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Electroanalysis of NADH Using Conducting and Redox Active Polymer/Carbon Nanotubes Modified Electrodes-A Review

View Article: PubMed Central - PubMed

ABSTRACT

Past few decades, conducting and redox active polymers play a critical role in the development of transducers for biosensing. It has been evidenced by increasing numerous reports on conducting and redox active polymers incorporated electrodes for assay of biomolcules. This review highlights the potential uses of electrogenerated polymer modified electrodes and polymer/carbon nanotubes composite modified electrodes for electroanalysis of reduced form of nicotinamide adenine dinuceltoide (NADH). In addition, carbon electrodes modified with organic and inorganic materials as modifier have been discussed in detail for the quantification of NADH based on mediator or mediator-less methods.

No MeSH data available.


Related in: MedlinePlus

poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified GCE in the absences (curve a) and presences of 50μM NADH (curve b) in 0.1M phosphate buffer solution (pH 6.4).
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f1-sensors-08-00739: poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified GCE in the absences (curve a) and presences of 50μM NADH (curve b) in 0.1M phosphate buffer solution (pH 6.4).

Mentions: Electroanalysis of NADH has been studied using poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified glassy carbon electrode (PABS/FAD/GCE) in phosphate buffer solution (pH 6.4). Fig. 1 shows the electrocatalytic activity of PABS/FAD/GCE towards NADH, the highly amplified anodic peak current of polymer peak and decrease of cathodic peak indicates the mediated oxidation of NADH at lower potential. PABS/FAD/GCE has a fast response to NADH and a good linear response observed in the range from 10 to 300 μM. The detection limit is estimated to be 1μM (S/N = 3) [83]. However, poly(p-amino benzenesulfonic acid) film modified electrode also could be useful for simultaneous detection of dopamine and ascorbic acid [84].


Electroanalysis of NADH Using Conducting and Redox Active Polymer/Carbon Nanotubes Modified Electrodes-A Review
poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified GCE in the absences (curve a) and presences of 50μM NADH (curve b) in 0.1M phosphate buffer solution (pH 6.4).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3927499&req=5

f1-sensors-08-00739: poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified GCE in the absences (curve a) and presences of 50μM NADH (curve b) in 0.1M phosphate buffer solution (pH 6.4).
Mentions: Electroanalysis of NADH has been studied using poly(p-amino benzenesulfonic acid)/flavin adenine dinucleotide film modified glassy carbon electrode (PABS/FAD/GCE) in phosphate buffer solution (pH 6.4). Fig. 1 shows the electrocatalytic activity of PABS/FAD/GCE towards NADH, the highly amplified anodic peak current of polymer peak and decrease of cathodic peak indicates the mediated oxidation of NADH at lower potential. PABS/FAD/GCE has a fast response to NADH and a good linear response observed in the range from 10 to 300 μM. The detection limit is estimated to be 1μM (S/N = 3) [83]. However, poly(p-amino benzenesulfonic acid) film modified electrode also could be useful for simultaneous detection of dopamine and ascorbic acid [84].

View Article: PubMed Central - PubMed

ABSTRACT

Past few decades, conducting and redox active polymers play a critical role in the development of transducers for biosensing. It has been evidenced by increasing numerous reports on conducting and redox active polymers incorporated electrodes for assay of biomolcules. This review highlights the potential uses of electrogenerated polymer modified electrodes and polymer/carbon nanotubes composite modified electrodes for electroanalysis of reduced form of nicotinamide adenine dinuceltoide (NADH). In addition, carbon electrodes modified with organic and inorganic materials as modifier have been discussed in detail for the quantification of NADH based on mediator or mediator-less methods.

No MeSH data available.


Related in: MedlinePlus