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Seven Years Trends in Prevalence of Transfusion-Transmissible Viral Infections in Yazd blood Transfusion Organization.

Javadzadeh Shahshahani H, Vaziri M, Mansouri F - Iran J Ped Hematol Oncol (2013)

Bottom Line: Increasing blood supply safety is one of the most important goals of blood services in the world.The prevalence rate of hepatitis B, C and HIV infection decreased during these years (From 0.37%, 0.14% and 0 percent in 2004 to 0.14%, 0.05% and 0 in 2010, respectively).The prevalence rate of hepatitis B was significantly higher in donors with less than 20 year-old and female donors.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

ABSTRACT

Background: Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran.

Materials and methods: In this cross sectional study, data on hepatitis B, C and HIV infection were extracted from Iranian Donor Database of blood donation from 2004 to 2010 in Yazd province. All donors with positive confirmatory test were included. The data was analyzed by SPSS software due to demographic factors.

Results: The prevalence rate of hepatitis B, C and HIV infection decreased during these years (From 0.37%, 0.14% and 0 percent in 2004 to 0.14%, 0.05% and 0 in 2010, respectively). Both hepatitis B and C infections were significantly more in first-time blood donors with BSc or BA educational level. The prevalence rate of hepatitis B was significantly higher in donors with less than 20 year-old and female donors. The prevalence rate of hepatitis C was higherin30-39 age group (P-value= 0.014).

Conclusion: The results showed that the strategies used for improving blood safety were efficient. Increasing public knowledge on blood-borne infections and their routes of transmission, importance of donating blood only by healthy donors are necessary to have a safe blood supply in future.

No MeSH data available.


Related in: MedlinePlus

Trends of HCV-Ab positive rate according to gender, marital status and donors' status
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Figure 3: Trends of HCV-Ab positive rate according to gender, marital status and donors' status

Mentions: During 2004 to 2010, 239 donors had confirmed positive test results for HCV-Ab. The trend of HCV-Ab positive test was decreasing (Fig 1).According to age, the 30-39 age group was the most prevalent group for HCV-Ab (P-value= 0.014). HCV-Ab positive donations were significantly more prevalent in BSc and BA and high school groups (P-value< 0.001) (Table I). The trend of HCV-Ab positive rate due to blood donor's status was decreasing (Fig 3). HCV-Ab prevalence rate was 205, 72 and 21 per105 donations of first time, lapsed and regular donors, respectively (P-value< 0.001).


Seven Years Trends in Prevalence of Transfusion-Transmissible Viral Infections in Yazd blood Transfusion Organization.

Javadzadeh Shahshahani H, Vaziri M, Mansouri F - Iran J Ped Hematol Oncol (2013)

Trends of HCV-Ab positive rate according to gender, marital status and donors' status
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3921874&req=5

Figure 3: Trends of HCV-Ab positive rate according to gender, marital status and donors' status
Mentions: During 2004 to 2010, 239 donors had confirmed positive test results for HCV-Ab. The trend of HCV-Ab positive test was decreasing (Fig 1).According to age, the 30-39 age group was the most prevalent group for HCV-Ab (P-value= 0.014). HCV-Ab positive donations were significantly more prevalent in BSc and BA and high school groups (P-value< 0.001) (Table I). The trend of HCV-Ab positive rate due to blood donor's status was decreasing (Fig 3). HCV-Ab prevalence rate was 205, 72 and 21 per105 donations of first time, lapsed and regular donors, respectively (P-value< 0.001).

Bottom Line: Increasing blood supply safety is one of the most important goals of blood services in the world.The prevalence rate of hepatitis B, C and HIV infection decreased during these years (From 0.37%, 0.14% and 0 percent in 2004 to 0.14%, 0.05% and 0 in 2010, respectively).The prevalence rate of hepatitis B was significantly higher in donors with less than 20 year-old and female donors.

View Article: PubMed Central - PubMed

Affiliation: Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

ABSTRACT

Background: Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran.

Materials and methods: In this cross sectional study, data on hepatitis B, C and HIV infection were extracted from Iranian Donor Database of blood donation from 2004 to 2010 in Yazd province. All donors with positive confirmatory test were included. The data was analyzed by SPSS software due to demographic factors.

Results: The prevalence rate of hepatitis B, C and HIV infection decreased during these years (From 0.37%, 0.14% and 0 percent in 2004 to 0.14%, 0.05% and 0 in 2010, respectively). Both hepatitis B and C infections were significantly more in first-time blood donors with BSc or BA educational level. The prevalence rate of hepatitis B was significantly higher in donors with less than 20 year-old and female donors. The prevalence rate of hepatitis C was higherin30-39 age group (P-value= 0.014).

Conclusion: The results showed that the strategies used for improving blood safety were efficient. Increasing public knowledge on blood-borne infections and their routes of transmission, importance of donating blood only by healthy donors are necessary to have a safe blood supply in future.

No MeSH data available.


Related in: MedlinePlus