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Career guidance for stem cells

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ABSTRACT

BMP pathway spurs neuron progenitors to remain undifferentiated.

No MeSH data available.


Related in: MedlinePlus

FOCAL POINT (Left to right) Murielle Saade, Irene Gutiérrez-Vallejo, Elisa Martí, and Gwenvael Le Dréau probed the mechanism that controls division type in stem cells of the developing chick spinal cord. They found that two proteins in the BMP pathway, SMAD1 and SMAD5, hold back stem cells, inhibiting their differentiation into neurons. This transverse section of a 4-day-old chick embryo (right) captures neural progenitors (red) and differentiating neurons (blue).LAB PHOTO COURTESY OF MARTÍ LAB; IMAGE COURTESY OF GWENVAEL LE DRÉAU
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fig1: FOCAL POINT (Left to right) Murielle Saade, Irene Gutiérrez-Vallejo, Elisa Martí, and Gwenvael Le Dréau probed the mechanism that controls division type in stem cells of the developing chick spinal cord. They found that two proteins in the BMP pathway, SMAD1 and SMAD5, hold back stem cells, inhibiting their differentiation into neurons. This transverse section of a 4-day-old chick embryo (right) captures neural progenitors (red) and differentiating neurons (blue).LAB PHOTO COURTESY OF MARTÍ LAB; IMAGE COURTESY OF GWENVAEL LE DRÉAU


Career guidance for stem cells
FOCAL POINT (Left to right) Murielle Saade, Irene Gutiérrez-Vallejo, Elisa Martí, and Gwenvael Le Dréau probed the mechanism that controls division type in stem cells of the developing chick spinal cord. They found that two proteins in the BMP pathway, SMAD1 and SMAD5, hold back stem cells, inhibiting their differentiation into neurons. This transverse section of a 4-day-old chick embryo (right) captures neural progenitors (red) and differentiating neurons (blue).LAB PHOTO COURTESY OF MARTÍ LAB; IMAGE COURTESY OF GWENVAEL LE DRÉAU
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3926954&req=5

fig1: FOCAL POINT (Left to right) Murielle Saade, Irene Gutiérrez-Vallejo, Elisa Martí, and Gwenvael Le Dréau probed the mechanism that controls division type in stem cells of the developing chick spinal cord. They found that two proteins in the BMP pathway, SMAD1 and SMAD5, hold back stem cells, inhibiting their differentiation into neurons. This transverse section of a 4-day-old chick embryo (right) captures neural progenitors (red) and differentiating neurons (blue).LAB PHOTO COURTESY OF MARTÍ LAB; IMAGE COURTESY OF GWENVAEL LE DRÉAU

View Article: PubMed Central - HTML

ABSTRACT

BMP pathway spurs neuron progenitors to remain undifferentiated.

No MeSH data available.


Related in: MedlinePlus