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Oral malignant melanoma detected after resection of amelanotic pulmonary metastasis.

Matsuoka K - Int J Surg Case Rep (2013)

Bottom Line: A detailed physical examination revealed a black tumor in the oral cavity, and this was suspected to have been the primary.Because of absence of symptoms in the early stage of the disease and the presence of the tumor in relatively obscure areas of the oral cavity, the diagnosis is unfortunately often delayed.In view of the rarity of primary lung melanoma, when lung tumor was diagnosed as malignant melanoma, detailed physical examination of the entire skin and mucosa including the oral cavity was necessary.

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Surgery, National Hospital Organization Himeji Medical Center, 670-8520 Honmachi 68, Himeji-City, Hyogo, Japan. Electronic address: katccha@ares.eonet.ne.jp.

No MeSH data available.


Related in: MedlinePlus

Slightly elevated black lesions with irregular boundaries approximately 20 mm in diameter was detected on the palatal mucosa.
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fig0015: Slightly elevated black lesions with irregular boundaries approximately 20 mm in diameter was detected on the palatal mucosa.

Mentions: Because primary pulmonary malignant melanoma was extremely rare, the tumor was thought to be a metastasized from an occult primary lesion. A whole skin examination showed no abnormal findings. However, examination in oral cavity revealed slightly elevated, black lesions with irregular boundaries approximately 20 mm in diameter on the palatal mucosa (Fig. 3). The patient had not been aware of this lesion. An incisional biopsy was performed under local anesthesia, and the tumor was diagnosed as malignant melanoma. Resection of the hard palate tumor and dissection of the cervical lymph nodes were performed at the department of otolaryngology of our institute. Although the melanoma was at an advanced stage, the patient was simply followed up without further chemotherapy or immunotherapy at his request, and he died one year after surgery due to bleeding from a pleural metastasis of malignant melanoma.


Oral malignant melanoma detected after resection of amelanotic pulmonary metastasis.

Matsuoka K - Int J Surg Case Rep (2013)

Slightly elevated black lesions with irregular boundaries approximately 20 mm in diameter was detected on the palatal mucosa.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3860044&req=5

fig0015: Slightly elevated black lesions with irregular boundaries approximately 20 mm in diameter was detected on the palatal mucosa.
Mentions: Because primary pulmonary malignant melanoma was extremely rare, the tumor was thought to be a metastasized from an occult primary lesion. A whole skin examination showed no abnormal findings. However, examination in oral cavity revealed slightly elevated, black lesions with irregular boundaries approximately 20 mm in diameter on the palatal mucosa (Fig. 3). The patient had not been aware of this lesion. An incisional biopsy was performed under local anesthesia, and the tumor was diagnosed as malignant melanoma. Resection of the hard palate tumor and dissection of the cervical lymph nodes were performed at the department of otolaryngology of our institute. Although the melanoma was at an advanced stage, the patient was simply followed up without further chemotherapy or immunotherapy at his request, and he died one year after surgery due to bleeding from a pleural metastasis of malignant melanoma.

Bottom Line: A detailed physical examination revealed a black tumor in the oral cavity, and this was suspected to have been the primary.Because of absence of symptoms in the early stage of the disease and the presence of the tumor in relatively obscure areas of the oral cavity, the diagnosis is unfortunately often delayed.In view of the rarity of primary lung melanoma, when lung tumor was diagnosed as malignant melanoma, detailed physical examination of the entire skin and mucosa including the oral cavity was necessary.

View Article: PubMed Central - PubMed

Affiliation: Department of Thoracic Surgery, National Hospital Organization Himeji Medical Center, 670-8520 Honmachi 68, Himeji-City, Hyogo, Japan. Electronic address: katccha@ares.eonet.ne.jp.

No MeSH data available.


Related in: MedlinePlus