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Primary hepatic lymphoma: A case report.

Resende V, Oliveira TS, Gomes RT, Laboissière RS, Tavares-Junior WC, de Melo Couto OF - Int J Surg Case Rep (2013)

Bottom Line: It is important to recognize PHL because it responds favorably to chemotherapy and may have a better prognosis than hepatocellular carcinoma or metastatic disease of the liver.This type of lesion is highly chemosensitive and early aggressive chemotherapy may result in sustained remission.This case emphasizes the importance of effective recognition of PHL considering its good response to chemotherapy and the possibility of sustained remission if early aggressive treatment is implemented.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, School of Medicine, The Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: vivianresen@gmail.com.

No MeSH data available.


Related in: MedlinePlus

Histopathology of the liver biopsy shows (a) normal hepatocytes and tumor cells (H&E, 100×) and (b) infiltration of large lymphoid cells (H&E, 400×), (c) positive CD45-LCA (100×), (d) positive cytokeratin in normal hepatocytes (100×), (e) positive Ki67 (400×) and (f) positive CD20 (400×).
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fig0010: Histopathology of the liver biopsy shows (a) normal hepatocytes and tumor cells (H&E, 100×) and (b) infiltration of large lymphoid cells (H&E, 400×), (c) positive CD45-LCA (100×), (d) positive cytokeratin in normal hepatocytes (100×), (e) positive Ki67 (400×) and (f) positive CD20 (400×).

Mentions: Two ultrasonography-guided needle liver biopsies were found negative and the third one showed diffuse infiltration of large sized lymphoid cells. Immunohistochemistry (Fig. 2): positive CD45-LCA, positive CD20; positive Ki67 in 80% of atypical cells; CD99 positive; vimentin positive. CD3, CD15, CD30, ACT, CK, CRO, DES, HMB45, and S100 were all negative. The diagnosis of primary large cells non-Hodgkin B-cell lymphoma was made.


Primary hepatic lymphoma: A case report.

Resende V, Oliveira TS, Gomes RT, Laboissière RS, Tavares-Junior WC, de Melo Couto OF - Int J Surg Case Rep (2013)

Histopathology of the liver biopsy shows (a) normal hepatocytes and tumor cells (H&E, 100×) and (b) infiltration of large lymphoid cells (H&E, 400×), (c) positive CD45-LCA (100×), (d) positive cytokeratin in normal hepatocytes (100×), (e) positive Ki67 (400×) and (f) positive CD20 (400×).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3860023&req=5

fig0010: Histopathology of the liver biopsy shows (a) normal hepatocytes and tumor cells (H&E, 100×) and (b) infiltration of large lymphoid cells (H&E, 400×), (c) positive CD45-LCA (100×), (d) positive cytokeratin in normal hepatocytes (100×), (e) positive Ki67 (400×) and (f) positive CD20 (400×).
Mentions: Two ultrasonography-guided needle liver biopsies were found negative and the third one showed diffuse infiltration of large sized lymphoid cells. Immunohistochemistry (Fig. 2): positive CD45-LCA, positive CD20; positive Ki67 in 80% of atypical cells; CD99 positive; vimentin positive. CD3, CD15, CD30, ACT, CK, CRO, DES, HMB45, and S100 were all negative. The diagnosis of primary large cells non-Hodgkin B-cell lymphoma was made.

Bottom Line: It is important to recognize PHL because it responds favorably to chemotherapy and may have a better prognosis than hepatocellular carcinoma or metastatic disease of the liver.This type of lesion is highly chemosensitive and early aggressive chemotherapy may result in sustained remission.This case emphasizes the importance of effective recognition of PHL considering its good response to chemotherapy and the possibility of sustained remission if early aggressive treatment is implemented.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, School of Medicine, The Federal University of Minas Gerais, Belo Horizonte, Brazil. Electronic address: vivianresen@gmail.com.

No MeSH data available.


Related in: MedlinePlus