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Cataract subtype risk factors identified from the Korea National Health and Nutrition Examination survey 2008-2010.

Rim TH, Kim MH, Kim WC, Kim TI, Kim EK - BMC Ophthalmol (2014)

Bottom Line: Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts.Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts.Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. eungkkim@yuhs.ac.

ABSTRACT

Background: To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea.

Methods: A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducted detailed ophthalmologic examinations on these participants based on the Lens Opacity Classification System III. Risk factors for developing any type of cataract, and its subtypes (nuclear, cortical, posterior subcapsular and mixed), were identified from univariate and multivariate logistic regression analysis.

Results: The prevalence of cataracts was 40.1% (95% CI, 37.8 - 42.3%) in participants over 40 years old. Older age, lower monthly household income, lower education, hypercholesterolemia, hypertension, and diabetes mellitus (DM) were independent risk factors for development of any cataract. Older age, lower monthly household income, lower education, hypercholesterolemia, and DM were independent risk factors for development of pure cortical cataracts. Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts. Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts. Older age, lower monthly household income, lower education, and DM were independent risk factors for development of mixed cataracts.

Conclusion: Although socioeconomic disparities are related to cataract development, this study identified several "modifiable" risk factors that may help to lower the incidence of cataracts and associated vision loss. Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

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Related in: MedlinePlus

Standard pictures for each subtype. A. Nuclear type, B. Cortical type, C. Anterior capsular type, D. Posterior capsular type.
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Figure 3: Standard pictures for each subtype. A. Nuclear type, B. Cortical type, C. Anterior capsular type, D. Posterior capsular type.

Mentions: Designated ophthalmologists performed a structured slit-lamp examination (Haag-Streit model BQ-900, Haag-Streit AG, Koeniz, Switzerland) to determine disease occurrence in the anterior segment of the eye (e.g., pterygium and cataract). Examinees were seated in the examination chair, resting their chin and forehead on the support. An illuminator was positioned behind the examinees’ ears; the angle between the illuminator and the microscope was 30 ~ 45 degrees with a 10× magnification.Without iridodilator usage, the characteristics of lens were assessed using slit lamp with proper brightness, height, and width. The overall characteristics of the lens were examined with a wider slit lamp, and the type and severity of the cataract was determined according to transparency, turbidity, pigments, vacuoles and nuclei. Each layer of the lens was examined with the focused slit lamp from the anterior capsule to the posterior capsule. Aphakia and pseudophakia were recorded separately, and excluded from the subtype analysis. The type of cataract was categorized according to Lens Opacity Classification System III (LOCS III) grading in both eyes, as nuclear, cortical, PSCO, or mixed (including anterior subcapsular). Standard pictures for each subtype were provided for each examiner (Figure 3). The quality of the survey was verified by the Epidemiologic Survey Committee of the Korean Ophthalmologic Society. Training of participating residents was periodically performed by acting staff members of the National Epidemiologic Survey Committee of the Korean Ophthalmologic Society.


Cataract subtype risk factors identified from the Korea National Health and Nutrition Examination survey 2008-2010.

Rim TH, Kim MH, Kim WC, Kim TI, Kim EK - BMC Ophthalmol (2014)

Standard pictures for each subtype. A. Nuclear type, B. Cortical type, C. Anterior capsular type, D. Posterior capsular type.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3928645&req=5

Figure 3: Standard pictures for each subtype. A. Nuclear type, B. Cortical type, C. Anterior capsular type, D. Posterior capsular type.
Mentions: Designated ophthalmologists performed a structured slit-lamp examination (Haag-Streit model BQ-900, Haag-Streit AG, Koeniz, Switzerland) to determine disease occurrence in the anterior segment of the eye (e.g., pterygium and cataract). Examinees were seated in the examination chair, resting their chin and forehead on the support. An illuminator was positioned behind the examinees’ ears; the angle between the illuminator and the microscope was 30 ~ 45 degrees with a 10× magnification.Without iridodilator usage, the characteristics of lens were assessed using slit lamp with proper brightness, height, and width. The overall characteristics of the lens were examined with a wider slit lamp, and the type and severity of the cataract was determined according to transparency, turbidity, pigments, vacuoles and nuclei. Each layer of the lens was examined with the focused slit lamp from the anterior capsule to the posterior capsule. Aphakia and pseudophakia were recorded separately, and excluded from the subtype analysis. The type of cataract was categorized according to Lens Opacity Classification System III (LOCS III) grading in both eyes, as nuclear, cortical, PSCO, or mixed (including anterior subcapsular). Standard pictures for each subtype were provided for each examiner (Figure 3). The quality of the survey was verified by the Epidemiologic Survey Committee of the Korean Ophthalmologic Society. Training of participating residents was periodically performed by acting staff members of the National Epidemiologic Survey Committee of the Korean Ophthalmologic Society.

Bottom Line: Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts.Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts.Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Ophthalmology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, Korea. eungkkim@yuhs.ac.

ABSTRACT

Background: To assess the socio-demographic and health-related risk factors associated with cataract subtypes in Korea.

Methods: A total of 11,591 participants (aged ≥40 years) were selected from the Korean National Health and Nutrition Examination Survey between 2008 and 2010. The Korean Ophthalmologic Society conducted detailed ophthalmologic examinations on these participants based on the Lens Opacity Classification System III. Risk factors for developing any type of cataract, and its subtypes (nuclear, cortical, posterior subcapsular and mixed), were identified from univariate and multivariate logistic regression analysis.

Results: The prevalence of cataracts was 40.1% (95% CI, 37.8 - 42.3%) in participants over 40 years old. Older age, lower monthly household income, lower education, hypercholesterolemia, hypertension, and diabetes mellitus (DM) were independent risk factors for development of any cataract. Older age, lower monthly household income, lower education, hypercholesterolemia, and DM were independent risk factors for development of pure cortical cataracts. Older age, lower education, metabolic syndrome, and DM were independent risk factors for development of pure nuclear cataracts. Older age and DM were independent risk factors for development of pure posterior subcapsular cataracts. Older age, lower monthly household income, lower education, and DM were independent risk factors for development of mixed cataracts.

Conclusion: Although socioeconomic disparities are related to cataract development, this study identified several "modifiable" risk factors that may help to lower the incidence of cataracts and associated vision loss. Improved control of blood pressure, blood, glucose, and cholesterol may help to reduce the incidence of cataracts in the general Korean population.

Show MeSH
Related in: MedlinePlus