Limits...
Comparative study on the microbiological features of angular cheilitis in HIV seropositive and HIV seronegative patients from South India.

Krishnan PA, Kannan R - J Oral Maxillofac Pathol (2013)

Bottom Line: This study was designed to compare the microbiological features of angular cheilitis (AC) in human immunodeficiency virus (HIV) seropositive and HIV seronegative individuals, in a group of south Indians.Candidal colonies were further speciated by the conventional biotyping technique.The present study suggests a definite difference in the microbial flora of AC in HIV seropositive patients than that of HIV seronegative population.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Pathology, College of Dentistry, Salman Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.

ABSTRACT

Objective: This study was designed to compare the microbiological features of angular cheilitis (AC) in human immunodeficiency virus (HIV) seropositive and HIV seronegative individuals, in a group of south Indians.

Materials and methods: Swabs from oral commissures of 46 patients were obtained and inoculated on to Sabouraud's dextrose agar (SDA) supplemented with chloramphenicol, blood agar (BA) and MacConkey's agar (MCA) plates and cultured. α-hemolytic Streptococci, Staphylococcus albus, Staphylococcus aureus, Candida species, Klebsiella species and Pseudomonas species were cultured. Candidal colonies were further speciated by the conventional biotyping technique.

Results: In AC of HIV seropositive patients Candida albicans and Staphylococcus aureus were more prevalent than that in HIV seronegative patients. Incidentally in patients with CD4 cell count less than 200 there was an increase in the incidence of Candidal and Staphylococcus aureus colonization when compared to patients with CD4 cell count higher than 200.

Conclusion: The present study suggests a definite difference in the microbial flora of AC in HIV seropositive patients than that of HIV seronegative population.

No MeSH data available.


Related in: MedlinePlus

Microbiology of angular cheilitis in 20 HIV seropositive patients. Staph albus: Staphylococcus albus, Staph aureus: Staphylococcus aureus, HIV: human immunodeficiency virus
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC3927333&req=5

Figure 4: Microbiology of angular cheilitis in 20 HIV seropositive patients. Staph albus: Staphylococcus albus, Staph aureus: Staphylococcus aureus, HIV: human immunodeficiency virus

Mentions: The male:female ratio of this group was 7:3. The age group of these patients ranged from 16 to 55 years. Staphylococcus albus was isolated from 45% of the patients. Staphylococcus aureus was isolated from 30% of the patients. Candida species was isolated from 65% of patients. Twenty-five percent of the patients showed mixed infection with Staphylococcus albus and Candida species. Mixed flora of Staphylococcus aureus and Candida species was seen in 5% of the patients [Graph 1]. Among the nine HIV seropositive patients who had CD4 cell count ≤200, Staphylococcus albus was isolated from 56% and Staphylococcus aureus was isolated from 45% of them. Candida species was isolated from 67% of the patients. About 45% of the patients showed mixed flora of Staphylococcus albus and Candida species. Eleven percent of the patients showed mixed flora of Staphylococcus aureus and Candida species. Three patients had mixed flora of Staphylococcus albus and Staphylococcus aureus. One patient with CD4 cell count of 84 showed colonization of Staphylococcus albus, Staphylococcus aureus and Candida species. Klebsiella species was isolated from a patient with CD4 cell count of 111 and Pseudomonas species colonies was found in one with CD4 cell count of 132. In patients with CD4 cell count of more than 200, Staphylococcus albus was isolated from 36%, Staphylococcus aureus was isolated from only 9%, while Candida species was isolated from 55% of them. Mixed infection of Staphylococcus albus and Candida species was found in 9% of the patients. None of them showed mixed flora of Staphylococcus aureus and Candida species [Graph 2].


Comparative study on the microbiological features of angular cheilitis in HIV seropositive and HIV seronegative patients from South India.

Krishnan PA, Kannan R - J Oral Maxillofac Pathol (2013)

Microbiology of angular cheilitis in 20 HIV seropositive patients. Staph albus: Staphylococcus albus, Staph aureus: Staphylococcus aureus, HIV: human immunodeficiency virus
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3927333&req=5

Figure 4: Microbiology of angular cheilitis in 20 HIV seropositive patients. Staph albus: Staphylococcus albus, Staph aureus: Staphylococcus aureus, HIV: human immunodeficiency virus
Mentions: The male:female ratio of this group was 7:3. The age group of these patients ranged from 16 to 55 years. Staphylococcus albus was isolated from 45% of the patients. Staphylococcus aureus was isolated from 30% of the patients. Candida species was isolated from 65% of patients. Twenty-five percent of the patients showed mixed infection with Staphylococcus albus and Candida species. Mixed flora of Staphylococcus aureus and Candida species was seen in 5% of the patients [Graph 1]. Among the nine HIV seropositive patients who had CD4 cell count ≤200, Staphylococcus albus was isolated from 56% and Staphylococcus aureus was isolated from 45% of them. Candida species was isolated from 67% of the patients. About 45% of the patients showed mixed flora of Staphylococcus albus and Candida species. Eleven percent of the patients showed mixed flora of Staphylococcus aureus and Candida species. Three patients had mixed flora of Staphylococcus albus and Staphylococcus aureus. One patient with CD4 cell count of 84 showed colonization of Staphylococcus albus, Staphylococcus aureus and Candida species. Klebsiella species was isolated from a patient with CD4 cell count of 111 and Pseudomonas species colonies was found in one with CD4 cell count of 132. In patients with CD4 cell count of more than 200, Staphylococcus albus was isolated from 36%, Staphylococcus aureus was isolated from only 9%, while Candida species was isolated from 55% of them. Mixed infection of Staphylococcus albus and Candida species was found in 9% of the patients. None of them showed mixed flora of Staphylococcus aureus and Candida species [Graph 2].

Bottom Line: This study was designed to compare the microbiological features of angular cheilitis (AC) in human immunodeficiency virus (HIV) seropositive and HIV seronegative individuals, in a group of south Indians.Candidal colonies were further speciated by the conventional biotyping technique.The present study suggests a definite difference in the microbial flora of AC in HIV seropositive patients than that of HIV seronegative population.

View Article: PubMed Central - PubMed

Affiliation: Department of Oral and Maxillofacial Pathology, College of Dentistry, Salman Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.

ABSTRACT

Objective: This study was designed to compare the microbiological features of angular cheilitis (AC) in human immunodeficiency virus (HIV) seropositive and HIV seronegative individuals, in a group of south Indians.

Materials and methods: Swabs from oral commissures of 46 patients were obtained and inoculated on to Sabouraud's dextrose agar (SDA) supplemented with chloramphenicol, blood agar (BA) and MacConkey's agar (MCA) plates and cultured. α-hemolytic Streptococci, Staphylococcus albus, Staphylococcus aureus, Candida species, Klebsiella species and Pseudomonas species were cultured. Candidal colonies were further speciated by the conventional biotyping technique.

Results: In AC of HIV seropositive patients Candida albicans and Staphylococcus aureus were more prevalent than that in HIV seronegative patients. Incidentally in patients with CD4 cell count less than 200 there was an increase in the incidence of Candidal and Staphylococcus aureus colonization when compared to patients with CD4 cell count higher than 200.

Conclusion: The present study suggests a definite difference in the microbial flora of AC in HIV seropositive patients than that of HIV seronegative population.

No MeSH data available.


Related in: MedlinePlus