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A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010.

Liew G, Michaelides M, Bunce C - BMJ Open (2014)

Bottom Line: Between 1 April 1999 and 31 March 2000, the leading causes of blindness certification were diabetic retinopathy/maculopathy (17.7%), hereditary retinal disorders (15.8%) and optic atrophy (10.1%).For the first time in at least five decades, diabetic retinopathy/maculopathy is no longer the leading cause of certifiable blindness among working age adults in England and Wales, having been overtaken by inherited retinal disorders.Inherited retinal disease, now representing the commonest cause of certification in the working age population, has clinical and research implications, including with respect to the provision of care/resources in the NHS and the allocation of research funding.

View Article: PubMed Central - PubMed

Affiliation: Moorfields Eye Hospital NHS Foundation Trust, London, UK.

ABSTRACT

Objectives: To report on the causes of blindness certifications in England and Wales in working age adults (16-64 years) in 2009-2010; and to compare these with figures from 1999 to 2000.

Design: Analysis of the national database of blindness certificates of vision impairment (CVIs) received by the Certifications Office.

Setting and participants: Working age (16-64 years) population of England and Wales.

Main outcome measures: Number and cause of blindness certifications.

Results: The Certifications Office received 1756 CVIs for blindness from persons aged between 16 and 64 inclusive between 1 April 2009 and 31 March 2010. The main causes of blindness certifications were hereditary retinal disorders (354 certifications comprising 20.2% of the total), diabetic retinopathy/maculopathy (253 persons, 14.4%) and optic atrophy (248 persons, 14.1%). Together, these three leading causes accounted for almost 50% of all blindness certifications. Between 1 April 1999 and 31 March 2000, the leading causes of blindness certification were diabetic retinopathy/maculopathy (17.7%), hereditary retinal disorders (15.8%) and optic atrophy (10.1%).

Conclusions: For the first time in at least five decades, diabetic retinopathy/maculopathy is no longer the leading cause of certifiable blindness among working age adults in England and Wales, having been overtaken by inherited retinal disorders. This change may be related to factors including the introduction of nationwide diabetic retinopathy screening programmes in England and Wales and improved glycaemic control. Inherited retinal disease, now representing the commonest cause of certification in the working age population, has clinical and research implications, including with respect to the provision of care/resources in the NHS and the allocation of research funding.

No MeSH data available.


Related in: MedlinePlus

Ten-year change in causes of severe sight impairment (blindness) in England and Wales in working age adults (age 16–64): certifications 1999–2000 and 2009–2010.
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BMJOPEN2013004015F2: Ten-year change in causes of severe sight impairment (blindness) in England and Wales in working age adults (age 16–64): certifications 1999–2000 and 2009–2010.

Mentions: We next compared the main causes of blindness certifications from 1999 to 2000 (n=1637) with the figures above from 2009 to 2010 (n=1756). The results are shown graphically in figure 2. From 1999 to 2000, the leading cause of blindness certification was diabetic retinopathy/maculopathy, which accounted for 290 certifications (17.7%). By 2009–2010, this figure had decreased to 253 (14.4%), and diabetic retinopathy/maculopathy was now the second leading cause of blindness certification. This difference was statistically significant (p=0.009). In contrast, hereditary retinal disorders, which were the second leading cause of blindness certification in 1999–2000, accounting for 258 cases (15.8% of total), had increased to 354 cases (20.2%) by 2009–2010 and have now become the leading cause of certifiable blindness in the working age group in England and Wales. Optic atrophy remained the third leading cause in 1999–2000 and 2009–2010 with an increase from 165 cases (10.1%) to 248 cases (14.1%), respectively. A notable finding was that degeneration of the macula and posterior pole, which accounted for 7.7% of blindness registration in 1999–2000, had dropped in percentage terms and now accounted for only 3% by 2009–2010. Other causes of blindness registration remained roughly similar for the two time periods.


A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010.

Liew G, Michaelides M, Bunce C - BMJ Open (2014)

Ten-year change in causes of severe sight impairment (blindness) in England and Wales in working age adults (age 16–64): certifications 1999–2000 and 2009–2010.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3927710&req=5

BMJOPEN2013004015F2: Ten-year change in causes of severe sight impairment (blindness) in England and Wales in working age adults (age 16–64): certifications 1999–2000 and 2009–2010.
Mentions: We next compared the main causes of blindness certifications from 1999 to 2000 (n=1637) with the figures above from 2009 to 2010 (n=1756). The results are shown graphically in figure 2. From 1999 to 2000, the leading cause of blindness certification was diabetic retinopathy/maculopathy, which accounted for 290 certifications (17.7%). By 2009–2010, this figure had decreased to 253 (14.4%), and diabetic retinopathy/maculopathy was now the second leading cause of blindness certification. This difference was statistically significant (p=0.009). In contrast, hereditary retinal disorders, which were the second leading cause of blindness certification in 1999–2000, accounting for 258 cases (15.8% of total), had increased to 354 cases (20.2%) by 2009–2010 and have now become the leading cause of certifiable blindness in the working age group in England and Wales. Optic atrophy remained the third leading cause in 1999–2000 and 2009–2010 with an increase from 165 cases (10.1%) to 248 cases (14.1%), respectively. A notable finding was that degeneration of the macula and posterior pole, which accounted for 7.7% of blindness registration in 1999–2000, had dropped in percentage terms and now accounted for only 3% by 2009–2010. Other causes of blindness registration remained roughly similar for the two time periods.

Bottom Line: Between 1 April 1999 and 31 March 2000, the leading causes of blindness certification were diabetic retinopathy/maculopathy (17.7%), hereditary retinal disorders (15.8%) and optic atrophy (10.1%).For the first time in at least five decades, diabetic retinopathy/maculopathy is no longer the leading cause of certifiable blindness among working age adults in England and Wales, having been overtaken by inherited retinal disorders.Inherited retinal disease, now representing the commonest cause of certification in the working age population, has clinical and research implications, including with respect to the provision of care/resources in the NHS and the allocation of research funding.

View Article: PubMed Central - PubMed

Affiliation: Moorfields Eye Hospital NHS Foundation Trust, London, UK.

ABSTRACT

Objectives: To report on the causes of blindness certifications in England and Wales in working age adults (16-64 years) in 2009-2010; and to compare these with figures from 1999 to 2000.

Design: Analysis of the national database of blindness certificates of vision impairment (CVIs) received by the Certifications Office.

Setting and participants: Working age (16-64 years) population of England and Wales.

Main outcome measures: Number and cause of blindness certifications.

Results: The Certifications Office received 1756 CVIs for blindness from persons aged between 16 and 64 inclusive between 1 April 2009 and 31 March 2010. The main causes of blindness certifications were hereditary retinal disorders (354 certifications comprising 20.2% of the total), diabetic retinopathy/maculopathy (253 persons, 14.4%) and optic atrophy (248 persons, 14.1%). Together, these three leading causes accounted for almost 50% of all blindness certifications. Between 1 April 1999 and 31 March 2000, the leading causes of blindness certification were diabetic retinopathy/maculopathy (17.7%), hereditary retinal disorders (15.8%) and optic atrophy (10.1%).

Conclusions: For the first time in at least five decades, diabetic retinopathy/maculopathy is no longer the leading cause of certifiable blindness among working age adults in England and Wales, having been overtaken by inherited retinal disorders. This change may be related to factors including the introduction of nationwide diabetic retinopathy screening programmes in England and Wales and improved glycaemic control. Inherited retinal disease, now representing the commonest cause of certification in the working age population, has clinical and research implications, including with respect to the provision of care/resources in the NHS and the allocation of research funding.

No MeSH data available.


Related in: MedlinePlus