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Is trichoscopy a reliable tool to diagnose early female pattern hair loss?

Bhamla SA, Dhurat RS, Saraogi PP - Int J Trichology (2013)

Bottom Line: This finding was significantly higher in FPHL Cases compared to normal controls.Trichoscopy was found to be 75% sensitive and 61.54% specific in diagnosing early FPHL.Thus, a negative result would be more indicative of absence of disease, however, a positive result would not always indicate the presence of disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, T.N.M. College and B.Y.L. Nair Ch. Hospital, Mumbai Central, Mumbai, Maharashtra, India.

ABSTRACT

Background: Female pattern hair loss (FPHL) presents with visible patterns of hair loss, thus making a bedside diagnosis possible. However, there are cases of FPHL presenting without any visible hair thinning, making it necessary to subject them to a scalp biopsy to make a diagnosis.

Aim: The aim of the following study is to determine if trichoscopy can be used as a bedside tool to diagnose Early FPHL in women presenting without any visible thinning of hair, using >20% hair diameter diversity - anisotrichosis, as the diagnostic criteria.

Materials and methods: Trichoscopy was performed on 20 cases of early FPHL (biopsy proven), 63 normal controls and 29 Grade 2 FPHL Controls.

Results and discussion: In the biopsy proven FPHL cases, 75% showed anisotrichosis on trichoscopy. This finding was significantly higher in FPHL Cases compared to normal controls. As expected, 93% of Grade 2 FPHL controls also showed the same finding. Trichoscopy was found to be 75% sensitive and 61.54% specific in diagnosing early FPHL. Thus, a negative result would be more indicative of absence of disease, however, a positive result would not always indicate the presence of disease.

No MeSH data available.


Related in: MedlinePlus

Group 2 control, Grade 2 female pattern hair loss, showing anisotrichosis on trichoscopy
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Figure 2: Group 2 control, Grade 2 female pattern hair loss, showing anisotrichosis on trichoscopy

Mentions: Amongst the cases, 75% of FPHL cases showed >20% HDD on trichoscopy [Figure 1], and as one would expect, 93% of Group 2 controls showed >20% HDD [Figure 2]. >20% HDD was significantly higher in FPHL compared to Group 1 control [Figure 3] (31.75%, P < 0.006) and CTE cases (38.5%, P < 0.036).


Is trichoscopy a reliable tool to diagnose early female pattern hair loss?

Bhamla SA, Dhurat RS, Saraogi PP - Int J Trichology (2013)

Group 2 control, Grade 2 female pattern hair loss, showing anisotrichosis on trichoscopy
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3927168&req=5

Figure 2: Group 2 control, Grade 2 female pattern hair loss, showing anisotrichosis on trichoscopy
Mentions: Amongst the cases, 75% of FPHL cases showed >20% HDD on trichoscopy [Figure 1], and as one would expect, 93% of Group 2 controls showed >20% HDD [Figure 2]. >20% HDD was significantly higher in FPHL compared to Group 1 control [Figure 3] (31.75%, P < 0.006) and CTE cases (38.5%, P < 0.036).

Bottom Line: This finding was significantly higher in FPHL Cases compared to normal controls.Trichoscopy was found to be 75% sensitive and 61.54% specific in diagnosing early FPHL.Thus, a negative result would be more indicative of absence of disease, however, a positive result would not always indicate the presence of disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, T.N.M. College and B.Y.L. Nair Ch. Hospital, Mumbai Central, Mumbai, Maharashtra, India.

ABSTRACT

Background: Female pattern hair loss (FPHL) presents with visible patterns of hair loss, thus making a bedside diagnosis possible. However, there are cases of FPHL presenting without any visible hair thinning, making it necessary to subject them to a scalp biopsy to make a diagnosis.

Aim: The aim of the following study is to determine if trichoscopy can be used as a bedside tool to diagnose Early FPHL in women presenting without any visible thinning of hair, using >20% hair diameter diversity - anisotrichosis, as the diagnostic criteria.

Materials and methods: Trichoscopy was performed on 20 cases of early FPHL (biopsy proven), 63 normal controls and 29 Grade 2 FPHL Controls.

Results and discussion: In the biopsy proven FPHL cases, 75% showed anisotrichosis on trichoscopy. This finding was significantly higher in FPHL Cases compared to normal controls. As expected, 93% of Grade 2 FPHL controls also showed the same finding. Trichoscopy was found to be 75% sensitive and 61.54% specific in diagnosing early FPHL. Thus, a negative result would be more indicative of absence of disease, however, a positive result would not always indicate the presence of disease.

No MeSH data available.


Related in: MedlinePlus