Laparoscopic versus open liver resection: a meta-analysis of long-term outcome.
Bottom Line: Subset analyses of hepatocellular carcinoma (HCC) and colorectal metastases (CRM) were performed.There was no difference in the 1-, 3-, and 5-year survival for HCC or in the 1-year survival for CRM, however, a survival advantage was found for CRM at 3 years (LHep 80% versus OHep 67.4%, P = 0.036).Laparoscopic surgery should be considered an acceptable alternative for the treatment of malignant liver tumours.
Affiliation: Department of Surgery, Jersey Shore University Medical Center; Department of Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.Show MeSH
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Mentions: The primary literature search garnered a total of 1091 abstracts. After review, abstracts were then narrowed down to 37 articles that compared LHep and OHep for solid liver tumours. Twenty studies were excluded from the analysis owing to the omission of survival data. Of the remaining 17 articles, 2 articles15,16 were found to, after contact with the respective authors, contain data from patients that were reported again in more recent studies.17,18 These more recent studies contained additional data on long-term results and thus are included in this meta-analysis. In total, 15 articles were identified to meet inclusion criteria for this meta-analysis17–31 (see Fig. 1).
Affiliation: Department of Surgery, Jersey Shore University Medical Center; Department of Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.