well-defined mass lesion in the left postero-lateral chest wall (arrow). The contrast enhanced CT (b) shows mild homogenous enhancement. FDG PET (c) and fused images (d) show an intensely FDG avid mass

Mentions: This was a case report of a 45-year-old lady, a case of the right breast carcinoma with ipsilateral axillary nodal and liver metastases; underwent a PET/CT scan post-six cycles of chemotherapy. The scan revealed hypermetabolic right breast mass, metastatic right supraclavicular and axillary lymphadenopathy and liver metastases [Figure 1, maximum intensity projection (MIP)]. Apart from this a hypermetabolic (maxSUV 20.9), low-attenuating, well-defined mass lesion was noted in the left postero-lateral chest wall [Figure 1a-d]. This mass was relatively hyperdense to the surrounding subcutaneous fat. This mass had remained unchanged since the previous CT scan (pre-treatment), which was done 4 months ago. The imaging findings led to the diagnosis of a benign fat containing tumor – hibernoma. On a clinical follow-up, a year later after the PET/CT study this painless, soft swelling in the left postero-lateral chest wall remained unchanged confirming the benignity of this rare tumor.


Report of two cases of fluorodeoxyglucose positron emission tomography/computed tomography appearance of hibernoma: A rare benign tumor.

Agrawal A, Kembhavi S, Purandare N, Shah S, Rangarajan V - Indian J Nucl Med (2014)

Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan, maximum intensity projection image showing metabolically active right breast mass (block arrow), right axillary nodes (arrow) and in the left lower thorax-the hypermetabolic hibernoma (notched arrow). Unenhanced axial CT image (a) shows a low attenuating, well-defined mass lesion in the left postero-lateral chest wall (arrow). The contrast enhanced CT (b) shows mild homogenous enhancement. FDG PET (c) and fused images (d) show an intensely FDG avid mass
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3928751&req=5

Figure 1: Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan, maximum intensity projection image showing metabolically active right breast mass (block arrow), right axillary nodes (arrow) and in the left lower thorax-the hypermetabolic hibernoma (notched arrow). Unenhanced axial CT image (a) shows a low attenuating, well-defined mass lesion in the left postero-lateral chest wall (arrow). The contrast enhanced CT (b) shows mild homogenous enhancement. FDG PET (c) and fused images (d) show an intensely FDG avid mass
Mentions: This was a case report of a 45-year-old lady, a case of the right breast carcinoma with ipsilateral axillary nodal and liver metastases; underwent a PET/CT scan post-six cycles of chemotherapy. The scan revealed hypermetabolic right breast mass, metastatic right supraclavicular and axillary lymphadenopathy and liver metastases [Figure 1, maximum intensity projection (MIP)]. Apart from this a hypermetabolic (maxSUV 20.9), low-attenuating, well-defined mass lesion was noted in the left postero-lateral chest wall [Figure 1a-d]. This mass was relatively hyperdense to the surrounding subcutaneous fat. This mass had remained unchanged since the previous CT scan (pre-treatment), which was done 4 months ago. The imaging findings led to the diagnosis of a benign fat containing tumor – hibernoma. On a clinical follow-up, a year later after the PET/CT study this painless, soft swelling in the left postero-lateral chest wall remained unchanged confirming the benignity of this rare tumor.

Bottom Line: False-positive findings are commonly seen in positron emission tomography computed tomography imaging.One of the most common false positive finding is uptake of fluorodeoxyglucose in brown adipose tissue.Herein, we report two cases with incidentally detected hibernomas-a brown fat containing tumor with metabolic activity.

View Article: PubMed Central - PubMed

Affiliation: Department of Nuclear Medicine and Molecular Imaging, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.

ABSTRACT
False-positive findings are commonly seen in positron emission tomography computed tomography imaging. One of the most common false positive finding is uptake of fluorodeoxyglucose in brown adipose tissue. Herein, we report two cases with incidentally detected hibernomas-a brown fat containing tumor with metabolic activity.

No MeSH data available.


Related in: MedlinePlus