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Plantago ovata consumption and colorectal mortality in Spain, 1995-2000.

López JC, Villanueva R, Martínez-Hernández D, Albaladejo R, Regidor E, Calle ME - J Epidemiol (2009)

Bottom Line: Associations were analyzed by calculating Spearman's correlation coefficients and a Poisson multiple regression model.In the Poisson regression analysis this tendency remained and reached statistical significance for the top quintile of P ovata consumption in the adjusted analysis (P = 0.042).We recommend additional observational studies of individuals, in order to better control confounding factors.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University, Madrid, Spain.

ABSTRACT

Background: Consumption of Plantago ovata may protect against colorectal cancer. To test this hypothesis, an ecological study was performed to determine mortality rates and distribution of colorectal cancer, and the consumption and distribution of P ovata, in different provinces in Spain. The putative association between P ovata consumption and mortality from colorectal cancer was then evaluated.

Methods: We conducted a comparative ecological study of Spanish provinces, with colorectal cancer mortality as the dependent variable and per capita consumption of P ovata by province and year as the independent variable. Associations were analyzed by calculating Spearman's correlation coefficients and a Poisson multiple regression model.

Results: Consumption of P ovata tended to be inversely correlated with mortality from colorectal cancer. In the Poisson regression analysis this tendency remained and reached statistical significance for the top quintile of P ovata consumption in the adjusted analysis (P = 0.042).

Conclusions: Our results show an inverse trend between the consumption of P ovata and colorectal cancer mortality. We recommend additional observational studies of individuals, in order to better control confounding factors.

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Related in: MedlinePlus

Mean annual mortality per 100 000 population in Spain, 1995–2000. Distribution in quintiles: <15.00; 15.00–19.99; 20.00–24.99; 25.00–29.99; >30.00
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fig01: Mean annual mortality per 100 000 population in Spain, 1995–2000. Distribution in quintiles: <15.00; 15.00–19.99; 20.00–24.99; 25.00–29.99; >30.00

Mentions: The mean adjusted mortality rate for colorectal cancer during the period from 1995 through 2000 was 22.93 per 100 000 population in men and 18.34 in women; the combined rate was 20.93. With respect to mean colorectal mortality rate per province for the study period (Figure 1), there was a north-to-south distribution (higher-to-lower mortality).


Plantago ovata consumption and colorectal mortality in Spain, 1995-2000.

López JC, Villanueva R, Martínez-Hernández D, Albaladejo R, Regidor E, Calle ME - J Epidemiol (2009)

Mean annual mortality per 100 000 population in Spain, 1995–2000. Distribution in quintiles: <15.00; 15.00–19.99; 20.00–24.99; 25.00–29.99; >30.00
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3924111&req=5

fig01: Mean annual mortality per 100 000 population in Spain, 1995–2000. Distribution in quintiles: <15.00; 15.00–19.99; 20.00–24.99; 25.00–29.99; >30.00
Mentions: The mean adjusted mortality rate for colorectal cancer during the period from 1995 through 2000 was 22.93 per 100 000 population in men and 18.34 in women; the combined rate was 20.93. With respect to mean colorectal mortality rate per province for the study period (Figure 1), there was a north-to-south distribution (higher-to-lower mortality).

Bottom Line: Associations were analyzed by calculating Spearman's correlation coefficients and a Poisson multiple regression model.In the Poisson regression analysis this tendency remained and reached statistical significance for the top quintile of P ovata consumption in the adjusted analysis (P = 0.042).We recommend additional observational studies of individuals, in order to better control confounding factors.

View Article: PubMed Central - PubMed

Affiliation: Department of Preventive Medicine and Public Health and History of Science, Faculty of Medicine, Complutense University, Madrid, Spain.

ABSTRACT

Background: Consumption of Plantago ovata may protect against colorectal cancer. To test this hypothesis, an ecological study was performed to determine mortality rates and distribution of colorectal cancer, and the consumption and distribution of P ovata, in different provinces in Spain. The putative association between P ovata consumption and mortality from colorectal cancer was then evaluated.

Methods: We conducted a comparative ecological study of Spanish provinces, with colorectal cancer mortality as the dependent variable and per capita consumption of P ovata by province and year as the independent variable. Associations were analyzed by calculating Spearman's correlation coefficients and a Poisson multiple regression model.

Results: Consumption of P ovata tended to be inversely correlated with mortality from colorectal cancer. In the Poisson regression analysis this tendency remained and reached statistical significance for the top quintile of P ovata consumption in the adjusted analysis (P = 0.042).

Conclusions: Our results show an inverse trend between the consumption of P ovata and colorectal cancer mortality. We recommend additional observational studies of individuals, in order to better control confounding factors.

Show MeSH
Related in: MedlinePlus