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Neural networks underlying affective states in a multimodal virtual environment: contributions to boredom.

Mathiak KA, Klasen M, Zvyagintsev M, Weber R, Mathiak K - Front Hum Neurosci (2013)

Bottom Line: A decrease of positive affect (PA) correlated with response amplitudes in bilateral insular clusters extending into the amygdala to prolonged inactive phases in a game play and an increase in negative affect (NA) was associated with higher responses in bilateral ventromedial prefrontal cortex (vmPFC).Further our study confirmed that PA and NA are separable constructs, reflected by distinct neural patterns.PA may be associated with afferent limbic activity whereas NA with affective control.

View Article: PubMed Central - PubMed

Affiliation: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University Aachen, Germany ; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University Aachen, Germany.

ABSTRACT
The interaction of low perceptual stimulation or goal-directed behavior with a negative subjective evaluation may lead to boredom. This contribution to boredom may shed light on its neural correlates, which are poorly characterized so far. A video game served as simulation of free interactive behavior without interruption of the game's narrative. Thirteen male German volunteers played a first-person shooter game (Tactical Ops: Assault on Terror) during functional magnetic resonance imaging (fMRI). Two independent coders performed the time-based analysis of the audio-visual game content. Boredom was operationalized as interaction of prolonged absence of goal-directed behavior with lowered affect in the Positive and Negative Affect Schedule (PANAS). A decrease of positive affect (PA) correlated with response amplitudes in bilateral insular clusters extending into the amygdala to prolonged inactive phases in a game play and an increase in negative affect (NA) was associated with higher responses in bilateral ventromedial prefrontal cortex (vmPFC). Precuneus and hippocampus responses were negatively correlated with changes in NA. We describe for the first time neural contributions to boredom, using a video game as complex virtual environment. Further our study confirmed that PA and NA are separable constructs, reflected by distinct neural patterns. PA may be associated with afferent limbic activity whereas NA with affective control.

No MeSH data available.


Related in: MedlinePlus

Statistical maps of behavioral prediction of lower individual responsiveness to lack of goal-oriented behavior (threshold for cluster size according to p < 0.05 corrected). Bilateral clusters revealed a negative association of brain reactivity to lack of goal-oriented behavior in (A) the insula and (B) the amygdala. Negative association of PA and brain activation to lack of goal-oriented behavior.
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Figure 1: Statistical maps of behavioral prediction of lower individual responsiveness to lack of goal-oriented behavior (threshold for cluster size according to p < 0.05 corrected). Bilateral clusters revealed a negative association of brain reactivity to lack of goal-oriented behavior in (A) the insula and (B) the amygdala. Negative association of PA and brain activation to lack of goal-oriented behavior.

Mentions: Statistical mapping of the linear prediction of affect change correlating on the hemodynamic responses to low goal-directed behavior were calculated. PA correlated negatively with activation in bilateral insular cluster extending into the amygdala during phases low in goal-directed behavior (Figures 1A, B). Increase in NA was associated with activation in bilateral ventromedial prefrontal cortex (vmPFC) during phases without goal-oriented behavior (Figure 2A) and with right-lateralized deactivation in precuneus and hippocampus (Figure 2B; see Table 1 for the list of clusters associated with the boredom construct). The extent of the activation clusters yielded survival after correction for multiple comparisons across the volume. Peak t-values in contrast would not survive strict thresholds. This is in agreement with previous observation that subjective ratings are associated with rather distributed network activation or that the activation centers vary across individuals (Mathiak et al., 2011).


Neural networks underlying affective states in a multimodal virtual environment: contributions to boredom.

Mathiak KA, Klasen M, Zvyagintsev M, Weber R, Mathiak K - Front Hum Neurosci (2013)

Statistical maps of behavioral prediction of lower individual responsiveness to lack of goal-oriented behavior (threshold for cluster size according to p < 0.05 corrected). Bilateral clusters revealed a negative association of brain reactivity to lack of goal-oriented behavior in (A) the insula and (B) the amygdala. Negative association of PA and brain activation to lack of goal-oriented behavior.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3842844&req=5

Figure 1: Statistical maps of behavioral prediction of lower individual responsiveness to lack of goal-oriented behavior (threshold for cluster size according to p < 0.05 corrected). Bilateral clusters revealed a negative association of brain reactivity to lack of goal-oriented behavior in (A) the insula and (B) the amygdala. Negative association of PA and brain activation to lack of goal-oriented behavior.
Mentions: Statistical mapping of the linear prediction of affect change correlating on the hemodynamic responses to low goal-directed behavior were calculated. PA correlated negatively with activation in bilateral insular cluster extending into the amygdala during phases low in goal-directed behavior (Figures 1A, B). Increase in NA was associated with activation in bilateral ventromedial prefrontal cortex (vmPFC) during phases without goal-oriented behavior (Figure 2A) and with right-lateralized deactivation in precuneus and hippocampus (Figure 2B; see Table 1 for the list of clusters associated with the boredom construct). The extent of the activation clusters yielded survival after correction for multiple comparisons across the volume. Peak t-values in contrast would not survive strict thresholds. This is in agreement with previous observation that subjective ratings are associated with rather distributed network activation or that the activation centers vary across individuals (Mathiak et al., 2011).

Bottom Line: A decrease of positive affect (PA) correlated with response amplitudes in bilateral insular clusters extending into the amygdala to prolonged inactive phases in a game play and an increase in negative affect (NA) was associated with higher responses in bilateral ventromedial prefrontal cortex (vmPFC).Further our study confirmed that PA and NA are separable constructs, reflected by distinct neural patterns.PA may be associated with afferent limbic activity whereas NA with affective control.

View Article: PubMed Central - PubMed

Affiliation: Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, RWTH Aachen University Aachen, Germany ; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University Aachen, Germany.

ABSTRACT
The interaction of low perceptual stimulation or goal-directed behavior with a negative subjective evaluation may lead to boredom. This contribution to boredom may shed light on its neural correlates, which are poorly characterized so far. A video game served as simulation of free interactive behavior without interruption of the game's narrative. Thirteen male German volunteers played a first-person shooter game (Tactical Ops: Assault on Terror) during functional magnetic resonance imaging (fMRI). Two independent coders performed the time-based analysis of the audio-visual game content. Boredom was operationalized as interaction of prolonged absence of goal-directed behavior with lowered affect in the Positive and Negative Affect Schedule (PANAS). A decrease of positive affect (PA) correlated with response amplitudes in bilateral insular clusters extending into the amygdala to prolonged inactive phases in a game play and an increase in negative affect (NA) was associated with higher responses in bilateral ventromedial prefrontal cortex (vmPFC). Precuneus and hippocampus responses were negatively correlated with changes in NA. We describe for the first time neural contributions to boredom, using a video game as complex virtual environment. Further our study confirmed that PA and NA are separable constructs, reflected by distinct neural patterns. PA may be associated with afferent limbic activity whereas NA with affective control.

No MeSH data available.


Related in: MedlinePlus