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Metastatic malignant melanoma of the urinary bladder: Case report and literature review.

Paterson A, Sut M, Kaul A, Altieri V, Mutch F, Patel J, Sharma H - Cent European J Urol (2012)

Bottom Line: Metastatic malignant melanoma of the urinary bladder is a rare clinical finding suggestive of advanced disease.Only 17 cases have been described in the English literature.We present a case of an 84-year-old male who was referred to the urology department with the incidental finding of bladder metastases on computed tomography (CT) one year following the diagnosis of malignant melanoma of the skin.

View Article: PubMed Central - PubMed

Affiliation: Bedford Hospital, Department of Urology, Bedfordshire, United Kingdom.

ABSTRACT
Metastatic malignant melanoma of the urinary bladder is a rare clinical finding suggestive of advanced disease. Only 17 cases have been described in the English literature. We present a case of an 84-year-old male who was referred to the urology department with the incidental finding of bladder metastases on computed tomography (CT) one year following the diagnosis of malignant melanoma of the skin. Herein, we will discuss epidemiology, prognosis, and management options of metastatic malignant melanoma based on literature review.

No MeSH data available.


Related in: MedlinePlus

HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).
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Figure 0005: HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).

Mentions: During a flexible cystoscopy performed in September 2011, multiple pigmented lesions were identified within the bladder (Figs. 2 and 3). Urine cytology revealed a number of scattered single cells containing pigment, positive for S100 and HMB45, and negative for Perl's stain for iron (Figs. 4 and 5). A diagnosis of stage IV metastatic malignant melanoma with bladder involvement was made. Due to the general poor condition of the patient, the multidisciplinary team consensus was against active treatment. The patient deteriorated rapidly and died due to respiratory compromise.


Metastatic malignant melanoma of the urinary bladder: Case report and literature review.

Paterson A, Sut M, Kaul A, Altieri V, Mutch F, Patel J, Sharma H - Cent European J Urol (2012)

HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3921808&req=5

Figure 0005: HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).
Mentions: During a flexible cystoscopy performed in September 2011, multiple pigmented lesions were identified within the bladder (Figs. 2 and 3). Urine cytology revealed a number of scattered single cells containing pigment, positive for S100 and HMB45, and negative for Perl's stain for iron (Figs. 4 and 5). A diagnosis of stage IV metastatic malignant melanoma with bladder involvement was made. Due to the general poor condition of the patient, the multidisciplinary team consensus was against active treatment. The patient deteriorated rapidly and died due to respiratory compromise.

Bottom Line: Metastatic malignant melanoma of the urinary bladder is a rare clinical finding suggestive of advanced disease.Only 17 cases have been described in the English literature.We present a case of an 84-year-old male who was referred to the urology department with the incidental finding of bladder metastases on computed tomography (CT) one year following the diagnosis of malignant melanoma of the skin.

View Article: PubMed Central - PubMed

Affiliation: Bedford Hospital, Department of Urology, Bedfordshire, United Kingdom.

ABSTRACT
Metastatic malignant melanoma of the urinary bladder is a rare clinical finding suggestive of advanced disease. Only 17 cases have been described in the English literature. We present a case of an 84-year-old male who was referred to the urology department with the incidental finding of bladder metastases on computed tomography (CT) one year following the diagnosis of malignant melanoma of the skin. Herein, we will discuss epidemiology, prognosis, and management options of metastatic malignant melanoma based on literature review.

No MeSH data available.


Related in: MedlinePlus