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Neuronal correlates of maladaptive coping: an EEG-study in tinnitus patients.

Vanneste S, Joos K, Langguth B, To WT, De Ridder D - PLoS ONE (2014)

Bottom Line: Based on resting state EEG recordings, coping related differences in brain activity and connectivity were found.Correlation analysis revealed that the changes in the DLPFC correlate primarily with maladaptive coping behavior, whereas the changes in the sgACC correlate with tinnitus severity and depression.Our findings are in line with previous research in the field of depression that during resting state a alpha band hyperconnectivity exists within the default network for patients who use a maladaptive coping style, with the sgACC as the dysfunctional node and that the strength of the connectivity is related to focusing on negative mood and catastrophizing about the consequences of tinnitus.

View Article: PubMed Central - PubMed

Affiliation: Department of Translational Neuroscience, Faculty of Medicine, University of Antwerp, Antwerp, Belgium ; School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, United States of America.

ABSTRACT
Here we aimed to investigate the neuronal correlates of different coping styles in patients suffering from chronic tinnitus. Adaptive and maladaptive coping styles were determined in 85 tinnitus patients. Based on resting state EEG recordings, coping related differences in brain activity and connectivity were found. Maladaptive coping behavior was related to increases in subjective tinnitus loudness and distress, higher tinnitus severity and higher depression scores. EEG recordings demonstrated increased alpha activity over the left dorsolateral prefrontal cortex (DLPFC) and subgenual anterior cingulate cortex (sgACC) as well as increased connectivity in the default (i.e. resting state) network in tinnitus patients with a maladaptive coping style. Correlation analysis revealed that the changes in the DLPFC correlate primarily with maladaptive coping behavior, whereas the changes in the sgACC correlate with tinnitus severity and depression. Our findings are in line with previous research in the field of depression that during resting state a alpha band hyperconnectivity exists within the default network for patients who use a maladaptive coping style, with the sgACC as the dysfunctional node and that the strength of the connectivity is related to focusing on negative mood and catastrophizing about the consequences of tinnitus.

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A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network.(A) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha1. (B) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha2.
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pone-0088253-g005: A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network.(A) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha1. (B) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha2.

Mentions: A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network (Figure 5 A & B) which also includes the sgACC. No significant effects were obtained for the other frequency bands (delta, theta, beta1, beta2, beta3 and gamma). Similar analyses were conducted between lagged phase coherence and BDI, TQ, VAS loudness, Age for alpha 1 and alpha2. These additional analyses revealed no significant effects.


Neuronal correlates of maladaptive coping: an EEG-study in tinnitus patients.

Vanneste S, Joos K, Langguth B, To WT, De Ridder D - PLoS ONE (2014)

A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network.(A) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha1. (B) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha2.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3928191&req=5

pone-0088253-g005: A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network.(A) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha1. (B) Increased functional connectivity (lagged phase synchronization) correlated with maladaptive behavior for the default network in Alpha2.
Mentions: A correlation analysis between lagged phase coherence and maladaptive coping behavior revealed significant effects for the alpha 1 and alpha2 default network (Figure 5 A & B) which also includes the sgACC. No significant effects were obtained for the other frequency bands (delta, theta, beta1, beta2, beta3 and gamma). Similar analyses were conducted between lagged phase coherence and BDI, TQ, VAS loudness, Age for alpha 1 and alpha2. These additional analyses revealed no significant effects.

Bottom Line: Based on resting state EEG recordings, coping related differences in brain activity and connectivity were found.Correlation analysis revealed that the changes in the DLPFC correlate primarily with maladaptive coping behavior, whereas the changes in the sgACC correlate with tinnitus severity and depression.Our findings are in line with previous research in the field of depression that during resting state a alpha band hyperconnectivity exists within the default network for patients who use a maladaptive coping style, with the sgACC as the dysfunctional node and that the strength of the connectivity is related to focusing on negative mood and catastrophizing about the consequences of tinnitus.

View Article: PubMed Central - PubMed

Affiliation: Department of Translational Neuroscience, Faculty of Medicine, University of Antwerp, Antwerp, Belgium ; School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, Texas, United States of America.

ABSTRACT
Here we aimed to investigate the neuronal correlates of different coping styles in patients suffering from chronic tinnitus. Adaptive and maladaptive coping styles were determined in 85 tinnitus patients. Based on resting state EEG recordings, coping related differences in brain activity and connectivity were found. Maladaptive coping behavior was related to increases in subjective tinnitus loudness and distress, higher tinnitus severity and higher depression scores. EEG recordings demonstrated increased alpha activity over the left dorsolateral prefrontal cortex (DLPFC) and subgenual anterior cingulate cortex (sgACC) as well as increased connectivity in the default (i.e. resting state) network in tinnitus patients with a maladaptive coping style. Correlation analysis revealed that the changes in the DLPFC correlate primarily with maladaptive coping behavior, whereas the changes in the sgACC correlate with tinnitus severity and depression. Our findings are in line with previous research in the field of depression that during resting state a alpha band hyperconnectivity exists within the default network for patients who use a maladaptive coping style, with the sgACC as the dysfunctional node and that the strength of the connectivity is related to focusing on negative mood and catastrophizing about the consequences of tinnitus.

Show MeSH
Related in: MedlinePlus