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Tolerance of natural baby skin-care products on healthy, full-term infants and toddlers.

Coret CD, Suero MB, Tierney NK - Clin Cosmet Investig Dermatol (2014)

Bottom Line: No significant changes in clinical grading scores were observed, indicating that all products were well tolerated.In study 2, there were no product-related adverse events.The natural baby skin-care products were well tolerated by infants and toddlers when used alone or as part of a skin-care regimen.

View Article: PubMed Central - PubMed

Affiliation: Johnson & Johnson Consumer Companies, Inc, Skillman, NJ, USA.

ABSTRACT

Purpose: To evaluate the tolerance of baby skin-care products with at least 95% naturally derived ingredients on infants and toddlers.

Materials and methods: Healthy, full-term infants and toddlers aged 1-36 months were enrolled. In study 1, a lightly fragranced natural baby hair and body wash (n=30), a lightly fragranced natural baby shampoo (n=30), or a lightly fragranced natural baby lotion (n=32) were assessed over 2 weeks. In study 2, a lightly fragranced natural baby hair and body wash and a lightly fragranced natural baby lotion (n=33) were assessed as a regimen over 4 weeks. The wash and shampoo were used three or more times per week, but not more than once daily. Lotions were applied in the morning or after a bath. Clinicians assessed the arms, legs, torso, or scalp for erythema, dryness, peeling/flakiness (study 1 only), tactile roughness, edema (study 1 only), rash/irritation (study 2 only), and overall skin condition (study 2 only) at baseline, week 1, and weeks 2 or 4. Parents completed skin assessment questionnaires. In study 2, stratum corneum hydration was measured. Subjects were monitored for adverse events.

Results: No significant changes in clinical grading scores were observed, indicating that all products were well tolerated. By the end of each study, >90% of parents/caregivers believed each product was mild and gentle. In study 2, improvement in stratum corneum hydration was observed (+37% at week 1 and +48% at week 4, P<0.05 for both). In study 1, one baby experienced mild erythema on the neck and scalp after using the shampoo (possibly related to treatment). In study 2, there were no product-related adverse events.

Conclusion: The natural baby skin-care products were well tolerated by infants and toddlers when used alone or as part of a skin-care regimen.

No MeSH data available.


Related in: MedlinePlus

Stratum corneum hydration measurements following 4 weeks of skin-care regimen (study 2).Notes: *P<0.05 versus baseline. There was a statistically significant improvement in stratum corneum hydration on the right lower outer leg at weeks 1 and 4 compared with baseline. Data shown are means ± standard error of the mean of Corneometer measurements.
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f3-ccid-7-051: Stratum corneum hydration measurements following 4 weeks of skin-care regimen (study 2).Notes: *P<0.05 versus baseline. There was a statistically significant improvement in stratum corneum hydration on the right lower outer leg at weeks 1 and 4 compared with baseline. Data shown are means ± standard error of the mean of Corneometer measurements.

Mentions: In study 2, use of the natural skin-care regimen led to a significant improvement in SCH at weeks 1 and 4 compared with that at baseline (Figure 3).


Tolerance of natural baby skin-care products on healthy, full-term infants and toddlers.

Coret CD, Suero MB, Tierney NK - Clin Cosmet Investig Dermatol (2014)

Stratum corneum hydration measurements following 4 weeks of skin-care regimen (study 2).Notes: *P<0.05 versus baseline. There was a statistically significant improvement in stratum corneum hydration on the right lower outer leg at weeks 1 and 4 compared with baseline. Data shown are means ± standard error of the mean of Corneometer measurements.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3921078&req=5

f3-ccid-7-051: Stratum corneum hydration measurements following 4 weeks of skin-care regimen (study 2).Notes: *P<0.05 versus baseline. There was a statistically significant improvement in stratum corneum hydration on the right lower outer leg at weeks 1 and 4 compared with baseline. Data shown are means ± standard error of the mean of Corneometer measurements.
Mentions: In study 2, use of the natural skin-care regimen led to a significant improvement in SCH at weeks 1 and 4 compared with that at baseline (Figure 3).

Bottom Line: No significant changes in clinical grading scores were observed, indicating that all products were well tolerated.In study 2, there were no product-related adverse events.The natural baby skin-care products were well tolerated by infants and toddlers when used alone or as part of a skin-care regimen.

View Article: PubMed Central - PubMed

Affiliation: Johnson & Johnson Consumer Companies, Inc, Skillman, NJ, USA.

ABSTRACT

Purpose: To evaluate the tolerance of baby skin-care products with at least 95% naturally derived ingredients on infants and toddlers.

Materials and methods: Healthy, full-term infants and toddlers aged 1-36 months were enrolled. In study 1, a lightly fragranced natural baby hair and body wash (n=30), a lightly fragranced natural baby shampoo (n=30), or a lightly fragranced natural baby lotion (n=32) were assessed over 2 weeks. In study 2, a lightly fragranced natural baby hair and body wash and a lightly fragranced natural baby lotion (n=33) were assessed as a regimen over 4 weeks. The wash and shampoo were used three or more times per week, but not more than once daily. Lotions were applied in the morning or after a bath. Clinicians assessed the arms, legs, torso, or scalp for erythema, dryness, peeling/flakiness (study 1 only), tactile roughness, edema (study 1 only), rash/irritation (study 2 only), and overall skin condition (study 2 only) at baseline, week 1, and weeks 2 or 4. Parents completed skin assessment questionnaires. In study 2, stratum corneum hydration was measured. Subjects were monitored for adverse events.

Results: No significant changes in clinical grading scores were observed, indicating that all products were well tolerated. By the end of each study, >90% of parents/caregivers believed each product was mild and gentle. In study 2, improvement in stratum corneum hydration was observed (+37% at week 1 and +48% at week 4, P<0.05 for both). In study 1, one baby experienced mild erythema on the neck and scalp after using the shampoo (possibly related to treatment). In study 2, there were no product-related adverse events.

Conclusion: The natural baby skin-care products were well tolerated by infants and toddlers when used alone or as part of a skin-care regimen.

No MeSH data available.


Related in: MedlinePlus