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Alopecia universalis in polyglandular autoimmune syndrome type I.

Sardesai VR, Agarwal TD, Salampuria SN - Int J Trichology (2013)

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Deemed University Medical College, Pune, Maharashtra, India.

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Further enquiry and examination of her medical records revealed, she was a known case of polyglandular autoimmune syndrome-1 (PGA-1) with features of Addison's disease, hypoparathyrodism and type 1 diabetes mellitus... Tests for Serum calcium and phosphorus showed a value of 7 mg/dL and 13 mg/dL respectively... Level of ionized calcium was also reduced to 1 mmol/L... A diagnosis of PGA-1 with oral candidiasis and alopecia universalis was then made... Our patient presented with Addison's disease, oral candidiasis and hyperparathyroidism, all the three classical findings of PGA-1... In cases of PGA-1 alopecia has increasing prevalence in the middle age, it may present as transient patches of hair loss, whereas our patient presented with alopecia universalis... The prognosis of the patient is poor as there is no specific treatment modality available for PGA-1... Treatment is mainly symptomatic... Alopecia universalis occurring with PGA-1 is extremely rare... Only 10 cases have been reported in literature and no case reported from India.

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Related in: MedlinePlus

Facial pigmentation and absence of hair over eyebrows
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Figure 1: Facial pigmentation and absence of hair over eyebrows

Mentions: Dermatological examination revealed dry skin with increased facial pigmentation. There was absence of hair over the scalp, eyebrows, eyelashes, armpits and suprapubic region [Figures 1 and 2]. Oral examination revealed a curdy white plaque with a pseudomembrane over the tongue and buccal mucosa (suggestive of candidiasis). General and systemic examination showed no abnormality.


Alopecia universalis in polyglandular autoimmune syndrome type I.

Sardesai VR, Agarwal TD, Salampuria SN - Int J Trichology (2013)

Facial pigmentation and absence of hair over eyebrows
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3927181&req=5

Figure 1: Facial pigmentation and absence of hair over eyebrows
Mentions: Dermatological examination revealed dry skin with increased facial pigmentation. There was absence of hair over the scalp, eyebrows, eyelashes, armpits and suprapubic region [Figures 1 and 2]. Oral examination revealed a curdy white plaque with a pseudomembrane over the tongue and buccal mucosa (suggestive of candidiasis). General and systemic examination showed no abnormality.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, STD and Leprosy, Bharati Vidyapeeth Deemed University Medical College, Pune, Maharashtra, India.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

Further enquiry and examination of her medical records revealed, she was a known case of polyglandular autoimmune syndrome-1 (PGA-1) with features of Addison's disease, hypoparathyrodism and type 1 diabetes mellitus... Tests for Serum calcium and phosphorus showed a value of 7 mg/dL and 13 mg/dL respectively... Level of ionized calcium was also reduced to 1 mmol/L... A diagnosis of PGA-1 with oral candidiasis and alopecia universalis was then made... Our patient presented with Addison's disease, oral candidiasis and hyperparathyroidism, all the three classical findings of PGA-1... In cases of PGA-1 alopecia has increasing prevalence in the middle age, it may present as transient patches of hair loss, whereas our patient presented with alopecia universalis... The prognosis of the patient is poor as there is no specific treatment modality available for PGA-1... Treatment is mainly symptomatic... Alopecia universalis occurring with PGA-1 is extremely rare... Only 10 cases have been reported in literature and no case reported from India.

No MeSH data available.


Related in: MedlinePlus