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Alkaline cystitis - a delayed presentation post transurethral resection of prostate. A case discussion and literature review.

Khan FR, Katmawi-Sabbagh S, England R, Al-Sudani M, Khan SZ - Cent European J Urol (2012)

Bottom Line: It is rare now because of appropriate antibiotics.It is a challenging situation with regard to its diagnosis and management.The management includes careful acidification of urine, curettage of calcified material, and appropriate antibiotics.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Kettering General Hospital, Kettering Northampshire, United Kingdom.

ABSTRACT
Alkaline encrusted cystitis is a chronic inflammatory condition. It is rare now because of appropriate antibiotics. It is a challenging situation with regard to its diagnosis and management. We are presenting an interesting case of alkaline cystitis post transurethral resection of prostate. The management includes careful acidification of urine, curettage of calcified material, and appropriate antibiotics.

No MeSH data available.


Related in: MedlinePlus

Bladder mucosa showing surface ulceration, severe acute and chronic inflammation down to muscularis.
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Figure 0003: Bladder mucosa showing surface ulceration, severe acute and chronic inflammation down to muscularis.

Mentions: A 63 year-old male was admitted with suprapubic pain, intermittent hematuria and passage of sandy grits in the urine. His past medical history notable for a TURP two years previously at which time the bladder was normal. Physical examination was unremarkable. A CT scan showed multiple calcifications covering the surface of the bladder with bilateral hydronephrosis (Fig. 1, 2). Cystoscopy demonstrated a small capacity bladder with a necrotic looking urothelium and extensive calcifications adherent to the bladder wall. A bladder biopsy and the curettage (bladder scrapping with loop resection) of calcifications were sent for examination. Histology demonstrated extensive urothelial ulceration, necrosis and nonspecific active chronic inflammation with foci of interstitial calcification (Fig. 3, 4). Analysis of bladder calcifications revealed magnesium ammonium phosphate. Urine pH was alkaline at 8.4. These findings were suggestive of alkaline cystitis. Urine culture grew proteus and the curettage grew corynebacterium urealyticum.


Alkaline cystitis - a delayed presentation post transurethral resection of prostate. A case discussion and literature review.

Khan FR, Katmawi-Sabbagh S, England R, Al-Sudani M, Khan SZ - Cent European J Urol (2012)

Bladder mucosa showing surface ulceration, severe acute and chronic inflammation down to muscularis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3921767&req=5

Figure 0003: Bladder mucosa showing surface ulceration, severe acute and chronic inflammation down to muscularis.
Mentions: A 63 year-old male was admitted with suprapubic pain, intermittent hematuria and passage of sandy grits in the urine. His past medical history notable for a TURP two years previously at which time the bladder was normal. Physical examination was unremarkable. A CT scan showed multiple calcifications covering the surface of the bladder with bilateral hydronephrosis (Fig. 1, 2). Cystoscopy demonstrated a small capacity bladder with a necrotic looking urothelium and extensive calcifications adherent to the bladder wall. A bladder biopsy and the curettage (bladder scrapping with loop resection) of calcifications were sent for examination. Histology demonstrated extensive urothelial ulceration, necrosis and nonspecific active chronic inflammation with foci of interstitial calcification (Fig. 3, 4). Analysis of bladder calcifications revealed magnesium ammonium phosphate. Urine pH was alkaline at 8.4. These findings were suggestive of alkaline cystitis. Urine culture grew proteus and the curettage grew corynebacterium urealyticum.

Bottom Line: It is rare now because of appropriate antibiotics.It is a challenging situation with regard to its diagnosis and management.The management includes careful acidification of urine, curettage of calcified material, and appropriate antibiotics.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, Kettering General Hospital, Kettering Northampshire, United Kingdom.

ABSTRACT
Alkaline encrusted cystitis is a chronic inflammatory condition. It is rare now because of appropriate antibiotics. It is a challenging situation with regard to its diagnosis and management. We are presenting an interesting case of alkaline cystitis post transurethral resection of prostate. The management includes careful acidification of urine, curettage of calcified material, and appropriate antibiotics.

No MeSH data available.


Related in: MedlinePlus