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A case of adenosarcoma of the uterus.

Taga S, Sawada M, Nagai A, Yamamoto D, Hayase R - Case Rep Obstet Gynecol (2014)

Bottom Line: Cytological test of endometrium was performed but the result was negative.The lesion was confined to the uterus.Her postoperative course was uneventful and she was discharged without postoperative treatment and remains alive without disease 6 months after the surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama 720-0825, Japan.

ABSTRACT
Adenosarcoma is a rare tumor which consists of benign glandular epithelium and malignant mesenchymal component. Here we report a case of adenosarcoma of the uterine corpus. Case Presentation. A 59-year-old woman presented with vaginal bleeding and visited a local clinic. She had a uterine tumor pointed out and was referred to our hospital. Ultrasound scans revealed a large heterogeneous mass occupying the whole uterine cavity. Cytological test of endometrium was performed but the result was negative. A fractional endometrial curettage revealed no malignancy. Magnetic resonance imaging (MRI) revealed a heterogeneous solid tumor of 77 × 76 mm. Total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy was performed. On gross examination, the tumor was arising from the uterine body and occupied the whole uterine cavity. Histopathological examination revealed phyllodes-like architecture on low magnificationandperiglandular cuffing of tumor cells. The lesion was confined to the uterus. Histopathological final diagnosis was adenosarcoma. Her postoperative course was uneventful and she was discharged without postoperative treatment and remains alive without disease 6 months after the surgery.

No MeSH data available.


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(a) Phyllodes-like architecture on low magnification (H.E. ×100). (b) Periglandular cuffing of tumor cells (H.E. ×400).
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fig4: (a) Phyllodes-like architecture on low magnification (H.E. ×100). (b) Periglandular cuffing of tumor cells (H.E. ×400).

Mentions: At laparotomy, the uterus was fist size and no serosal invasion was observed. Both ovaries were intact. The tumor was arising from the uterine body and occupied the whole uterine cavity. Glandular epithelium with little atypia and proliferation of atypical mesenchymal cells were seen. Mitosis exceeded 2 per 10 high power fields. No myometrial invasion or lymph node metastasis was seen. The lesion was confined to the uterus. Peritoneal cytology revealed no malignant cells. Histopathological final diagnosis was adenosarcoma (Figure 4).


A case of adenosarcoma of the uterus.

Taga S, Sawada M, Nagai A, Yamamoto D, Hayase R - Case Rep Obstet Gynecol (2014)

(a) Phyllodes-like architecture on low magnification (H.E. ×100). (b) Periglandular cuffing of tumor cells (H.E. ×400).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3926369&req=5

fig4: (a) Phyllodes-like architecture on low magnification (H.E. ×100). (b) Periglandular cuffing of tumor cells (H.E. ×400).
Mentions: At laparotomy, the uterus was fist size and no serosal invasion was observed. Both ovaries were intact. The tumor was arising from the uterine body and occupied the whole uterine cavity. Glandular epithelium with little atypia and proliferation of atypical mesenchymal cells were seen. Mitosis exceeded 2 per 10 high power fields. No myometrial invasion or lymph node metastasis was seen. The lesion was confined to the uterus. Peritoneal cytology revealed no malignant cells. Histopathological final diagnosis was adenosarcoma (Figure 4).

Bottom Line: Cytological test of endometrium was performed but the result was negative.The lesion was confined to the uterus.Her postoperative course was uneventful and she was discharged without postoperative treatment and remains alive without disease 6 months after the surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Fukuyama Medical Center, Okinogamicho 4-14-17, Fukuyama 720-0825, Japan.

ABSTRACT
Adenosarcoma is a rare tumor which consists of benign glandular epithelium and malignant mesenchymal component. Here we report a case of adenosarcoma of the uterine corpus. Case Presentation. A 59-year-old woman presented with vaginal bleeding and visited a local clinic. She had a uterine tumor pointed out and was referred to our hospital. Ultrasound scans revealed a large heterogeneous mass occupying the whole uterine cavity. Cytological test of endometrium was performed but the result was negative. A fractional endometrial curettage revealed no malignancy. Magnetic resonance imaging (MRI) revealed a heterogeneous solid tumor of 77 × 76 mm. Total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy was performed. On gross examination, the tumor was arising from the uterine body and occupied the whole uterine cavity. Histopathological examination revealed phyllodes-like architecture on low magnificationandperiglandular cuffing of tumor cells. The lesion was confined to the uterus. Histopathological final diagnosis was adenosarcoma. Her postoperative course was uneventful and she was discharged without postoperative treatment and remains alive without disease 6 months after the surgery.

No MeSH data available.


Related in: MedlinePlus