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Actinic keratosis underlying cutaneous horn at an unusual site-a case report.

Nair PA, Chaudhary AH, Mehta MJ - Ecancermedicalscience (2013)

Bottom Line: Cutaneous horns are usually found on chronic sun-damaged skin.It occurs mainly in association with underlying benign, premalignant, and malignant cutaneous diseases.The commonest malignancy is squamous cell carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Pramukhswami Medical College, Karamsad, Gujarat 388 325, India.

ABSTRACT
Cutaneous horns are usually found on chronic sun-damaged skin. A cutaneous horn is a rare tumour, often conical, circumscribed, and composed of dead keratin usually derived from base keratinocytes. It occurs mainly in association with underlying benign, premalignant, and malignant cutaneous diseases. The commonest malignancy is squamous cell carcinoma. Thus, to accurately ascertain the nature of the condition at the base of the lesion and to rule out malignancy, an excision biopsy is indicated. Here, we report a case of cutaneous horn over the palmar aspect of the left middle finger in a 45-year-old man whose histopathology showed actinic keratosis.

No MeSH data available.


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(a) Hyperkeratosis and focal parakeratosis, Hematoxylin & Eosin (H & E) stain 4x; (b) loss of polarity and disordered arrangement of keratinocyte in stratum malphigian with part of normal dermis, H & E stain 10x.
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figure2: (a) Hyperkeratosis and focal parakeratosis, Hematoxylin & Eosin (H & E) stain 4x; (b) loss of polarity and disordered arrangement of keratinocyte in stratum malphigian with part of normal dermis, H & E stain 10x.

Mentions: Histopathology showed extensive hyperkeratosis and focal parakeratosis. The epidermis was thickened and showed irregular downward proliferation in dermis (Figure 2a). A varying proportion of keratinocyte in the stratum malphigian showed a loss of polarity and disordered arrangement with part of the normal dermis showing collagen bundles horizontally placed (Figure 2b). A diagnosis of actinic keratosis was given.


Actinic keratosis underlying cutaneous horn at an unusual site-a case report.

Nair PA, Chaudhary AH, Mehta MJ - Ecancermedicalscience (2013)

(a) Hyperkeratosis and focal parakeratosis, Hematoxylin & Eosin (H & E) stain 4x; (b) loss of polarity and disordered arrangement of keratinocyte in stratum malphigian with part of normal dermis, H & E stain 10x.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3842183&req=5

figure2: (a) Hyperkeratosis and focal parakeratosis, Hematoxylin & Eosin (H & E) stain 4x; (b) loss of polarity and disordered arrangement of keratinocyte in stratum malphigian with part of normal dermis, H & E stain 10x.
Mentions: Histopathology showed extensive hyperkeratosis and focal parakeratosis. The epidermis was thickened and showed irregular downward proliferation in dermis (Figure 2a). A varying proportion of keratinocyte in the stratum malphigian showed a loss of polarity and disordered arrangement with part of the normal dermis showing collagen bundles horizontally placed (Figure 2b). A diagnosis of actinic keratosis was given.

Bottom Line: Cutaneous horns are usually found on chronic sun-damaged skin.It occurs mainly in association with underlying benign, premalignant, and malignant cutaneous diseases.The commonest malignancy is squamous cell carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Pramukhswami Medical College, Karamsad, Gujarat 388 325, India.

ABSTRACT
Cutaneous horns are usually found on chronic sun-damaged skin. A cutaneous horn is a rare tumour, often conical, circumscribed, and composed of dead keratin usually derived from base keratinocytes. It occurs mainly in association with underlying benign, premalignant, and malignant cutaneous diseases. The commonest malignancy is squamous cell carcinoma. Thus, to accurately ascertain the nature of the condition at the base of the lesion and to rule out malignancy, an excision biopsy is indicated. Here, we report a case of cutaneous horn over the palmar aspect of the left middle finger in a 45-year-old man whose histopathology showed actinic keratosis.

No MeSH data available.


Related in: MedlinePlus