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A case of metastatic prostate adenocarcinoma to an inguinal lymph node.

Komeya M, Sahoda T, Sugiura S, Sawada T, Kitami K - Cent European J Urol (2012)

Bottom Line: A computed tomography scan showed left inguinal lymphadenopathy.Biopsy of the swollen inguinal lymph node revealed metastatic prostate cancer.We report a rare case of metastatic prostate adenocarcinoma only to the inguinal lymph nodes.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Fujisawa City Hospital, Kanagawa, Japan.

ABSTRACT
A 47-year-old man presented with dysuria. The prostate-specific antigen level was 65.5 ng/mL. Retropubic radical prostatectomy and regional lymphadenectomy revealed moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7, pT2N0). Postoperative adjuvant hormonal therapy was started immediately. Three years later, hormonal therapy was changed to anti-androgen monotherapy. Monotherapy was continued for eight years and then discontinued because the PSA level was maintained at <0.04 ng/mL. However, biochemical recurrence occurred 12 months after adjuvant hormonal therapy was discontinued. A computed tomography scan showed left inguinal lymphadenopathy. Biopsy of the swollen inguinal lymph node revealed metastatic prostate cancer. We report a rare case of metastatic prostate adenocarcinoma only to the inguinal lymph nodes.

No MeSH data available.


Related in: MedlinePlus

A. (left), Histopathological examination shows moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (H & E staining, ×200). B. (right), The biopsy of the swollen inguinal lymph node shows adenocarcinoma. The tumor cell cytoplasm shows vacuolar degeneration (H & E staining, ×200).
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Figure 0001: A. (left), Histopathological examination shows moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (H & E staining, ×200). B. (right), The biopsy of the swollen inguinal lymph node shows adenocarcinoma. The tumor cell cytoplasm shows vacuolar degeneration (H & E staining, ×200).

Mentions: A 47-year-old man presented with dysuria. Digital rectal examination revealed a nodule in the left lobe of the prostate. The prostate-specific antigen (PSA) level was 65.5 ng/mL. Transrectal biopsy of the prostate revealed adenocarcinoma. A computed tomography (CT) scan, magnetic resonance imaging, and bone scan showed no metastasis. After two months of neoadjuvant hormonal therapy (leuproreline and bicalutamide), retropubic radical prostatectomy and obturator lymph node dissection were performed. The pathological finding was a moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (Fig. 1A). The surgical margins and obturator lymph nodes were negative.


A case of metastatic prostate adenocarcinoma to an inguinal lymph node.

Komeya M, Sahoda T, Sugiura S, Sawada T, Kitami K - Cent European J Urol (2012)

A. (left), Histopathological examination shows moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (H & E staining, ×200). B. (right), The biopsy of the swollen inguinal lymph node shows adenocarcinoma. The tumor cell cytoplasm shows vacuolar degeneration (H & E staining, ×200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3921775&req=5

Figure 0001: A. (left), Histopathological examination shows moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (H & E staining, ×200). B. (right), The biopsy of the swollen inguinal lymph node shows adenocarcinoma. The tumor cell cytoplasm shows vacuolar degeneration (H & E staining, ×200).
Mentions: A 47-year-old man presented with dysuria. Digital rectal examination revealed a nodule in the left lobe of the prostate. The prostate-specific antigen (PSA) level was 65.5 ng/mL. Transrectal biopsy of the prostate revealed adenocarcinoma. A computed tomography (CT) scan, magnetic resonance imaging, and bone scan showed no metastasis. After two months of neoadjuvant hormonal therapy (leuproreline and bicalutamide), retropubic radical prostatectomy and obturator lymph node dissection were performed. The pathological finding was a moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7) (Fig. 1A). The surgical margins and obturator lymph nodes were negative.

Bottom Line: A computed tomography scan showed left inguinal lymphadenopathy.Biopsy of the swollen inguinal lymph node revealed metastatic prostate cancer.We report a rare case of metastatic prostate adenocarcinoma only to the inguinal lymph nodes.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Fujisawa City Hospital, Kanagawa, Japan.

ABSTRACT
A 47-year-old man presented with dysuria. The prostate-specific antigen level was 65.5 ng/mL. Retropubic radical prostatectomy and regional lymphadenectomy revealed moderately differentiated adenocarcinoma (Gleason score 3 + 4 = 7, pT2N0). Postoperative adjuvant hormonal therapy was started immediately. Three years later, hormonal therapy was changed to anti-androgen monotherapy. Monotherapy was continued for eight years and then discontinued because the PSA level was maintained at <0.04 ng/mL. However, biochemical recurrence occurred 12 months after adjuvant hormonal therapy was discontinued. A computed tomography scan showed left inguinal lymphadenopathy. Biopsy of the swollen inguinal lymph node revealed metastatic prostate cancer. We report a rare case of metastatic prostate adenocarcinoma only to the inguinal lymph nodes.

No MeSH data available.


Related in: MedlinePlus