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Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI).

Bruns K, Svensson F, Turkiewicz A, Wirth W, Guermazi A, Eckstein F, Englund M - BMC Musculoskelet Disord (2014)

Bottom Line: We calculated meniscal overlap distance on the tibial plateau, % coverage, and extrusion index compared to tibia width.Potential trends in position over the 4-year period were evaluated using a linear mixed-effects regression model.The other variables were relatively stable.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden. martin.englund@med.lu.se.

ABSTRACT

Background: A high degree of meniscal body extrusion on knee magnetic resonance imaging has been shown to be strongly associated with development of knee osteoarthritis. However, very little is known about meniscal position in the asymptomatic knee and its natural history. Hence our objective was to study meniscal body position and its change over 4 years in asymptomatic adults.

Methods: Cohort study using data from the Osteoarthritis Initiative (OAI) involving four clinical sites in the United States (Baltimore, Maryland, Pawtucket, Rhode Island, Columbus, Ohio, and Pittsburgh, Pennsylvania). We studied both knees from 118 subjects (mean age 55 years, 61% women, mean body mass index 24.4) from the OAI "non-exposed" reference cohort free of knee pain, radiographic knee osteoarthritis and risk factors for knee osteoarthritis at baseline. We assessed mid-coronal intermediate-weighted 3-Tesla magnetic resonance images from baseline and the 2- and 4-year follow-up visit. One observer measured tibia plateau, meniscal body width and meniscal body extrusion in both compartments. We calculated meniscal overlap distance on the tibial plateau, % coverage, and extrusion index compared to tibia width. Potential trends in position over the 4-year period were evaluated using a linear mixed-effects regression model.

Results: The mean (SD) values at baseline for medial meniscal body extrusion and overlap distance were 1.64 mm (0.92) and 10.1 mm (3.5), and coverage was 34.4% (11.9). The corresponding values for the lateral compartment were 0.63 mm (0.73), 9.8 mm (2.4), and 31.0% (7.7). Medial meniscus body extrusion index was greater in female knees (p = 0.03). There was slight increase in medial meniscal body extrusion over 4 years (0.040 mm/year [95% CI: 0.019-0.062]). The other variables were relatively stable.

Conclusions: In asymptomatic adults, the relative degree of meniscus body extrusion is more pronounced in female knees. Although a slight increase in extrusion over time was noted for the medial body, positions were relatively stable within subjects over time.

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Frequency of lateral coverage (% of ipsilateral tibia plateau width). Black bars illustrate the median value.
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Figure 6: Frequency of lateral coverage (% of ipsilateral tibia plateau width). Black bars illustrate the median value.

Mentions: Stratified by the presence of medial meniscal tear, we found a mean (SD) medial coverage of 29.0% (9.9) in the knees with medial tear vs. 34.8% (11.9) in knees without medial tear (p = 0.29) (Figure 5). In the lateral compartment we found a mean (SD) coverage of 25.2% (7.3) in knees with lateral meniscal tear, while those without lateral tear had a coverage of 31.3% (7.6) (p < 0.001) (Figure 6).


Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI).

Bruns K, Svensson F, Turkiewicz A, Wirth W, Guermazi A, Eckstein F, Englund M - BMC Musculoskelet Disord (2014)

Frequency of lateral coverage (% of ipsilateral tibia plateau width). Black bars illustrate the median value.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3924236&req=5

Figure 6: Frequency of lateral coverage (% of ipsilateral tibia plateau width). Black bars illustrate the median value.
Mentions: Stratified by the presence of medial meniscal tear, we found a mean (SD) medial coverage of 29.0% (9.9) in the knees with medial tear vs. 34.8% (11.9) in knees without medial tear (p = 0.29) (Figure 5). In the lateral compartment we found a mean (SD) coverage of 25.2% (7.3) in knees with lateral meniscal tear, while those without lateral tear had a coverage of 31.3% (7.6) (p < 0.001) (Figure 6).

Bottom Line: We calculated meniscal overlap distance on the tibial plateau, % coverage, and extrusion index compared to tibia width.Potential trends in position over the 4-year period were evaluated using a linear mixed-effects regression model.The other variables were relatively stable.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden. martin.englund@med.lu.se.

ABSTRACT

Background: A high degree of meniscal body extrusion on knee magnetic resonance imaging has been shown to be strongly associated with development of knee osteoarthritis. However, very little is known about meniscal position in the asymptomatic knee and its natural history. Hence our objective was to study meniscal body position and its change over 4 years in asymptomatic adults.

Methods: Cohort study using data from the Osteoarthritis Initiative (OAI) involving four clinical sites in the United States (Baltimore, Maryland, Pawtucket, Rhode Island, Columbus, Ohio, and Pittsburgh, Pennsylvania). We studied both knees from 118 subjects (mean age 55 years, 61% women, mean body mass index 24.4) from the OAI "non-exposed" reference cohort free of knee pain, radiographic knee osteoarthritis and risk factors for knee osteoarthritis at baseline. We assessed mid-coronal intermediate-weighted 3-Tesla magnetic resonance images from baseline and the 2- and 4-year follow-up visit. One observer measured tibia plateau, meniscal body width and meniscal body extrusion in both compartments. We calculated meniscal overlap distance on the tibial plateau, % coverage, and extrusion index compared to tibia width. Potential trends in position over the 4-year period were evaluated using a linear mixed-effects regression model.

Results: The mean (SD) values at baseline for medial meniscal body extrusion and overlap distance were 1.64 mm (0.92) and 10.1 mm (3.5), and coverage was 34.4% (11.9). The corresponding values for the lateral compartment were 0.63 mm (0.73), 9.8 mm (2.4), and 31.0% (7.7). Medial meniscus body extrusion index was greater in female knees (p = 0.03). There was slight increase in medial meniscal body extrusion over 4 years (0.040 mm/year [95% CI: 0.019-0.062]). The other variables were relatively stable.

Conclusions: In asymptomatic adults, the relative degree of meniscus body extrusion is more pronounced in female knees. Although a slight increase in extrusion over time was noted for the medial body, positions were relatively stable within subjects over time.

Show MeSH
Related in: MedlinePlus