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Cataract subtype risk factors identified from the Korea National Health and Nutrition Examination survey 2008-2010.

Rim TH, Kim MH, Kim WC, Kim TI, Kim EK - BMC Ophthalmol (2014)

Bottom Line: Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts.Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts.Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. eungkkim@yuhs.ac.

ABSTRACT

Background: To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea.

Methods: A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducted detailed ophthalmologic examinations on these participants based on the Lens Opacity Classification System III. Risk factors for developing any type of cataract, and its subtypes (nuclear, cortical, posterior subcapsular and mixed), were identified from univariate and multivariate logistic regression analysis.

Results: The prevalence of cataracts was 40.1% (95% CI, 37.8 - 42.3%) in participants over 40 years old. Older age, lower monthly household income, lower education, hypercholesterolemia, hypertension, and diabetes mellitus (DM) were independent risk factors for development of any cataract. Older age, lower monthly household income, lower education, hypercholesterolemia, and DM were independent risk factors for development of pure cortical cataracts. Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts. Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts. Older age, lower monthly household income, lower education, and DM were independent risk factors for development of mixed cataracts.

Conclusion: Although socioeconomic disparities are related to cataract development, this study identified several "modifiable" risk factors that may help to lower the incidence of cataracts and associated vision loss. Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

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Flow chart shows how to classify the each subtype of cataract in detail.
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Figure 4: Flow chart shows how to classify the each subtype of cataract in detail.

Mentions: To identify risk factors for any type of cataract, we first verified cataract occurrence in a person with the presence of a nuclear, cortical, anterior subcapsular, or posterior subcapsular cataract in at least one eye. For statistical purposes, we also included pseudophakic and aphakic eyes as operated cataracts for calculating prevalence. To analyze and evaluate risk factors for each type of cataract, we defined the cataract subtypes as follows. Participants with no type of cataract in either phakic eye were defined as having no cataract. Individuals who had a cortical cataract in at least one eye were defined as having a pure cortical cataract. Individuals with either a nuclear cataract or a PSCO were similarly defined. Individuals with a mixed type cataract, which included an anterior subcapsular type in at least one eye, were defined as having a mixed type cataract (Figure 2). Figure 4 shows how the cataract subtypes were categorized in detail using a flow chart.


Cataract subtype risk factors identified from the Korea National Health and Nutrition Examination survey 2008-2010.

Rim TH, Kim MH, Kim WC, Kim TI, Kim EK - BMC Ophthalmol (2014)

Flow chart shows how to classify the each subtype of cataract in detail.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3928645&req=5

Figure 4: Flow chart shows how to classify the each subtype of cataract in detail.
Mentions: To identify risk factors for any type of cataract, we first verified cataract occurrence in a person with the presence of a nuclear, cortical, anterior subcapsular, or posterior subcapsular cataract in at least one eye. For statistical purposes, we also included pseudophakic and aphakic eyes as operated cataracts for calculating prevalence. To analyze and evaluate risk factors for each type of cataract, we defined the cataract subtypes as follows. Participants with no type of cataract in either phakic eye were defined as having no cataract. Individuals who had a cortical cataract in at least one eye were defined as having a pure cortical cataract. Individuals with either a nuclear cataract or a PSCO were similarly defined. Individuals with a mixed type cataract, which included an anterior subcapsular type in at least one eye, were defined as having a mixed type cataract (Figure 2). Figure 4 shows how the cataract subtypes were categorized in detail using a flow chart.

Bottom Line: Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts.Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts.Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. eungkkim@yuhs.ac.

ABSTRACT

Background: To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea.

Methods: A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducted detailed ophthalmologic examinations on these participants based on the Lens Opacity Classification System III. Risk factors for developing any type of cataract, and its subtypes (nuclear, cortical, posterior subcapsular and mixed), were identified from univariate and multivariate logistic regression analysis.

Results: The prevalence of cataracts was 40.1% (95% CI, 37.8 - 42.3%) in participants over 40 years old. Older age, lower monthly household income, lower education, hypercholesterolemia, hypertension, and diabetes mellitus (DM) were independent risk factors for development of any cataract. Older age, lower monthly household income, lower education, hypercholesterolemia, and DM were independent risk factors for development of pure cortical cataracts. Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts. Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts. Older age, lower monthly household income, lower education, and DM were independent risk factors for development of mixed cataracts.

Conclusion: Although socioeconomic disparities are related to cataract development, this study identified several "modifiable" risk factors that may help to lower the incidence of cataracts and associated vision loss. Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

Show MeSH
Related in: MedlinePlus